Cardiovascular System Development
Cardiovascular disease is one of the most serious diseases that endanger human life
and health in China and the whole world. Its prevalence and mortality rank first
among all kinds of diseases. Cardiovascular diseases include hypertension,
atherosclerosis, stroke and myocardial infarction. These cardiovascular diseases have
a common pathogenesis and basic pathological processes, including cardiovascular
cell migration, hypertrophy, proliferation, and apoptosis. It has a change in cell
phenotype, morphological structure and function, that is, cardiovascular system
development occurs.
Cardiovascular system development refers to the changes in morphological structure
and function of blood vessels in response to changes in the internal and external
environment during growth, development, aging, and disease. The cardiovascular
system development of cardiovascular disease is essentially response of the body to
the homeostasis imbalance of the cardiovascular system caused by different
pathogenic factors. The material basis for maintaining the homeostasis of the
cardiovascular system is a cardiovascular active substance that functions as a
regulator. Cardiovascular active substances include proteins, peptides, enzymes,
growth factors, cytokines, adhesion molecules, and information transfer molecules
that regulate cardiovascular growth, development, morphological structure, and
functional activities. The study of cardiovascular active substances is also one of the
most active and important frontiers in life science research.
