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RARITAN VALLEY COMMUNITY COLLEGE
ACADEMIC COURSE OUTLINE
BIOL 245 CELLULAR AND MOLECULAR BIOLOGY
I. Basic Course Information A. Cellular and Molecular Biology, BIOL-
B. Modified Course
C. Date of Proposal: Semester: Spring Year: 2009
D. Sponsoring Department: Science & Engineering
E. Semester Credit Hours: 4
F. Weekly Contact Hours: Lecture: 3 Laboratory: 3
G. Prerequisites: General Biology I (BIOL-101), General Chemistry I (CHEM-103)
H. Laboratory Fees: Yes
I. Dr. Margaret Czerw, mczerw@raritanval.edu
II. Catalog Description
Prerequisite: General Biology I (BIOL-101) and General Chemistry I (CHEM-103)
This course serves as a second year course in the Biotechnology Program. This lecture and laboratory course provides an overview of the structure and function of prokaryotic and eukaryotic cells. Topics include DNA replication, transcription, translation, mutation, gene regulation, membrane function, cellular communication and secretion. Laboratory stresses molecular and recombinant DNA techniques, protein purification and characterization and cell culture techniques.
III. Statement of Course Need
This course serves as the second year Biology course in the Biotechnology Associates Program. This course will also serve as a second year course in the Biology Option of the Math and Science A.S. Degree Program. This course may also be an elective to other science majors in Biology, Chemistry and Environmental Sciences by those students meeting the prerequisites.
IV. Place of Course in College Curriculum
A. Free elective
B. This course does not satisfy a general education requirement.
C. This course meets a requirement for the Biotechnology AS Program.
D. Course transferability; for New Jersey schools go to the NJ Transfer website,
www.njtransfer.org. For all other colleges and universities go their individual websites.
V. Outline of Course Content
A. Introduction to Cells
B. Biochemistry
- Chemical bonding
- Macromolecules
- Energy C. Protein Structure and Function
- Protein Structure
- Protein folding
- Enzymes
- Purifying, detecting and characterizing proteins
D. Molecular Genetic mechanisms
- Structure of nucleic acids
- Transcription, translation and protein synthesis
- Control of gene expression
- DNA replication
- Molecular structure of genes and chromosomes
E. Biomembranes and Cell Architecture
- Components and function
- Membrane transport
- Organelles
- The cytoskeleton
- Microscopy
F. Molecular Genetic Techniques and Genomics
- DNA cloning
- Analysis of gene structure and expression
- Identifying and locating human disease genes
G. Cell cycle and cell growth control
- Cell signaling
- Checkpoints
- Cell cycle control
- Cancer
VI. Educational Goals and Learning Outcomes
A. Educational Goals Students will:
- Develop an ability to apply principles and generalizations already learned about science and technology to new problems and situations (GE-RVCC 1; NJ GE 3)
- Karp, G. (2002) Cell and Molecular Biology: Concepts and Experiments, 3 rd^ Ed. John Wiley and Sons, Inc. B. Supplementary Textbook
- Karp, G. (2002) Cell and Molecular Biology: Concepts and Experiments, Problems Book and Study Guide, 3 rd^ Ed. John Wiley and Sons, Inc. C. Current scientific articles D. Web resources E. Computer-based resources
(Please Note: The course outline is intended only as a guide to course content and resources.
Do not purchase textbooks based on this outline. The RVCC Bookstore is the sole resource
for the most up-to-date information about textbooks.)
XI. Resources The library has the resources necessary for students to complete assignments necessary for this course.
XII. Honors Options This is not an honors course.
