Active methylene compound , Summaries of Organic Chemistry

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ORGANIC CHEMISTRY. UNIT 1: ACTIVE METHYLENE COMPOUND : = Acidity of a - hydrogen atom ( formation of eolate): «CH band in non polar because of very small difference in electronegativity of ¢ and h ator. However when C-H bond Is attach with carbonyl group then C-H bond become polar. As @ resulta removes proton when undergoes reaction with base and farm anion (the anion farmed is resonance stabilized } Given as: ‘The resonance stabilized anal when reacts wrth proton donate then there are two passibilites.ff if proton is added to carbon then anginal ‘compound is found called keto form and if proton added to oxygen atom than compound form Is called enol shown as: The resonance stabilized anion is alsa called enolate anian because it gives rise to endl =KETO ENOL ISOMERISM IN ETHYL ACETO ACETATE: Ethyl acetoacetate show keto enol isomerism. This isomerism involves 1, 3- migration of h atom from one polyvalent atom to another polyvalent atam in result in formation of isomeric form (same molecule formula) these forme are called tautomers which exist in equilibrium and this isomeriam is called tautomerism shown as: sEVIDENCES FOR PRESENCE OF KETO GROUP AND ENOL GROUP IN ETHYL ACETO ACETATE: 1. Presence of keto group: Follos ridences of presence of keto group given as: ing reactions give