Download Bioinorganic , porphyrin ring and more Lecture notes Chemistry in PDF only on Docsity!
~_ar 3) 3 } ©O7di na j } pla A) £ : {Ul Jagat f Hapy IX " ji 5" if , 7 \ ¥~ / os . » \\ L ns \ > \ NRK gee \ Ne x | t=" & hhara en sha leOku ey od lena Pp. prvi f ) | planar or nearly planar ming System Ave Jery . Jeomeln c Stres¢ | All -bond length (1\@4-lurpm) ¢ ana guy eee) 107 “126° Of iwoet at fersional angle (207) Axe normal fo al = =) ) } gp hygndised © + @ Cerby 1) Cua | () “Jelradentate Chelate ligands oftle, depmtpnahon - Single Or double negative Charge ¢- Can bind coordinately tablle metal tons > Cuet Ab Lt be hazard ( Ailfotiaton ) only th Al) ynetal coord meted / y ttnalil i bond’ are broken Jimultaneow| “I (ak fe heal cheahn 9 [70D fet acquisition, 4 aterual —pon crurat pechires Oh the tor vith ty A rut a] YUCICN ~— Fro Shorag ¢ Limast all lying Orcar PToter P : 19 Om1Sey ‘including ¥ Found un animal 14 Py i DaChe.+ + Serves the yitot £ O . Plar i - ; i ologqicai Lomng IF 2 a y Iron in a Soe ate ee 3 role of ! y nor L. Tow © ra = yeleasing it When needed tor d ho eMuiar Gro OCes Jay Wiee PNA Synth \ = 1 ‘d sHhests Pres pir ation < pekabo is 201 1.5m Crruckure 1 x Te Ferrin Is Cormpoted o te of 2% Poly pephide unity #hok Assemble fo | jor Za Hollow, nearly oe eal Shett subunit Two = thaw Cueavy. —— SRE ned * m Cueavy)— Contant a feyroxidate centre aS caidation Of 5 toe “resp Gach , tubunit if made, up Ok paut k four Sleepolie elie = ~ Gund ean * helix al cterm in| "EL aonelix “bundle wlth a Shoot mt pb ae —[ thak ab ads Ww “Cligomesszerian | helical ese frabiliees ae Cece ss ~Grannell or _yron ~ provement “Ane. gueral) pron ¢ ee thin She y- chain ane ne Conversion OF en by sO |= Ferrexidate mel = Z ~jocaled Ol | aon Ticien cepa aeee ett (ferrous) \ons a “pee (Fernie)! oy Weer So Saat OxnGen Conn? [oo ies Af + Op + 6Y42e —7 4 feo dehined Ghemicay mimic -+he (huchire oh achive BNSC Seah r biolegicof spetualtp metallopro}e ny 4 enzymes feohal feall in biginergantc Chemis hry rsanding +he hbehaulauz oh Corn plew fultem Under Simpler -2£ mare Contoiled 6% Condihons G). Structural modealf — prodeti gre designed +0 peplicate | } geomehy and bending Patten ~b th the pictegicay | metal cenker — Focus SCR on Shape 3 bond lengyy , bond angles Coowdina Hon -nuronment ares 4] Clusters amd the Iron In ferrvecdon'5 wow Funckona) Models = Fhee are designed to rnimic the peach vity or CARLY C Bena Gia ok H+ the e meral Cenkt r even Is the (hudckure tJ mob enaOy | the Jann _ Focus js on 7x9 Ay pes Whee | oxidation ) pred, Ets = Somes | Syorhorc models +hak mimic he. and. pelea te bebauiour eh Hb _ Biomimebhe model — “thete a _ epi fie (kal, ipcltucee saencly EST, Gorey “resemble Ea biologicay System tn Phadux _Yeathvity 7 Sometimes < even 10 > 4ulahion | mecha ott, ee = Sy ntheic hydrogenar: fe “yredaly _preton redo © Simila as -Qracdient 7 Qated Char Liq are ach brans pot ae aGhVvs aie Sail and voltage gaaled Channet F jlorang \ RICE Ae Pump = efeps invewwed 'n ATP Dependent Nat-K+ pump onic gradient i arn energy dapendenr procels uohere the energy Ublized 1 Supplied by the pydrolys't OD Ate tu _ sop ¢ inorganic phosphate = mechani se yenponsib|< jor genessnien Opes J -_ b tne ene me aot ea ATPase ae gradient noted bles i cal- ye process _—— - ENeyme_ ar =a ——s+ Ana Mye in mee. he CP rof — char ¢ 2c Step - OL Th involves E oh se @ met franspor out for every trons) post re , the membrane ~ SNA fons ae * pur pec . : Eauaiet bp len _ = « Hghhly © “a. The “yd vols ne Ate s é 7 oenceel \or the faite co Wn an spe process Sell oe encoun — ous _puncion of the bss gia vyeswt tn unproducnve _ ry dsolys's oh an ane ———<<—— IS Poe {€ este Fi D. i NRAY Or ropid ¢ uch AS atnerahoap, ak fates i] 9a, tran/rs) AChoOn Petenhay +4 on |I9 Nerue cam eCsiSk ing Uawsehy stove ; dame —Or€ opens + cabahje Otheas thal are Closeal| oF tnachualcd 4. no an $ Post ' = te ACeryiGholine xeceptor- jarge 4 Complen cmoieaile Large oligomeric glycoprotein = \t Contains totol of fue powypephde -chainys oh jour | Cibleren- types wlth an overal) Storchiommelry Of %o BIC h here wank a aE: al Q- | —~ Tobol molmapt Boakilodathn. = tach glycopsoteanr binds up to hwo molec er oh the D Nearapraosmilter - aeahy) choline one Of CAth ah the itn robes ycnoline penton ites — Piao J — Ave Gucbitn ibs j are arranged - ina a pentagonal | Gtr OY "5.0 wn of a aelahyery oPeEn cnr cor SA lenge dlornan extends to the entractular ide Oh) the membrane, Whereas smaller one “Us preent ¢ on inkra celular tide | : = f ase UIUAN undes kinel¢ Sno] OWING ty Wear (Charadevo, c-c ¢m-—c bonds Although 4psmlaneaus fel] adlemb\y ha, produce g Jax { i. P moder, for ie Gruthure) 4 peck 6 pl jf TO Peaira 6 i Che nod ; | MEFUloprowin Cores, cluplicahing + = eal, . : Ocula't ><4uires more Complem Ligand = Uth ae —_™ L— Development of Compartmentalized Vigor all a hes! . 61 MA Cropolycy Clie molecies has “pba a | | variery ee Sretesies for Palmore ee | Cove Ehernishy ke Sythe Re mode ae ee Y pPrptuns | YFe-U( . Cube - [COmplexer vo} thi 3 Nd - Wer ail P< par boow >
Qre?t RSCR a) [reese J, hf = tani 4 3:29. o}, Ca (, cbt p ph) 19 methano| yielded [Rasy (GeHiaph), 7 __ Custer, INF XN Home Oh4 thiol tf COMfumMed| ; [re Iron formally po ta La Jered | <4 Ut eal ee = : OY Nee fe i =i ist ee Jc ate sl) Wed — a e tur (oud 4 € a +0.) > ee / fof lth Teas i € Subshf 2 or 5 bind one felt ion along 39 a4 G& Sunergishe anion Og XA ta] J J oh OF AINALE ef vol, © HYyYesine rey aie, ale Pherola je oO Bom) Aspazk¢ aud jesidue i CCarboouys g Troup) hiskeline -regialus¢ nifrager ) ’ One OXY 9 ee pon Co, Ls Cont wee ae a eaten: melecute x anothe ne ics Toxyge, adap Avec “eted = S2ound tran Hae tobe 6 J fake aun open Gime Trancfersin 1 Is ice binds ie fo mer nbreine | _Supace _2