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APMLE LATEST UPDATE 2025 PATHOLOGY EXAM WITH ACTUAL QUESTIONS AND VERIFIED ANSWERS (RATED, Exams of Pathology

Kansas City University of Medicine & Biosciences (KCU)Pathology

1. What blood group is the universal donor - ✔✔O- 2. What causes Parkinsonianism - ✔✔Lack of dopamine 3. MG is a result of - ✔✔Ab's against AcH receptors at NMJ 4. CREST syndrome is associated with - ✔✔Calcinosis, Raynauds phenomenon, esophageal dysmotility, sclerodactyly, telangiectasia, and diffuse scleroderma 5. What can give you pulmonary embolus - ✔✔DVT 6. What is the most common chromosomal disorder - ✔✔Down Syndrome (trisomy 21) Note: it is also related to ALL 7. Mesothelioma and bronchogenic CA are associated with - ✔✔Asbestos

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APMLE LATEST UPDATE 2025 PATHOLOGY
EXAM WITH ACTUAL QUESTIONS AND
VERIFIED ANSWERS (RATED A+) 100% PASS
1. What blood group is the universal donor - ✔✔O-
2. What causes Parkinsonianism - ✔✔Lack of dopamine
3. MG is a result of - ✔✔Ab's against AcH receptors at NMJ
4. CREST syndrome is associated with - ✔✔Calcinosis, Raynauds phenomenon, esophageal dysmotility,
sclerodactyly, telangiectasia, and diffuse scleroderma
5. What can give you pulmonary embolus - ✔✔DVT
6. What is the most common chromosomal disorder - ✔✔Down Syndrome (trisomy 21) Note: it is also
related to ALL
7. Mesothelioma and bronchogenic CA are associated with - ✔✔Asbestos
8. Hyperglycemia can be caused by all except - ✔✔Insulin
9. Emergency problem with insulin - ✔✔Hypoglycemia
10. Emphysema - ✔✔Alpha-1 antitrypsin deficiency
11. When vitamin B12 is not absorbed it causes - ✔✔Pernicious anemia
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Partial preview of the text

Download APMLE LATEST UPDATE 2025 PATHOLOGY EXAM WITH ACTUAL QUESTIONS AND VERIFIED ANSWERS (RATED and more Exams Pathology in PDF only on Docsity!

APMLE LATEST UPDATE 2025 PATHOLOGY

EXAM WITH ACTUAL QUESTIONS AND

VERIFIED ANSWERS (RATED A+) 100 % PASS

  1. What blood group is the universal donor - ✔✔O-
  2. What causes Parkinsonianism - ✔✔Lack of dopamine
  3. MG is a result of - ✔✔Ab's against AcH receptors at NMJ
  4. CREST syndrome is associated with - ✔✔Calcinosis, Raynauds phenomenon, esophageal dysmotility, sclerodactyly, telangiectasia, and diffuse scleroderma
  5. What can give you pulmonary embolus - ✔✔DVT
  6. What is the most common chromosomal disorder - ✔✔Down Syndrome (trisomy 21) Note: it is also related to ALL
  7. Mesothelioma and bronchogenic CA are associated with - ✔✔Asbestos
  8. Hyperglycemia can be caused by all except - ✔✔Insulin
  9. Emergency problem with insulin - ✔✔Hypoglycemia
  10. Emphysema - ✔✔Alpha- 1 antitrypsin deficiency
  11. When vitamin B12 is not absorbed it causes - ✔✔Pernicious anemia
  1. What fluoresces coral red under the Wood's lamp - ✔✔Erythrasma (caused by Corynebacterium)
  2. Disease characterized by reversible bronchospasm - ✔✔Asthma
  3. What is going on with a patient w/ neuropathy and elevated liver enzymes (AST:ALT inc ratio)? - ✔✔Alcoholism
  4. First Tx for NIDDM - ✔✔Weight loss
  5. Draining granular foot lesion - ✔✔Mycetoma
  6. Down syndrome has an association with - ✔✔Leukemia
  7. Disease characterized by aneurysms - ✔✔Marfans
  8. Which is not a risk for atherosclerosis - ✔✔Alcoholism
  9. What is the cause of Libman sacks endocarditis - ✔✔SLE
  10. What disease replaces muscle tissue with fibrous material and fat in a child - ✔✔Duchenne's muscular dystrophy
  11. Circular rings of cartilage in vessels, non-occlusive - ✔✔Munckeberg's medial sclerosis (tunica media)
  12. Patient with an irregular heart beat has a stroke, what is the cause - ✔✔Cause is embolic stroke
  13. Young male with thrombosis (smoker) - ✔✔Buerger's
  14. Irregular cells - ✔✔Dysplasia
  1. Goodpasture syndrome - ✔✔Attacks lungs and kidneys, pulmonary hemorrhages, renal lesions, hemoptysis, hematuria, anemia, proliferative glomerulonephritis, anti glomerular basement membrane, antibodies produce linear staining on immunofluorescence, type II hypersensitivity RXN, most common in med 20 - 40, glomerulus & pulmonary
  2. Hyperthyroidism - ✔✔Heat intolerance, hyperactivity, weight loss, chest pain/palpitations, arrhythmias, diarrhea, increase reflexes, warm, dry skin, fine hair, (Decrease TSH) if primary and increase total T4 and free T4, increase T3 uptake
  3. Hypothyroidism - ✔✔Cold intolerance, hypoactivity, weight gain, fatigue, lethargy, decrease appetite, constipation, decrease reflexes, myxedema (facial/periorbital), dry cool skin, coarse brittle hair. Increase TSH, decrease total T4, decrease free T3, and decrease T3 uptake
  4. Gout - ✔✔Involves purines
  5. What dz has antibodies to dsDNA - ✔✔SLE
  6. What dz causes pleural mesothelioma - ✔✔Asbestosis
  7. What dz presents with Reed Sternberg cells, fever, painless lymphadenopathy - ✔✔Hodgkin's dz
  8. Most common cause of esophageal inflammation - ✔✔Gastric reflux
  9. Where is a peptic ulcer located most often - ✔✔Proximal duodenum
  10. What is the most serious type of glomerulonephritis in SLE - ✔✔Diffuse
  11. What causes bilateral ankle edema - ✔✔CHF
  1. Pt presents with eye, skin rash, periorbital edema, and muscle weakness in the shoulder and pelvic girdle - ✔✔Dermatomyositis
  2. Normocytic, normochromic anemia does not include: but it includes intravascular & extravascular hemolysis - ✔✔Iron deficiency
  3. Autosomal recessive defect affecting electrolytes - ✔✔Cystic fibrosis
  4. Pt with papule, plaques, and white scales - ✔✔Psoriasis
  5. Mother donates a kidney to her child, what type of graft is this - ✔✔Allograft
  6. Myasthenia Gravis is what type of hypersensitivity - ✔✔II
  7. TB is what type of hypersensitivity - ✔✔IV
  8. SLE and Sjorgens are what type of hypersensitivity - ✔✔III
  9. Paget's Disease of bone - ✔✔Condition caused by disordered bone remodeling, where excessive bone reabsorption initially results in lytic lesions, to be followed by disorganized and excessive bone formation (aka osteitis deformans), has an unknown etiology. Presence of microfilamentous inclusions in paracrystalline array suggests presence of a virus, increase in alkaline phosphatase levels that correlate with osteoblastic activity. Histologically its feature is of abnormal arrangement of lamellar bone, with islands of irregular bone formation-jigsaw puzzle/mosaic patter in bone. Triphasic uncoupling of osteoblastic and osteoclastic activities
  1. Hot - osteoclastic resorptive stage - tumor like
  2. Mixed stage of osteoclastic + osteoblastic activity - larger than normal bone
  3. Cold-burnt out stage - little cellular activity thickened disordered bones
  1. Lesch Nyhan syndrome is associated with - ✔✔Purine salvage problem owing to absence of HGPRTase which converts hypoxanthine to memophosphate (IMP) and guanine to guanosine memophosphate. An X linked recessive - increase uric acid production
  1. A highly malignant rare tumor of striated muscle - ✔✔Rhabdomyosarcoma
  2. Congenital/acquired outpouching of the wall of the colon - ✔✔Diverticulosis
  3. Bells palsy affects which CN - ✔✔VII
  4. What are the components of virchows triad - ✔✔Blood flow stasis, hypercoagulability, endothelial injury
  5. What dz is characterized by dry mouth, dry eyes, and RA - ✔✔Sjogrens syndrome
  6. What term is used to describe congential hypothyroidism with retardation - ✔✔Cretinism
  7. The dx of pseudogout is established by demonstration of what in the joint fluid - ✔✔Ca++pyrophosphate
  8. Macrocytic anemia results in deficiency of - ✔✔Folate and B
  9. Actinic keratosis can or cannot become malignant - ✔✔It can
  10. What causes fever 24 hours after surgery - ✔✔Atelectasis
  11. Malignant melanoma in situ - ✔✔Lentigo maligna
  12. Can superficial varicose veins lead to emboli - ✔✔No
  13. Reyes syndrome - ✔✔Occurs with AS in kids
  1. Gaucher's dz - ✔✔Spingolipidoses, deficiency of b-glucocerebrosidase leading to glucocerebroside accumulation in brain, liver, spleen, and bone marrow. Gauchers cells with "crinkled paper" enlarged cytoplasm
  2. Niemann pick dz - ✔✔Deficiency of sphingomyelinase causes build up of spingomyelin and cholesterol in reticuloendothelial and parenchymal cells. "cherry red macula" "No man picks his nose with his sphinger.
  3. ANA titer seen in - ✔✔SLE
  4. Protein s - ✔✔Anticoagulant and w/out it you are going to get clots, young girl with multiple miscarriages and DVTs
  5. Polycythemia vera - ✔✔Increases erythrocytes-increases blood viscosity