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An overview of the cell cycle, including the stages of mitosis and cytokinesis, as well as an introduction to meiosis and its role in generating genetic variation. The document also includes references to external resources and videos for further study.
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All diagrams, tables, and external information is property of Pearson Campbell Biology 11th^ edition, unless BIO 1305 – Modern Concepts in Bioscience I – Campbell Textbook Week 9 – Chapters 12 & 13 Hi guys! I can’t believe we are halfway through the semester! I hope you are enjoying your biology class. Today we are going to talk about chapter 12, which covers the cell cycle, and we are going to start talking about the genetics aspect of biology in chapter 13. Don’t forget that Gabriel and I hold weekly group tutoring sessions on Thursdays from 5-6 pm. Sign up to join us here: https://baylor.edu/tutoring. We would love to see you there! Keywords for this week: Cell Cycle, Binary Fission, Mitosis, Meiosis As usual, I’ve linked videos to aid you as you read through the resource. After you read each section, watch the videos as review! Chapter 12: The Cell Cycle Cell division is vitally important and is the reason you are who you are! Before we talk about cell division, let’s talk about some cellular features that will play a role in the cell’s life cycle. Each one of your cells contains a copy of your genome , which is all of your genetic information. Your genome is packaged into chromosomes which have to be copied before your cells can divide. Our somatic cells (body cells) specifically have 46 chromosomes, while our gametes (reproductive cells ) have 23 chromosomes. After chromosomes are copied before division, each chromosome will have two sister chromatids that are attached to each other. The picture on the right shows that the sister chromatids of a single chromosome are attached at their centromeres. Video: Cellular Organization and Bacterial Cell Division Now we can start laying the foundation of cell division. There are two main phases in a cell’s division: Mitosis: division on genetic material Cytokinesis : division of cytoplasm Stages of the Cell Cycle Mitosis is part of the cell cycle, but it is actually the shortest part of the entire life cycle of a cell. When a cell is not dividing, it is in interphase , a period of growth and development. Interphase consists of several distinct phases: G1 – growth S – “synthesis” G2 – more growth
All diagrams, tables, and external information is property of Pearson Campbell Biology 11th^ edition, unless As you can see, mitosis makes up only a small part of a cell’s life. However, it is extremely important and consists of many stages. Your book has a very detailed picture of these steps, but for now I just listed the main points for each stage: Prophase —DNA condenses, mitotic spindle begins to form Prometaphase —nuclear envelope breaks down, kinetochore forms Metaphase —chromosomes line up at the center Anaphase —sister chromatids pull apart Telophase —nuclei reform, chromosomes relax Cytokinesis —cytoplasm divides and two daughter cells are formed Video: Phases of Mitosis Looking closer at cytokinesis … When a cell enters cytokinesis, a cleavage furrow forms and essentially “pinches” the cell into two. Specifically in plants, a cell plate forms and grows until it fuses with the cell membrane. Binary Fission Everything we just listed is specific to eukaryotic cells. Division in prokaryotic cells is different and is called binary fission. Here, the prokaryotic cell grows to twice its size before it splits in half. Image taken from: https://study.com/academy/lesson/binary-fission-definition-steps-examples.html
All diagrams, tables, and external information is property of Pearson Campbell Biology 11th^ edition, unless
This helpful image shows the main differences between mitosis and meiosis: Three things occur in meiosis I that make it unique from mitosis: Synapsis and crossing over Homologous pairs align at metaphase plate Homologs separate Video: Mitosis vs Meiosis One last key thing to note about meiosis is the way that it generates genetic variation. There is a concept that is extremely important to understand if you plan to take a genetics class later on: Independent assortment of chromosomes – during meiosis I, homologous chromosomes line up at the metaphase plate. Homologs arrange themselves randomly! In the image above, notice in metaphase I that the red and blue pairs of chromosomes do not all link up on the same side. This generates variation in the chromosome composition of the daughter cells at the end of the process. Video: Origins of Genetic Variation among Offspring