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CPIA EXAM CERTIFIED PROFESSIONAL IN
IACUC ADMINISTRATION EXAM QUESTIONS
AND CORRECT ANSWERS (VERIFIED
ANSWERS) | ALREADY GRADED A+ | LATEST
EXAM (JUST RELEASED)
Which of the following statements is true of barbiturates? a) Barbiturates cause the animal to gasp for air before becoming unconscious indicating some pain and distress. b) These drugs are extremely painful when administered outside the vein. c) Barbiturates break down quickly in the body so that carcasses of animals in which barbiturates were used for anesthesia do not represent a threat to predators which may eat them. d) Pentobarbital is a barbiturate that is not classified as a controlled substance. ------ CORRECT ANSWER---------------b) These drugs are extremely painful when administered outside the vein. Source: AALAS Learning Library Regulatory and IACUC Compliance Track > US Mandates and Guidelines > Euthanasia of Research Animals: AVMA Guidelines Which of the following statements regarding physical methods of euthanasia is true? a) There are few aesthetic considerations for this form of euthanasia. b) Physical methods of euthanasia may be the most humane method for relieving pain and suffering in some instances. c) Physical methods of euthanasia always cause more distress for the animal. d) Exsanguination, stunning, and pithing are acceptable physical methods of euthanasia for horses and cattle. ------CORRECT ANSWER---------------b) Physical methods of euthanasia may be the most humane method for relieving pain and suffering in some instances. Source: AALAS Learning Library Regulatory and IACUC Compliance Track > US Mandates and Guidelines > Euthanasia of Research Animals: AVMA Guidelines"
In special circumstances that may indicate a need to deviate from the AVMA guidelines, what should be the deciding factor? a) The cost of the procedure b) The best interest of the animal c) The decision of the IO d) Expediency of the method ------CORRECT ANSWER---------------b) The best interest of the animal Source: AALAS Learning Library Regulatory and IACUC Compliance Track > US Mandates and Guidelines > Euthanasia of Research Animals: AVMA Guidelines" Cervical dislocation should not be performed in rabbits weighing more than: a) 500 g. b) 2 kg. c) 800 g. d) 1 kg. ------CORRECT ANSWER---------------d) 1 kg. Source: AALAS Learning Library Regulatory and IACUC Compliance Track > US Mandates and Guidelines > Euthanasia of Research Animals: AVMA Guidelines Which of the following statements is true about the use of carbon monoxide for euthanasia? a) Acceptable for individual or mass euthanasia of cattle, horses, and other large mammals. b) It is extremely stressful to the animal. c) Death occurs rapidly at concentrations of 4 to 6%. d) This agent is safe to use by human operators. ------CORRECT ANSWER--------------- c) Death occurs rapidly at concentrations of 4 to 6%. Source: AALAS Learning Library Regulatory and IACUC Compliance Track > US Mandates and Guidelines > Euthanasia of Research Animals: AVMA Guidelines Confirmation of death is determined by:
Euthanasia agents that act by way of hypoxia are not recommended for which of the following groups of animals? a) Warm-blooded neonates b) Ruminants c) Older animals of most species d) Animals with respiratory problems ------CORRECT ANSWER---------------a) Warm- blooded neonates Source: AALAS Learning Library Regulatory and IACUC Compliance Track > US Mandates and Guidelines > Euthanasia of Research Animals: AVMA Guidelines" Which of the following statements is true about inhalant agents used for euthanasia? a) Since inhalant anesthetic effects are specific to the animal species being euthanized, no special precautions for personnel are required. b) Due to their small size, inhalants provide a quick euthanasia method for neonatal animals. c) Using a low concentration of inhalation agent is the preferred method to conduct euthanasia procedures. d) Animals should be protected from contact with the liquid form of the anesthetic agent. ------CORRECT ANSWER---------------d) Animals should be protected from contact with the liquid form of the anesthetic agent. Source: AALAS Learning Library Regulatory and IACUC Compliance Track > US Mandates and Guidelines > Euthanasia of Research Animals: AVMA Guidelines" Which of the following statements is true when using CO2 for euthanasia? a) It is best to combine carbon dioxide with oxygen for euthanasia. b) Pulmonary lesions may occur if the carbon dioxide concentration reaches 40%. c) The optimal flow rate is one that displaces 10% of the chamber volume every minute. d) Gas flow should be maintained for at least 1 minute after apparent death to make sure the animal does not recover. ------CORRECT ANSWER---------------d) Gas flow should be maintained for at least 1 minute after apparent death to make sure the animal does not recover.
Source: AALAS Learning Library Regulatory and IACUC Compliance Track > US Mandates and Guidelines > Euthanasia of Research Animals: AVMA Guidelines Immersing aquatic species in a bath saturated with carbon dioxide is an acceptable euthanasia method. a) True b) False ------CORRECT ANSWER---------------a) True Source: AALAS Learning Library Regulatory and IACUC Compliance Track > US Mandates and Guidelines > Euthanasia of Research Animals: AVMA Guidelines" Which of the following statements concerning euthanasia is incorrect? a) Physical methods of euthanasia are most desirable when used on conscious animals. b) When used alone, non-physical methods of euthanasia are usually preferred over physical methods. c) Physical methods of euthanasia are most desirable when used on anesthetized animals. d) The investigator must provide a scientific justification to the IACUC if a physical method will be used alone. ------CORRECT ANSWER---------------a) Physical methods of euthanasia are most desirable when used on conscious animals. Source: AALAS Learning Library Regulatory and IACUC Compliance Track > US Mandates and Guidelines > Euthanasia of Research Animals: AVMA Guidelines Chloral hydrate is conditionally acceptable for use in large animals that: a) are already sedated. b) cannot be easily restrained. c) will have an adjunctive method of euthanasia following the injection of chloral hydrate. d) None of the above ------CORRECT ANSWER---------------a) are already sedated. Source: AALAS Learning Library
Regulatory and IACUC Compliance Track > US Mandates and Guidelines > Occupational Health and Safety in the Care and Use of Research Animal" Which of the following statements is false concerning shigellosis? a) Very large numbers of organisms are required to produce an infection. b) Transmission is fecal-oral. c) Clinical signs include acute bloody diarrhea. d) Nonhuman primates are the only important reservoir in an animal facility. ------ CORRECT ANSWER---------------a) Very large numbers of organisms are required to produce an infection Source: AALAS Learning Library Regulatory and IACUC Compliance Track > US Mandates and Guidelines > Occupational Health and Safety in the Care and Use of Research Animals" The effectiveness of the autoclave can be monitored by using: a) Paper strips or vials containing bacterial spores b) Agar plates inoculated with viruses c) Agar plates inoculated with DNA fragments d) Vials of pH paper e) All of the above f) None of the above ------CORRECT ANSWER---------------a) Paper strips or vials containing bacterial spores Source: AALAS Learning Library Regulatory and IACUC Compliance Track > US Mandates and Guidelines > Occupational Health and Safety in the Care and Use of Research Animals Which of the following are in a unique position to monitor the daily effectiveness of and compliance with health and safety procedures in a laboratory animal program? a) Principal investigators b) Animal care staff c) IACUC chairperson d) Research technicians ------CORRECT ANSWER---------------b) Animal care staff Source: AALAS Learning Library
Regulatory and IACUC Compliance Track > US Mandates and Guidelines > Occupational Health and Safety in the Care and Use of Research Animals" Which of the following statements is true concerning dermatomycosis? a) Infected animals usually have several obvious lesions. b) One species of dermatophyte is common in animal facilities. c) Spores readily degrade in the environment. d) None of the above ------CORRECT ANSWER---------------d) None of the above Source: AALAS Learning Library Regulatory and IACUC Compliance Track > US Mandates and Guidelines > Occupational Health and Safety in the Care and Use of Research Animals" Which of the following is not an effective means of identifying hazards? a) Consulting personnel from governmental agencies (e.g., NIH, CDC, OSHA) b) Considering only those hazards that previously caused obvious illness or injury c) Having environmental health and safety professionals tour the animal facility d) Relying on experiences from other institutions, professional associations, or societies ------CORRECT ANSWER---------------b) Considering only those hazards that previously caused obvious illness or injury Source: AALAS Learning Library Regulatory and IACUC Compliance Track > US Mandates and Guidelines > Occupational Health and Safety in the Care and Use of Research Animals How often should biological safety cabinets be certified? a) At the time of the IACUC inspection b) When installed c) At least monthly d) At least once a year ------CORRECT ANSWER---------------d) At least once a year Source: AALAS Learning Library Regulatory and IACUC Compliance Track > US Mandates and Guidelines > Occupational Health and Safety in the Care and Use of Research Animals
D. change in fluid administration ------CORRECT ANSWER---------------C. change in anesthetic agent Which of the following entities are required to release information per the Freedom of Information Act? A. OLAW B. AAALAC C. IACUC D. HSUS ------CORRECT ANSWER---------------A. OLAW Training and instruction of personnel must include guidance in which of the following areas? A. Effective writing of animal use proposals B. Proper use of personal protective equipment C. Appropriate communication with animal activist groups D. Research or testing methods that limit the use of animals ------CORRECT ANSWER- --------------D. Research or testing methods that limit the use of animals Which of the following procedures may correctly be applied to Designated Member Review? A. The IACUC Chair appoints one member to do the Designated Member Review. B. The designated member reviewer is authorized to approve, require modifications, or disapprove the proposal. C. All members receive information about the proposal and send their votes to the designated member reviewer for tallying. D. Designated member review may be utilized to review proposals when there is insufficient time to notify the full membership of the proposal details. ------CORRECT ANSWER---------------A. The IACUC Chair appoints one member to do the Designated Member Review. In which of the following circumstances may animal work begin before receipt of IACUC approval? A. It is a continuing study awaiting three year renewal and for which the renewal protocol has been submitted to the IACUC. B. It is a small pilot study on non-AWAR species. C. It is a teaching activity that uses students' personally owned dogs and cats.
D. There are no circumstances in which animal work may begin before IACUC approval. ------CORRECT ANSWER---------------D. There are no circumstances in which animal work may begin before IACUC approval. Which of the statements below about the responsibility and authority of the Institutional Official (IO) is false? A. The IO must have authority to commit institutional resources in support of the animal care and use program. B. The IO must be the institution's Chief Executive Officer or some appointed by him with authority to fund resources. C. The IO may reinstate an animal activity that was previously suspended by the IACUC. D. The IO may suspend an animal activity that was previously approved by the IACUC. ------CORRECT ANSWER---------------C. The IO may reinstate an animal activity that was previously suspended by the IACUC. With regard to conducting official IACUC business, the definition of a quorum is: A. More than fifty percent (a majority) of voting members. B. Fifty percent of voting and non-voting members combined. C. More than fifty percent (a majority) of voting and non-voting members combined. D. Fifty percent of the voting members. ------CORRECT ANSWER---------------A. More than fifty percent (a majority) of voting members The proper sequence for a designated member review by the IACUC is: A. Review materials are sent to all voting members, full committee review is not requested by any member, the chairperson assigns one or more IACUC members as designated reviewers. B. Review materials are sent to a quorum of designated reviewers, review results are solicited from designated reviewers, full committee approval of results is requested. C. Review materials are sent to all voting members, a majority of members do not request full committee review, the chairperson assigns one or more IACUC members as designated reviewers. D. Review materials are sent to a quorum of voting members, a majority of a quorum does not request full committee review, the chairperson assigns one or more IACUC members as designated reviewers. ------CORRECT ANSWER---------------A. Review materials are sent to all voting members, full committee review is not requested by any member, the chairperson assigns one or more IACUC members as designated reviewers.
Which of the following institutions must follow the PHS Policy? A. Institutions that use any animals for research, teaching, or testing. B. Institutions that use vertebrate animals for research, teaching, or testing. C. Institutions that accept USDA research funds. D. Institutions that accept PHS funding. ------CORRECT ANSWER---------------D. Institutions that accept PHS funding. The three Rs of Russell and Burch stand for what? A. Research, refinement, and recovery. B. Replace, recognize, and recover. C. Replacement, reduction, and refinement. D. Research, results, and review. ------CORRECT ANSWER---------------C. Replacement, reduction, and refinement. What is a primary mission of the Animal Welfare Information Center (AWIC)? A. Publishes the Animal Welfare Act Regulations and Standards. B. Provides assistance with alternatives and database searches. C. Publishes the Guide for the Care and Use of Laboratory Animals. D. Provides assistance with identifying the best laboratory animal cage washing equipment. ------CORRECT ANSWER---------------B. Provides assistance with alternatives and database searches. Which agency requires an annual report of the number of animals used by pain/distress category? A. American Association for Laboratory Animal Science B. Association for Assessment and Accreditation of Laboratory Animal Care C. Office of Laboratory Animal Welfare D. United States Department of Agriculture ------CORRECT ANSWER---------------D. United States Department of Agriculture Regarding studies with infectious agents in animals, as the BSL and ABSL number increases from 1 to 4, what happens to the containment and safeguard practices? A. They become less important. B. They become less stringent. C. They become more vague.
D. They become more stringent. ------CORRECT ANSWER---------------D. They become more stringent. U.S. Government Principles on the Use of Animals in Research state that: A. Relief of pain should be provided for vertebrate animals except for birds, mice and rats. B. Animals will show evidence of pain if a procedure causes them pain. C. Pain is perceived differently by animals than by humans. D. Procedures that are painful to humans should be assumed to cause pain in animals unless there is evidence to the contrary. ------CORRECT ANSWER---------------D. Procedures that are painful to humans should be assumed to cause pain in animals unless there is evidence to the contrary. Which of the statements below about the responsibility and authority of the Institutional Official (IO) is false? A. The IO must have authority to commit institutional resources in support of the animal care and use program. B. If the IO is not the institution's Chief Executive Officer, then the CEO must delegate IO authority to that person in writing. C. The IO may reinstate an animal activity that was previously suspended by the IACUC. D. The IO may suspend an animal activity that was previously approved by the IACUC. ------CORRECT ANSWER---------------C. The IO may reinstate an animal activity that was previously suspended by the IACUC. PHS policy states that the OLAW requires assurance renewal every: a) three years b) up to five years c) four years d) depends on the institution and program size ------CORRECT ANSWER---------------b) up to five years The guide incorporated two must to Diaster Planning and Emergency Prepardness which involved: a) triage plans for personnel and animals b) emergency contacts for all researchers and staff c) plans include satellite facilities d) corrdinated by the institutional official
a) Formal orientation to the institution's program b) Training by a certified veterinarian on all procedures involving animals c) Training on how to review protocols as well as evaluate the program d) Training on how to inspect facilities and labs where animal use or housing occurs e) Training on legislation, regulations, guidelines, and policies ------CORRECT ANSWER---------------b) Training by a certified veterinarian on all procedures involving animals Which of the following is not required for IACUC membership according to the Ag Guide: a. veterinarian with training or experience in laboratory animal science and medicine b. scientist with training or experience in agricultural animals c. a person whose primary concerns are in an area outside of science d. a person who is not affiliated with the institution ------CORRECT ANSWER--------------- a. veterinarian with training or experience in laboratory animal science and medicine USDA Regulations require the following IACUC members:
- Veterinarian, chair, nonaffiliated
- Veterinarian, chair, scientist
- Veterinarian, nonaffiliated, scientist
- Veterinarian, nonaffiliated, nonscientist ------CORRECT ANSWER---------------1. Veterinarian, chair, nonaffiliated PHS Policy requires the following IACUC members:
- Veterinarian, chair, nonscientist, nonaffiliated
- Veterinarian, chair, nonaffiliated, scientist
- Veterinarian, nonaffiliated, scientist, nonscientist
- Veterinarian, nonaffiliated, nonscientist, statistician ------CORRECT ANSWER---------- -----3. Veterinarian, nonaffiliated, scientist, nonscientist PHS and AWRs state that all records should be kept for a minimum of: a) indefinate b) 1-2 years c) 3 years d) non of the above ------CORRECT ANSWER---------------c) 3 years
PHS institutional Assurance is approve up to ___ years where as USDA registration is updated every ___ years: a) 3yrs PHS and 5 years USDA b) up to 5 years for PHS and 3 years FOR USDA c) up to 5 years for both d) 3 years for both ------CORRECT ANSWER---------------b) up to 5 years for PHS and 3 years FOR USDA Which is not required when filing a PHS Institutional Assurance: a) dates of facility inspections b) IACUC member roster c) Number of covered species used annually d) Lines of authority e) species housed and average daily inventory by species ------CORRECT ANSWER---- -----------c) Number of covered species used annually If the institution is PHS assured and is not AAALAC accredited, what must be included in the annual report to OLAW? a) The IACUC minutes b) The intituional officals assurance statement c) Semiannual IACUC report d) none of the above ------CORRECT ANSWER---------------c) Semiannual IACUC report What are the two circumstances that you would submit a semiannual report to OLAW? - -----CORRECT ANSWER---------------At the request of OLAW or if your institutional is not assured by a accrediting body such as AAALAC What line of authority submits the annual report to OLAW? ------CORRECT ANSWER--- ------------The IO Where do you send the USDA annual report? ------CORRECT ANSWER--------------- APHIS AC Regional Director.
True or False. DoD Activities performed or sponsored in foreign countries shall follow all applicable US requirements, as well as regulations and standards of the host country. -- ----CORRECT ANSWER---------------True True or False. The non-affiliated member(s) on a DoD IACUC may be a federal employee with demonstrated commitment to the community. - -----CORRECT ANSWER- --------------True True or False. DoD organizations/facilities are not required to apply for AAALAC accreditation. ------CORRECT ANSWER---------------False True or False. Violation complaints within the DoD can only be reported to the Inspector General. ------CORRECT ANSWER---------------False True or False. The Department of Defense directive indicates that any species may be purchased or used for inflicting wounds from any type of weapon to conduct training in surgical/medical treatment procedures. ------CORRECT ANSWER---------------False True or False. The Joint Technical Working Group (JTWG) acts as a central advisory committee to the Armed Services Biomedical Research Evaluation and Management (ASBREM) Committee. ------CORRECT ANSWER---------------True The Executive Agent designates the Commander of the US Army Veterinary Command, the Director of Veterinary Services Activity, the Director of Defense Research and Engineering and: a. The Chair of the Joint Technical Working Group (JTWG) b. A veterinarian to the Interagency Research Animal Committee c. The office that will perform headquarters-level administrative review of the use of non-human primates. d. None of the above e. All of the above ------CORRECT ANSWER---------------d. None of the above
Which of the following are applicable to the Department of Defense: a. Animal Welfare Act; Animal Welfare Regulations b. The Guide for the Care and Use of Laboratory Animals; The Guide for the Care and Use of Agricultural Animals in Agricultural Research and Teaching c. The Lacey Act; Marine Mammal Protection Act; Endangered Species Act; Convention on International Trade in Endangered Species of Wild Fauna and Flora d. A & C e. All of the above ------CORRECT ANSWER---------------e. All of the above The Executive Agent for the Department of Defense Directive number 3216.1 is the
a. Director, Defense Research and Engineering b. Secretary of the Army c. Commander, US Army Veterinary Command d. Inspector General e. Under Secretary of Defense for Acquisition and Technology ------CORRECT ANSWER---------------b. Secretary of the Army According to the 8th edition of the Guide each institution must or should have an occupational health program in place consistent with federal, state and local regulations? a) must b) should c) a and b d) none of the above ------CORRECT ANSWER---------------a) must True or False: Institution procuring animal must have lawful procedures in place as well as procedures for compliance with animal transportation regulations to include international requirements. ------CORRECT ANSWER---------------True Programs for medical evaluation preventative medicine include all the following except: a) pre-employment evaluation b) health history c) procedures for reporting and treating injuries and allergies, including bites and accidents d) Zoonosis surveillance e) Institutions must consider confidentiality and other legal factors f) Pre-employment serum samples
