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When chemotherapy is used before primary treatment (surgery) to reduce the size of a solid tumor, it is called what? - ✔✔Neoadjuvant Therapy Which of the following class of drugs is cell cycle non-specific and therefore can affect the cancer in any phase of the cell cycle? - ✔✔Alkylating Agents Mutations in genetic material from exposure to chemotherapy are termed? - ✔✔Genotoxicity The Vinca Alkaloids act in which phase where they prevent cell division? - ✔✔M Phase Which of the following is likely the best way to ensure patient adherence to oral chemotherapy? - ✔✔Schedule a phone call with the patient 3-5 days after therapy is initiated To address the dose-limiting toxicity of cyclophosphamide, what should discharge education for the patient include? - ✔✔Encourage the intake of 2-3 liters of fluid per day Which of the following is true and should always be included in your discussion with patients when they go home after completing chemotherapy?
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When chemotherapy is used before primary treatment (surgery) to reduce the size of a solid tumor, it is called what? - ✔✔Neoadjuvant Therapy Which of the following class of drugs is cell cycle non-specific and therefore can affect the cancer in any phase of the cell cycle? - ✔✔Alkylating Agents Mutations in genetic material from exposure to chemotherapy are termed? - ✔✔Genotoxicity The Vinca Alkaloids act in which phase where they prevent cell division? - ✔✔M Phase Which of the following is likely the best way to ensure patient adherence to oral chemotherapy? - ✔✔Schedule a phone call with the patient 3-5 days after therapy is initiated To address the dose-limiting toxicity of cyclophosphamide, what should discharge education for the patient include? - ✔✔Encourage the intake of 2-3 liters of fluid per day Which of the following is true and should always be included in your discussion with patients when they go home after completing chemotherapy? - ✔✔Sexual relations are often allowed as long as special precautions are taken Your patient asks if it is okay to have contact with family members during chemotherapy treatments. your best response is: - ✔✔Normal contact and hugging and kissing are safe Your patient had an extravasation, which is a vinca alkaloid class of chemotherapy. What do you teach them about caring for the site when they get home? - ✔✔Apply a warm compress for 15 minutes, 4 times a day
Which of the following actions reflect an understanding of safe-handling procedures? - ✔✔Wear two pairs of chemotherapy-tested gloves and gown when handling HD exposed bodily fluids Which of the following is TRUE about the use of chemotherapy gowns with administration of chemotherapy/biotherapy? - ✔✔Gowns should be worn while administering chemotherapy by IV, oral (if splashing is likely), topical, intracavitary, and if giving aerosolized drugs Because of the possibility of exposure through bodily fluids, what is the minimum amount of time to maintain hazardous drug precautions? - ✔✔48 hours The nurse wearing a chemotherapy gown and gloves has assisted in cleaning an incontinent patient with chemotherapy infusing. The gown does not appear soiled. What should be done with the gown? - ✔✔Dispose in a yellow chemotherapy waste container Which of the following is true about pregnant nurses who care for patients receiving chemotherapy? - ✔✔Employee has the responsibility to notify employer of pregnancy PPE is required when administering chemotherapy using which of the following routes of administration? SATA - ✔✔Select all answers. When caring for the patient who is receiving chemotherapy, you notice a puddle of urine beneath the foley bag on the floor. What should be your first action? - ✔✔Remove unnecessary people from the area Which of the following may be included in a medical surveillance program? - ✔✔Administer periodic questionnaires tracking contact with HD, use of PPE, and adverse events The NCCN guidelines recommend that with the agent you are administering that you should give the following three drug combination as antiemetic premedication:
You are discussing the advantages and disadvantages of oral chemotherapy with your patient. What is one of the advantages of oral chemotherapy that can ultimately lead to adherence issues with this type of therapy? - ✔✔MOST LIKELY: Patient has an increased sense of control over treatment DEFINITELY NOT: Dosing schedules are straightforward... OR The convenience for the patient of taking medication at home Which of the following is often overlooked or sometimes even not included in the routine two-nurse check of chemotherapy orders? - ✔✔Cumulative Dose IV access is needed for a continuous infusion of vincristine and doxorubicin. Of the choices below, which would be the best location to infuse this treatment? - ✔✔Peripherally inserted central catheter with strong blood return You know from reviewing the ONS PEP resources on skin reactions, that the only intervention that is likely to be effective is/ - ✔✔MOST LIKELY: Dose interruption or modification (on ONS website) DEFINITELY NOT: Antibiotics Your patient has just arrived and is neutropenic and has a fever of 101.5. What is the most important thing to do after you obtain the ordered cultures? - ✔✔Administer empiric, broad spectrum antibiotics According to the ONS position "Education of the Nurse Administers and Cares for the Individual Receiving Chemotherapy and Biotherapy", which of the following is necessary of the nurse who administers chemotherapy? - ✔✔They complete both a didactic component and a clinical practicum to chow competency with administration principles. Which of the following is the only time it is acceptable to take a verbal order? - ✔✔Stop or hold chemotherapy Which statement describes how chemotherapy works? - ✔✔Disrupts the cell cycle during reproduction The benefits of combination therapy include: - ✔✔Synergistic effect between drugs
According to the ONS chemotherapy and biotherapy guidelines and recommendations for practice and the ONS/ASCO chemotherapy administration safety standards, how often should education and competency evaluation regarding chemotherapy administration be performed? - ✔✔When hired and annually thereafter You are scheduling a meeting to remind the staff about the proper use of PPE to ensure decreased risk of HD exposure. who, besides the nurses, should attend? - ✔✔All of the above. Which of the following safeguards should be taken to better prevent exposure to HD? - ✔✔Flush the toilet with the lid down or place a plastic backed pad over the toilet When intrathecal chemotherapy is prepared for administration, what additional safety step beyond the usual chemotherapy safety checks, must be followed? - ✔✔Specialized labeling and handling If a nurse is pregnant or breastfeeding, the ASCO/ONS recommendation is for the employer to? - ✔✔Offer alternative duty to protect against HD exposure If you have an accidental exposure of HD on your clothes and skin, what should be your first or initial response? - ✔✔Remove the affected clothing immediately When is it necessary to wear a NIOSH-approved respirator? - ✔✔When cleaning up a hazardous drug spill