Amorphous Solutions and Dispersions
About 40% of newly developed medicinal chemical entities have poor water
solubility, and 90% of drugs under development can be classified as poorly
soluble drugs. In response to this problem, synthetic chemists have made salts
with weak bases or weak acids and poorly soluble drugs, but in fact only 20%
~ 30% of new chemical entities are easy to form salts, and the remaining 70%
~ 80% of new chemical entities. A solid dispersion (SD) refers to a dispersion
system in which the drug particle size is within the range of 0.001 to 0.1 μm in
a certain state and uniformly dispersed in a solid carrier. As an intermediate of
pharmaceutical preparations, solid dispersions can increase the dissolution of
poorly soluble drugs, improve bioavailability, delay drug release, increase drug
stability, and solidify liquid drugs.
Fig.1 Schematic diagram of solid dispersion formation
Our Services
As a supplier of pharmaceutical preparations, CD Formulation has pharmacy
and other professional researchers and experimenters, and has extensive
experience in drug development. Our company can customize the carrier
