Download Clinical pharmacy - Test 1 and more Exams Pharmacy in PDF only on Docsity!
Test 1
Questions
Questions 1–
Directions: Each group of questions below consists of five lettered
headings followed by a list of numbered questions. For each
numbered question select the one heading that is most closely
related to it. Each heading may be used once, more than once,
or not at all.
Questions 1–3 concern the following:
A o MCHC
B o lymphocytes
C o HbA1c
D o INR
E o thrombocytes
Select, from AA to EE, which one of the above:
Q1 may be decreased in iron deficiency anaemia
Q2 may have an increased value in viral infections
Q3 may have a decreased value in idiopathic thrombocytopenia purpura
Questions 4–6 concern the following:
A o tachypnoea
B o hypoxia
C o afterload
D o myopathy
E o dysphasia
Select, from AA to EE, which one of the above is manifested by:
Q4 muscle weakness and muscle wasting
Q5 rapid rate of breathing
Q6 an impairment of the language aspect of speech
Questions 7–
Directions: For each of the questions below, ONE or MORE of the
responses is (are) correct. Decide which of the responses is
(are) correct. Then choose:
A o if 1, 2 and 3 are correct
B o if 1 and 2 only are correct
C o if 2 and 3 only are correct
D o if 1 only is correct
E o if 3 only is correct
2 Test 1: Questions
Directions summarised A B C D E 1, 2, 3 1, 2 only 2, 3 only 1 only 3 only
Q13 Creatinine clearance:
1 o is an index used to measure glomerular filtration rate
2 o measurement involves a 24-hour urine collection
3 o measurement requires 24-hour monitoring of plasma
creatinine
Q14 Patients receiving isosorbide dinitrate should be advised that:
1 o occurrence of headaches tends to decrease with continued
therapy
2 o tablets should be discarded 8 weeks after opening the
container
3 o tablets should be stored in glass containers
Q15 Adrenaline:
1 o is used in cardiac arrest
2 o administration requires monitoring of blood pressure
3 o results in a fall in blood pressure
Q16 Methadone:
1 o requires multiple dosing in a day
2 o is addictive
3 o is an opioid agonist
Q17 Patients receiving tamoxifen should be advised:
1 o that hot flushes may occur
2 o that menstrual irregularities may occur
3 o to report sudden breathlessness and any pain in the calf
Q18 Parenteral sodium bicarbonate:
1 o raises blood pH
2 o is indicated in metabolic acidosis
3 o may be used in hypomagnesaemia
4 Test 1: Questions
Q19 Phytomenadione:
1 o is a lipid-soluble analogue of vitamin K
2 o promotes hepatic synthesis of active prothrombin
3 o is indicated in babies at birth to prevent vitamin K deficiency
bleeding
Q20 Enoxaparin:
1 o cannot be used at the same dose as heparin
2 o thrombocytopenia may occur with its use
3 o agents that affect haemostasis should be used with care
Q21 Patients receiving oral isotretinoin should be advised:
1 o to avoid pregnancy
2 o to avoid wax epilation during treatment
3 o to use a lip balm regularly
Q22 A patient who will be undergoing a colonoscopy is advised to:
1 o use a topical haemorrhoid preparation before admission
2 o take a bowel cleansing preparation
3 o avoid solid food on previous day
Q23 In which of the following cases is referral recommended:
1 o a paediatric patient with a history of asthma who presents
with a chest infection
2 o a patient receiving diuretics who presents with symptoms of
a heat stroke
3 o a tourist who presents with acute diarrhoea
Questions 7–26 5
Q27 Signs and symptoms of pulmonary oedema include:
1 o weight loss
2 o dyspnoea
3 o cough
A o 1, 2, 3
B o 1, 2 only
C o 2, 3 only
D o 1 only
E o 3 only
Q28 Precipitants of acute pulmonary oedema include:
1 o hypothyroidism
2 o excessive infusion rate
3 o heart failure
A o 1, 2, 3
B o 1, 2 only
C o 2, 3 only
D o 1 only
E o 3 only
Q29 Parameters that are monitored during metolazone therapy include:
1 o body weight
2 o electrolytes
3 o LFTs
A o 1, 2, 3
B o 1, 2 only
C o 2, 3 only
D o 1 only
E o 3 only
Questions 27–80 7
Q30 Metolazone and bumetanide:
A o reduce the blood volume
B o produce a euphoric state
C o cause sedation
D o control bronchospasm
E o prevent embolisation
Q31 When PS is stabilised, the therapeutic plan should consider:
1 o stopping metolazone treatment
2 o changing bumetanide to an oral formulation
3 o starting co-amoxiclav
A o 1, 2, 3
B o 1, 2 only
C o 2, 3 only
D o 1 only
E o 3 only
Questions 32–38 involve the following case:
8 Test 1: Questions
CA is a 77-year-old patient who is admitted to hospital with infected multiple sores and who is complaining of polyuria and weakness. CA presented with reduced skin turgor, dehydration, tremor and in a confused state. CA has a past medical history of diabetes. Her general practitioner has started her the day before on ciprofloxacin 250 mg bd and fusidic acid cream bd. Diabetes was managed through dietary control and CA was not taking antidiabetic drugs. On admission, CA is started on: glibenclamide 2.5 mg daily ciprofloxacin 500 mg bd sodium chloride 0.9% iv infusion haloperidol 0.5 mg bd On admission: random blood glucose level 12 mmol/l blood pressure 125/78 mmHg
Q35 Pharmacist intervention with regards to therapy started on admission
includes:
1 o increase dose of ciprofloxacin
2 o review sodium chloride infusion
3 o rationale for haloperidol treatment
A o 1, 2, 3
B o 1, 2 only
C o 2, 3 only
D o 1 only
E o 3 only
Q36 As regards glibenclamide therapy:
A o gliclazide is preferred in this patient
B o the dose could be increased to 10 mg daily
C o the drug is administered in the afternoon
D o the drug reduces insulin secretion
E o it restores beta-cell activity
Q37 When the patient is discharged, advice includes:
1 o consuming small, frequent regular meals
2 o taking glibenclamide regularly
3 o using fusidic acid cream daily
A o 1, 2, 3
B o 1, 2 only
C o 2, 3 only
D o 1 only
E o 3 only
10 Test 1: Questions
Q38 Onset of hypoglycaemia in CA could be precipated by:
1 o missed doses of glibenclamide
2 o excess dietary intake
3 o skipped meals
A o 1, 2, 3
B o 1, 2 only
C o 2, 3 only
D o 1 only
E o 3 only
Questions 39–41 involve the following case:
Q39 Symptoms that could occur due to promethazine overdose include:
1 o drowsiness
2 o headache
3 o blurred vision
A o 1, 2, 3
B o 1, 2 only
C o 2, 3 only
D o 1 only
E o 3 only
Questions 27–80 11
BD is a 34-year-old patient admitted with an overdose of promethazine and alcohol withdrawal symptoms. Patient has a history of alcohol abuse.
Q43 Side-effects to be expected with simvastatin include:
1 o headache
2 o nausea
3 o abdominal pain
A o 1, 2, 3
B o 1, 2 only
C o 2, 3 only
D o 1 only
E o 3 only
Q44 Recommendations made to MB include:
1 o follow moderate exercise
2 o adopt a low-fat diet
3 o take atenolol 2 h before simvastatin
A o 1, 2, 3
B o 1, 2 only
C o 2, 3 only
D o 1 only
E o 3 only
Questions 45–47 involve the following case:
Questions 27–80 13
GD is a 72-year-old female whose current medication is: aspirin 75 mg daily dipyridamole 100 mg tds timotol 0.5% both eyes 2 drops bd lactulose 20 ml daily
Q45 Dipyridamole:
1 o cannot be used in combination with low-dose aspirin
2 o is used for prophylaxis of thromboembolism
3 o may cause increased bleeding during or after surgery
A o 1, 2, 3
B o 1, 2 only
C o 2, 3 only
D o 1 only
E o 3 only
Q46 Lactulose:
1 o dose needs to be reviewed as the maximum adult daily dose
is 5 ml
2 o should not be used for more than 5 days
3 o is used to maintain bowel evacuation
A o 1, 2, 3
B o 1, 2 only
C o 2, 3 only
D o 1 only
E o 3 only
Q47 GD is receiving medications for:
1 o glaucoma
2 o diarrhoea
3 o osteoporosis
A o 1, 2, 3
B o 1, 2 only
C o 2, 3 only
D o 1 only
E o 3 only
14 Test 1: Questions
Q50 Monitoring required because of spironolactone treatment involves:
1 o serum creatinine
2 o serum potassium
3 o thyroid function
A o 1, 2, 3
B o 1, 2 only
C o 2, 3 only
D o 1 only
E o 3 only
Q51 Losartan:
1 o is an angiotensin-II receptor antagonist
2 o exhibits a lower incidence of cough as a side-effect
compared with enalapril
3 o dose may be increased to 50 mg daily
A o 1, 2, 3
B o 1, 2 only
C o 2, 3 only
D o 1 only
E o 3 only
Q52 Digoxin is used in patients with heart failure:
1 o because it decreases myocardial intracellular ionic calcium
2 o when there is atrial fibrillation
3 o because it exerts a positive inotropic effect
A o 1, 2, 3
B o 1, 2 only
C o 2, 3 only
D o 1 only
E o 3 only
16 Test 1: Questions
Q53 Parameters to be monitored when digoxin therapy is started:
1 o plasma digoxin concentration
2 o plasma potassium measurement
3 o plasma sodium measurement
A o 1, 2, 3
B o 1, 2 only
C o 2, 3 only
D o 1 only
E o 3 only
Questions 54–57 involve the following case:
Q54 The likely diagnosis for LB is:
A o prickly heat
B o herpes zoster infection
C o herpes labialis infection
D o cytomegalovirus infection
E o hepatitis B infection
Q55 Patient should be advised:
1 o to take doses at regular intervals
2 o to avoid exposure to sunlight
3 o to wash hands thoroughly after drug administration
Questions 27–80 17
LB is a 55-year-old male patient who developed vesicles unilaterally around his waist. LB complained of a stabbing irritation in the area. LB is prescribed aciclovir 800 mg five times daily for 5 days.
Questions 58–63 involve the following case:
Q58 Penicillin G is:
A o phenoxymethylpenicillin
B o benzylpenicillin
C o penicillin V
D o piperacillin
E o pivmecillinam
Q59 Penicillin G is available in 600 mg vials. How many vials are required
for each dose?
A o 0.
B o 1
C o 2
D o 3
E o 30
Q60 Penicillin G:
1 o is bacteriostatic
2 o is bactericidal
3 o can be given as an intramuscular injection
A o 1, 2, 3
B o 1, 2 only
C o 2, 3 only
D o 1 only
E o 3 only
Questions 27–80 19
AD is a 39-year-old female with bacterial endocarditis. She is started on gentamicin 80 mg iv twice daily and penicillin G iv 1.8 g every 6 h.
Q61 Gentamicin:
1 o has a broad spectrum of activity
2 o is contraindicated in hepatic impairment
3 o therapy may be changed to oral administration when the
patient is stabilised
A o 1, 2, 3
B o 1, 2 only
C o 2, 3 only
D o 1 only
E o 3 only
Q62 A possible reason for these symptoms is:
1 o allergy to gentamicin
2 o allergy to penicillin G
3 o development of heat rash
A o 1, 2, 3
B o 1, 2 only
C o 2, 3 only
D o 1 only
E o 3 only
Q63 Manifestations of bacterial endocarditis include:
1 o prolonged fever
2 o embolic phenomena
3 o renal failure
20 Test 1: Questions
Patient developed a rash and started complaining of generalised itch after the administration of the drugs.
