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CCTC CERTIFICATION REVIEW LATEST (2024\2025) WITH VERIFIED QUESTIONS AND ANSWERS RATED A+
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CCTC CERTIFICATION REVIEW LATEST (2024\2025) WITH VERIFIED QUESTIONS AND ANSWERS RATED A+
Absolute Contraindications for liver transplant Severe cardiopulmonary disease, uncontrolled HIV, poorly controlled Psych illness, noncompliance, anatomical abnormalities precluding adequate surgical reconstruction Reason for not accepted for liver TX Hepatocellular Carcinoma (HCC) outside Milan Criteria What is NAFLD? Nonalcoholic Fatty Liver Disease− caused by obesity, hyperglycemia, elevated serum lipids, and high BP What is NASH? Non−alcoholic steatohepatitis. Can lead to cirrhosis 3rd common indication for liver TX. What is the MELD score? MELD(Model for End Stage Liver Disease) is a predictive model of death within a 3 month period. Ranks your degree of sickness, shows how much you need a liver transplant. The higher the number, the more urgent case is. Score ranges from 6−40. *Score for HCC capped at 34. Calculated using: −INR −Bilirubin −Creatinine −Sodium MELD > 14 needed for liver transplant What can green drainage post liver TX indicate? Bile leakage What can a rise in ALP post liver tx indicate? Can be a sign of biliary complications or cholestasis Lab changes are indicate of graft dysfunction. Which values will be elevated for liver tx? Elevated AST and ALT
Immediate return to OR for revascularization of organ Symptoms of bleeding post liver transplant include: Increased swelling in abdomen Pallor Clinical manifestations of hypovolemia Some BP meds may increase cyclosporine or tacrolimus levels, name 2 Diltiazem(Cardizem) Verapamil(Calan) What are causes of cholestasis post liver transplant Rejection Sepsis Drug toxicity Preservation injury Clinical manifestations of cholestasis Cloy or white stools Dark urine Itching Pain in upper right quadrant Jaundice Inability to digest certain foods N&V Locations of bile leaks post liver transplant Anastomosis site T tube exit site Along the t tube tract at time of removal Within the liver as result of bile duct destruction(bile leak) From the cut surface in split liver, living donor transplant, or after biopsy CMV clinical manifestations High fever, rigors, body aches, night sweats CMV prophylaxis Valganciclovir ( valcyte) for 3 months S&S of rejection post liver TX Fever, ictera(yellowing of sclera), jaundice, RUQ pain, fatigue, malaise, pruritis *confirmed by biopsy Lab changes with rejection s/p liver TX
Elevated AST, ALT, bilirubin What color should t tube drainage be post liver Tx? Golden brown Types of rejection in transplant Hyperacute acute(cellular and antibody mediated) chronic Signs of acute rejection s/p liver Tx Fever, listlessness, liver pain, loss of appetite, irritability, fatigue, abdominal distention, jaundice, abnormal transaminases What to monitor post liver bx VS, signs of bleeding(tachycardia, hypotension) If has T tube monitor for blood in bile Hgb hct typically check 4 hrs after bx Bed rest 4−6 hrs after bx When should pt notify staff post bx? Severe abdominal pain Dizziness/lightheadedness SOB Bleeding from bx site Calcineurin inhibitors Tacrolimus(prograf) Cyclosporine(neoral or gengraf) Antiproliferative agents Azathioprine (imuran) Mycophenolate mofetil(cellcept) Mycophenolic Acid(myfortic) Corticosteroids Methylprednisolone (solu−medrol), or IV or Oral prednisone Which medication causes increased cholesterol levels? Sirolimis(rapamycin/rapamune) Why are induction agents given pre− or intraoperatively in transplant?