curriculum of molecular biology bs 4 years programme (2016), Study notes of Molecular biology

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CURRICULUM

OF

MOLECULAR BIOLOGY

BS 4 YEARS PROGRAMME

HIGHER EDUCATION COMMISSION

ISLAMABAD

CURRICULUM DIVISION, HEC

Prof. Dr. Mukhtar Ahmed Chairman, HEC

Mr. Fida Hussain Director General (Acad)

Ms. Ghayyur Fatima Director (Curri)

Mr. Rizwan Shoukat Deputy Director (Curri)

Mr. Abid Wahab Assistant Director (Curri)

Mr. Riaz-ul-Haque Assistant Director (Curri)

PREFACE

The curriculum, with varying definitions, is said to be a plan of the teaching- learning process that students of an academic programme are required to undergo. It includes objectives & learning outcomes, course contents, scheme of studies, teaching methodologies and methods of assessment of learning. Since knowledge in all disciplines and fields is ]]]]]]expanding at a fast pace and new disciplines are also emerging; it is imperative that curricula be developed and revised accordingly.

University Grants Commission (UGC) was designated as the competent authority to develop, review and revise curricula beyond Class-XII vide Section 3, Sub-Section 2 (ii), Act of Parliament No. X of 1976 titled “Supervision of Curricula and Textbooks and Maintenance of Standard of Education”. With the repeal of UGC Act, the same function was assigned to the Higher Education Commission (HEC) under its Ordinance of 2002, Section 10, Sub-Section 1 (v).

In compliance with the above provisions, the Curriculum Division of HEC undertakes the revision of curricula after every three years through respective National Curriculum Revision Committees (NCRCs) which consist of eminent professors and researchers of relevant fields from public and private sector universities, R&D organizations, councils, industry and civil society by seeking nominations from their organizations.

In order to impart quality education which is at par with international standards, HEC NCRCs have developed unified templates as guidelines for the development and revision of curricula in the disciplines of Basic Sciences, Applied Sciences, Social Sciences, Agriculture and Engineering in 2007 and

It is hoped that this curriculum document, prepared by the respective NCRC’s, would serve the purpose of meeting our national, social and economic needs, and it would also provide the level of competency specified in Pakistan Qualification Framework to make it compatible with international educational standards. The curriculum is also placed on the website of HEC http://hec.gov.pk/english/services/universities/RevisedCurricula/Pages/default.aspx

(Fida Hussain)

Director General (Academics)

CURRICULUM DEVELOPMENT PROCESS

STAGE-I STAGE-II STAGE-III STAGE-IV

CURRI. UNDER CONSIDERATION

CURRI. IN DRAFT STAGE

FINAL STAGE FOLLOW UP STUDY

COLLECTION OF REC

APPRAISAL OF 1ST DRAFT BY EXP. OF COL./UNIV

PREP. OF FINAL CURRI.

QUESTIONNAIRE

CONS. OF CRC. FINALIZATION OF DRAFT BY CRC

INCORPORATION OF REC. OF V.C.C.

COMMENTS

PREP. OF DRAFT BY CRC

APPROVAL OF CURRI.BY V.C.C.

PRINTING OF CURRI.

REVIEW

IMPLE.OF CURRI. BACK TO STAGE-I

ORIENTATION COURSES

Abbreviations Used: CRC. Curriculum Revision Committee VCC. Vice Chancellor’s Committee EXP. Experts COL. Colleges UNI. Universities PREP. Preparation REC. Recommendations

8. Dr. Shahid Raza, Dean / Director, Department of Biological Sciences, University of South Asia, 47 Tufail Road, Lahore.

Member

9. Prof. Dr. Ghulam Asghar Maka, Professor (Director), Institute of Microbiology, University of Sindh, Jamshoro.

Member

10. Dr. Mir Muhammad Ali Talpur, Associate Professor, Department of Microbiology, Shah Abdul Latif University, Khairpur.

Member

11. Dr. Ali Muhammad Waryah, Assistant Professor, Department of Molecular Biology & Human Genetics, Liaquat University of Medical & Health Sciences, Jamshoro, Sindh.

Member

12. Dr. Shahid Ali, Assistant Professor, Centre for Biodiversity & Microbiology, University of Swat, G. T. Road, Odigram, Swat

Member

13. Dr. Hamid Manzoor, Assistant Professor, Institute of Molecular Biology & Biotechnology, Bahauddin Zakariya University, Multan.

Member

14. Dr. Bushra Rashid, Assistant Professor, Centre of Excellence in Molecular Biology (CEMB), University of the Punjab, Lahore.

Member

15. Dr. Deeba Noreen Baig, Assistant Professor, Department of Biological Sciences, Forman Christian College, Ferozpur Road, Lahore.

Member

16. Dr. Muhammad Qasim, Assistant Professor, Department of Microbiology, Kohat University of Science & Technology, Kohat.

Member/ Secretary

Objectives of the meeting:

● To develop the draft curriculum in the discipline of Molecular Biology and to bring it par with international standards. ● To incorporate latest reading and writing material against each course. ● To bring uniformity and develop minimum baseline courses in each and every course of study. ● To make recommendations for promotion/development of the discipline.

The meeting started with the recitation of verses from the Holy Quran by Dr. Muhammad Qasim. Ms. Ghayyur Fatima (Director Curriculum) presided over the inaugural session. She welcomed the participants on behalf of HEC and thanked the participants for attending the meeting for this cause of national significance. Ms. Ghayyur Fatima also highlighted brief history of semester system implementation in Pakistan. She also briefed about the role of HEC in strengthening the curriculum of Molecular Biology and to bring it at par with international standards. Furthermore, she encourages the participants to prepare their suggestions and recommendations for HEC to bring improvement in current semester system.

The committee unanimously agreed upon selecting Prof. Dr. Anjum Nasim Sabri as Convener and Dr. Muhammad Qasim as Secretary of the NCRC in Molecular Biology. Ms. Ghayyur Fatima requested the convener of the committee to start technical session in accordance with the agenda. Prof. Dr. Anjum Nasim Sabri briefed the committee about the background of Molecular Biology degree programme and its importance in biology to meet the demand of local market. She asked the committee members to give their input in the document to be drafted at the end of the meeting. It was decided that the general courses, courses from other departments will be same with reference to contents to already approved HEC curriculum of biological sciences. It is necessary to maintain equity with reference to first two years.

The committee went through the scheme of study for 4-year BSc. (Hons) Molecular Biology programme at structural level and reviewed its courses and credit hours. Molecular Biology degree programmes of some of international universities such as Cornell, King’s college, London; University of Birmingham, The University of Sheffield and Maxwell were also discussed so that our syllabi meet international standards. Following extensive brain storming and constructive criticism a list of compulsory, general, foundation, major and elective courses were prepared. These courses were then arranged in various semesters according to its relevancy and in-line sequence. Prof. Dr. Bushra raises issues related to BS (2 years) degree and courses requirement for admission in BS (4 years) Molecular Biology and it was decided that concerned body of the university will adopt its own criteria for admission and pre-requisite courses. The forum also decided to add foreign language and comparative religion as an optional compulsory course.

FRAME WORK FOR BS MOLECULAR BIOLOGY

(4 YEARS PROGRAMME)

Total numbers of Credit hours 136 Duration 4 years Semester duration 16-18 weeks Semesters 08 Course Load per Semester 15-18 Cr hr Number of courses per semester 4-6 (not more than 3 lab / practical courses)

Compulsory courses requirements (the student has no choice)

General courses to be chosen from other departments

Discipline specific foundation Courses

9 courses 9 courses 10 - 11 courses Subject Cr Hr

Subject (^) Cr. Hr

Subject Cr. Hr

1. English I
2. English II
3. English III / Communication skills
4. English IV/ Foreign language
5. Pakistan Studies
6. Islamic Studies / Ethics/ Comparative Religion
7. Mathematics I
8. Biostatistics/Mat hematics II
9. Introduction to Computer Note* Note**

3 3 3 3 2 2 3 3

2+

1. General Genetics
2. Biodiversity of animals
3. Biodiversity of plants
4. Biochemistry-I
5. Biochemistry-II
6. Microbiology
7. Cell Biology
8. Animal Physiology
9. Plant Physiology
10. Chemistry
11. Ecology and Ecosystem
12. Developmental Biology
13. Endocrinology
14. Sociology/Arts/ Environmental current issues/ Environmental ethics
15. Entrepreneurship Note***

2+ 2+

2+ 2+ 2+ 2+ 2+ 2+ 2+ 2+ 2+

2+

2+ 2+ 0

1. Molecular Biology-I
2. Molecular Biology-II
3. Molecular Genetics
4. *Immunology
5. **Virology
6. Molecular Ecology
7. Bioinformatics
8. Basic techniques in Molecular Biology
9. Enzymology
10. Introduction to Omics
11. Biotechnology
12. Cell and tissue Culture
13. Biosafety and Bioethics

2+

2+

2+

2+ 2+ 2+

2+ 1+

2+ 2+

2+ 2+

2+

25 23 34

• University may recommend other General courses according to their available faculty and expertise. ** University may recommend any other course in lieu of Mathematics II. *** University may recommend other courses according to their available faculty i.e. Zoology, Botany, Biotechnology, Animal/Human/Plant Physiology, Chemistry/Biochemistry, Endocrinology, Ecology and

Ecosystem, Developmental Biology, Plant diversity and Genetics, Microbiology and Molecular Genetics.

---

• General Immunology ** General Virology

Major courses including research project/internship

Elective Courses within the major

11 - 13 courses 4 courses

Subject Cr. hr Subject Cr. hr

1. Advanced Techniques in Molecular Biology
2. Gene therapy
3. Cell signaling
4. Recombinant DNA technology
5. Molecular Evolution
6. Genomics
7. Transcriptomics
8. Proteomics
9. Molecules to the Market
10. Molecular Diagnostics
11. Quantitative Biology
12. Skills and Research Methodology
13. Immunogenetics
14. Molecular Toxicology
15. Molecular Pharmacology
16. Bionanotechnology
17. Research Project

Elective I Elective II Elective III Elective IV

**** Student may take 13 courses out of the list of 17 courses in major other than Research Project.

SCHEME OF STUDIES FOR BS MOLECULAR BIOLOGY

(4 YEARS PROGRAMME)

Semester/ year Name of subject Credits First ENGLISH-I 03 PAKISTAN STUDIES 02 MATH- I 03 GENERAL-I 2 + 1 GENERAL-II 2 + 1 FOUNDATION-I 2 + 1 17 Second ENGLISH-II 03 ISLAMIC STUDIES / ETHICS 02 MATH/STAT-II / UNIV. OPTIONAL

GENERAL-III 2 + 1

GENERAL-IV 2 + 1

FOUNDATION-II 2 + 1

Third COMPUTER APPLICATION 03 ENGLISH-III/COMMUNICATION SKILLS

GENERAL-V 2 + 1

GENERAL-VI 2 + 1

FOUNDATION-II 2 + 1

FOUNDATION-III 2 + 1

Fourth ENGLISH-IV/FOREIGN LANGUAGE UNIV. OPTIONAL

GENERAL-VII 2 + 1

GENERAL-VIII 2 + 1

FOUNDATION-IV 2 + 1

FOUNDATION-V 2 + 1

FOUNDATION-VI 2 +

Fifth FOUNDATION-VII 2 + 1 FOUNDATION-VIII 2 + 1 FOUNDATION-IX 2 + 1 MAJOR- I 2 + 1 MAJOR- II 2 + 1 MAJOR- III 2 + 1 18

Sixth FOUNDATION- X 2 + 1 MAJOR- IV 2 + 1 MAJOR- V 2 + 1 MAJOR- VI 2 + 1 MAJOR- VII 2 + 1 MAJOR-VIII 2 + 1 18 Seventh MAJOR- IX 2 + 1 MAJOR- X 2 + 1 ELECTIVE-I 2 + 1 ELECTIVE-II 2 + 1 ELECTIVE PAPER/ RESEARCH PROJECT

Eighth MAJOR- XI 2 + 1 MAJOR-XII 2 + 1 ELECTIVE-I 2 + 1 ELECTIVE-II 2 + 1 ELECTIVE PAPER /RESEARCH PROJECT

Total credit hours 136

List of Compulsory Courses:

1. English I
2. English II
3. English III/ Communication skills
4. English IV/ Foreign language
5. Pakistan Studies
6. Islamic Studies / Ethics /Comparative Religion
7. Mathematics I
8. Biostatistics/Mathematics II
9. Introduction to Computer

c) Reading/Comprehension

4. Reading. Upper Intermediate. Brain Tomlinson and Rod Ellis. Oxford Supplementary Skills. Third Impression 1992. ISBN 0 19 453402 2.

d) Speaking

ENGLISH II (COMMUNICATION SKILLS)

Credit Hrs 3+

Objectives: Enable the students to meet their real life communication

needs.

Course Contents:

Paragraph writing Practice in writing a good, unified and coherent paragraph Essay writing Introduction CV and job application Translation skills Urdu to English Study skills Skimming and scanning, intensive and extensive, and speed reading, summary and précis writing and comprehension Academic skills Letter/memo writing, minutes of meetings, use of library and internet Presentation skills Personality development (emphasis on content, style and pronunciation)

Note: documentaries to be shown for discussion and review

RECOMMENDED BOOKS:

Communication Skills

a) Grammar

1. Practical English Grammar by A. J. Thomson and A. V. Martinet. Exercises 2. Third edition. Oxford University Press 1986. ISBN 0 19 431350 6.

b) Writing

1. Writing. Intermediate by Marie-Christine Boutin, Suzanne Brinand and Francoise Grellet. Oxford Supplementary Skills. Fourth Impression 1993. ISBN 019 435405 7 Pages 45-53 (note taking).

2. Writing. Upper-Intermediate by Rob Nolasco. Oxford Supplementary Skills. Fourth Impression 1992. ISBN 0 19 435406 5 (particularly good for writing memos, introduction to presentations, descriptive and argumentative writing).

c) Reading

1. Reading. Advanced. Brian Tomlinson and Rod Ellis. Oxford Supplementary Skills. Third Impression 1991. ISBN 0 19 453403
2. Reading and Study Skills by John Langan
3. Study Skills by Richard York.

ENGLISH III (TECHNICAL WRITING AND

PRESENTATION SKILLS)

Objectives: Enhance language skills and develop critical thinking

Course Contents:

Presentation skills

Essay writing Descriptive, narrative, discursive, argumentative

Academic writing How to write a proposal for research paper/term paper

How to write a research paper/term paper (emphasis on style, content, language, form, clarity, consistency)

Technical Report writing

Progress report writing

Note: Extensive reading is required for vocabulary building

RECOMMENDED BOOKS:

Technical Writing and Presentation Skills

a) Essay Writing and Academic Writing

1. Writing. Advanced by Ron White. Oxford Supplementary Skills. Third Impression 1992. ISBN 0 19 435407 3 (particularly suitable for discursive, descriptive, argumentative and report writing).
2. College Writing Skills by John Langan. McGraw-Hill Higher Education. 2004.
3. Patterns of College Writing (4th^ edition) by Laurie G. Kirszner and Stephen R. Mandell. St. Martin’s Press.

2. Akbar, S. Zaidi. Issue in Pakistan’s Economy. Karachi: Oxford University Press, 2000.
3. S. M. Burke and Lawrence Ziring. Pakistan’s Foreign policy: An Historical analysis. Karachi: Oxford University Press, 1993.
4. Mehmood, Safdar. Pakistan Political Roots & Development. Lahore,
5. Wilcox, Wayne. The Emergence of Bangladesh, Washington: American Enterprise, Institute of Public Policy Research, 1972.
6. Mehmood, Safdar. Pakistan Kayyun Toota, Lahore: Idara-e-Saqafat-e- Islamia, Club Road, nd.
7. Amin, Tahir. Ethno - National Movement in Pakistan, Islamabad: Institute of Policy Studies, Islamabad.
8. Ziring, Lawrence. Enigma of Political Development. Kent England: Wm Dawson & sons Ltd, 1980.
9. Zahid, Ansar. History & Culture of Sindh. Karachi: Royal Book Company,
10. Afzal, M. Rafique. Political Parties in Pakistan, Vol. I, II & III. Islamabad: National Institute of Historical and cultural Research, 1998.
11. Sayeed, Khalid Bin. The Political System of Pakistan. Boston: Houghton Mifflin, 1967.
12. Aziz, K. K. Party, Politics in Pakistan, Islamabad: National Commission on Historical and Cultural Research, 1976.
13. Muhammad Waseem, Pakistan Under Martial Law, Lahore: Vanguard,
14. Haq, Noor ul. Making of Pakistan: The Military Perspective. Islamabad: National Commission on Historical and Cultural Research, 1993.

ISLAMIC STUDIES

Credit Hrs 3+

Objectives:

This course is aimed at: 1 To provide Basic information about Islamic Studies

2 To enhance understanding of the students regarding Islamic Civilization

3 To improve Students skill to perform prayers and other worships

4 To enhance the skill of the students for understanding of issues related

to faith and religious life.

Detail of Courses:

Introduction to Quranic Studies

1. Basic Concepts of Quran
2. History of Quran
3. Uloom-ul-Quran

Study of Selected Text of Holly Quran

1. Verses of Surah Al-Baqara Related to Faith (Verse No-284-286)
2. Verses of Surah Al-Hujrat Related to Adab Al-Nabi (Verse No-1-18)
3. Verses of Surah Al-Mumanoon Related to Characteristics of faithful (Verse No-1-11)
4. Verses of Surah al-Furqan Related to Social Ethics (Verse No.63-77)
5. Verses of Surah Al-Inam Related to Ihkam (Verse No-152-154)

Study of Selected Text of Holly Quran

1. Verses of Surah Al-Ihzab Related to Adab al-Nabi (Verse No.6, 21, 40, 56, 57, 58.)
2. Verses of Surah Al-Hashar (18,19,20) Related to thinking, Day of Judgment
3. Verses of Surah Al-Saf Related to Tafakar, Tadabar (Verse No-1,14)

Seerat of Holy Prophet (S.A.W) I

1. Life of Muhammad Bin Abdullah ( Before Prophet Hood)
2. Life of Holy Prophet (S.A.W) in Makkah
3. Important Lessons Derived from the life of Holy Prophet in Makkah

Seerat of Holy Prophet (S.A.W) II

1. Life of Holy Prophet (S.A.W) in Madina
2. Important Events of Life Holy Prophet in Madina
3. Important Lessons Derived from the life of Holy Prophet in Madina

Introduction to Sunnah

1. Basic Concepts of Hadith
2. History of Hadith