BIOMOLECULES AND CELL
Amino acid. —> proteins
Nucleotides —> DNA
Monosaccharides —> Polysaccharides
Nucleosome —> chromatin —> DNA
Schleiden and
Schwann
gave the idea of
cell.
Accumulation of
LIPOFUSCIN, a
pigment rich in lipid,
and protein has been
implicated in ageing
process.
Zellweger: rare
disease, absence of
functional
peroxisomes.
Nucleolus is rich in r-RNA which enter cytosol
through nuclear pore.
Hutchinson-Gilford progeria syndrome (HGPS)
rare condition of aging beginning at birth due to
distortion of nuclear envelope due to
accumulation of abnormal protein namely
lamin-A.
Mitochondria
The components of electron transport chain
and oxidative phosphorylation are present in
inner mitochondrial membrane.
Mitochondrial matrix enzyme also participate
in synthesis of heme and urea
It is hypothesised that mitochondria have evolved from aerobic
bacteria and it is believed that during evolution the aerobic
bacteria developed a symbiotic relationship with a primordial
anaerobic eukaryotic cells that ultimately led to arrival of aerobic
eukaryotes.
