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classification_of_antimicrobial_agents, Summaries of Nursing

classification_of_antimicrobial_agents

Typology: Summaries

2017/2018

Available from 08/18/2023

rohith-inapanuri
rohith-inapanuri 🇮🇳

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Classification of Antimicrobial Agents
Antimicrobials
can
be
classified
a/c
to
several
ways
:
TA
]
Mechanism
of
Action
:
ii.
Drug
inhibiting
cell
wall
synthesis
:
iii.
Drugs
inhibit
Protein
synthesis
:
ciiis
Drugs
causing
leakage
from
cell
Membrane
:
car
Polypeptide
Antibiotics
:
Polymixin
B.
Cole
's
tin
.
and
tyrothricin
pf3
pf4
pf5

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Classification of Antimicrobial Agents

  • Antimicrobials (^) can be

classified

a/c to^ several^

ways : TA ] Mechanism^ of Action^ : ii. Drug inhibiting^ cell wall^ synthesis : iii. (^) Drugs inhibit^ Protein^ synthesis : ciiis Drugs (^) causing leakage^ from^ cell Membrane^ : car Polypeptide Antibiotics (^) : Polymixin B.^

Cole 's tin^.

and tyrothricin

(b)

Polyene

antibiotics : Amphotericin B^ ,

nystatin

.

hamycin. natamycin

(C) Azoles^ :^ ketoconazole ,

fluconazole ,

itraconazole. in

Drugs affecting

Nucleic (^) Acid (a) DNA^

gyrase

inhibitors :

Fluoroquinolones ,

Ciprofloxacin.

Novobiocin (b) (^) RNA

polymerase

inhibitors (^) :

Rifampicin

a

Drugs destroying

DNA : (^) Metronidazole , Nitro

furan

  • to in. cdi Nucleotide (^) / Nucleoside^

analogues

:

Acyclovir.

zidovudine (^) , Ido (^) ✗ uridine in

Drugs affecting Intermediary

Metabolism (^) :

(a) Inhibiting

Folic (^) acid

Synthesis

:

Sulfonamides ,

Dapsone ,

Para amino

salicylic

acid (b) DHF^ Rare Inhibitors^ :

Trimethoprim ,

Pyrimethamine

Pnoguanil

Methotrexate

[

B. ] Based on

Type of Action^

:

( is^ Bacteriostatic^ ( stop the

growth of

bacteria (^) ) in (^) Bactericidal (^) ( kills bacteria )

(c)

Based on

spectrum of Activity

:

( is^ Narrow^ Spectrum -^ Penicillin^ G

, streptomycin^ ,

Erythromycin

in Broad

spectrum

Tetracyclines , chloramphenicol.

1- D) Based^ on^ Type (^) of Organism : ii. Antibacterial -^ Penicillins^ , Erythromycin , etc ciii Antifungal

Griseofulvin ,

Ketoconazole etc Iii ,^ Antiviral^ - Acyclovir (^) ,^ Amantadine^ ,^ Zidovudine^ etc ( in^ Anti^ protozoal

  • Chloroquine , Metronidazole , Diloxanide etc

cvi Anthelmintic^ - Me bend azole

, Pyrantd.

Diethyl carbarn azine etc^. 1- E^ ] Based (^) on Therapeutic Index (^) (TI^ ) TI →^ Quantitative Measurement^ of Relative^ safety of (^) drug.