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Diabetes Meds & Insurance: ADA Recs & Coverage by BCBSMA, HPHC, Tufts, TMP, MassHealth, Study notes of Pharmacy

An overview of the American Diabetes Association (ADA) recommendations for treating type 2 diabetes (T2DM) in 2020, focusing on metformin and various classes of medications. The document also includes a tier coverage chart for BCBSMA, HPHC, Tufts, TMP, and MassHealth, detailing the A1C reduction and insurance coverage for each medication.

Typology: Study notes

2021/2022

Uploaded on 09/12/2022

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DIABETES RECOMMENDATIONS AND
TIER COVERAGE CHART
1 of 6 4/2020
The American Diabetes Association guidelines for 2020, recommend metformin as the preferred initial treatment for type 2 diabetes (T2DM) along with weight
management and physical activity. In patients who have established ASVD or at high risk, CKD, or HF, a SGLT2i or GLP-1 receptor with proven efficacy is recommended
independent of A1C.
ASCVD dominates:
o GLP-1RA with proven CVD benefit (dulaglutide, liraglutide, injectable semaglutide) OR
o SGLT2i with proven CVD benefit (canagliflozin, empagliflozin) if adequate eGFR
HF or CKD dominates:
o SGLT2i with evidence of reducing HF and/or CKD progression (empagliflozin, canagliflozin, dapagliflozin) if adequate eGFR OR
o If SGLT2i intolerant/contraindicated or eGFR is inadequate, then GLP-1RA with proven CVD benefit
In individuals without established cardiovascular disease, pharmacological treatment should be patient-centered taking into account side-effects, cost, impact on
weight, risk of hypoglycemia, and other patient preferences. For more detailed information regarding ADA recommendations for pharmacological agents to treat T2DM
click here.
The following chart is a list of oral and injectable diabetes medications listed by class with their respective A1C reduction and insurance coverage and/or coverage
requirements for BCBS, HPHC, Tufts, TMP, and MassHealth.
Medications
BCBSMA
HPHC
Tufts
Tufts Medicare
Preferred
MassHealth
Biguanides
A1C reduction: 1-1.5%
metformin
Tier 1;2
Tier 1
Tier 1
Covered
Glucoghage (metformin)
NC
NC
NC;Tier 3
NC
PA
metformin ER
Tier 1;2
Tier 1;2
Tier 1
Tier 1
Covered
Gluophage XR (metformin extended release)
NC
NC
NC;Tier 3
NC
PA
metformin solution
-
Tier 1;2
-
-
PA
Riomet solution
Tier 2;3;4
Tier 3;4
Tier 3; (-)
Tier 3
PA > 13 years
(Brand preferred)
Riomet ER solution
-
Tier 3;4
-
NC
-
pf3
pf4
pf5

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TIER COVERAGE CHART

The American Diabetes Association guidelines for 2020, recommend metformin as the preferred initial treatment for type 2 diabetes (T2DM) along with weight

management and physical activity. In patients who have established ASVD or at high risk, CKD, or HF, a SGLT2i or GLP-1 receptor with proven efficacy is recommended

independent of A1C.

  • ASCVD dominates:

o GLP-1RA with proven CVD benefit (dulaglutide, liraglutide, injectable semaglutide) OR

o SGLT2i with proven CVD benefit (canagliflozin, empagliflozin) if adequate eGFR

  • HF or CKD dominates:

o SGLT2i with evidence of reducing HF and/or CKD progression (empagliflozin, canagliflozin, dapagliflozin) if adequate eGFR OR

o If SGLT2i intolerant/contraindicated or eGFR is inadequate, then GLP-1RA with proven CVD benefit

In individuals without established cardiovascular disease, pharmacological treatment should be patient-centered taking into account side-effects, cost, impact on

weight, risk of hypoglycemia, and other patient preferences. For more detailed information regarding ADA recommendations for pharmacological agents to treat T2DM

click here.

The following chart is a list of oral and injectable diabetes medications listed by class with their respective A1C reduction and insurance coverage and/or coverage

requirements for BCBS, HPHC, Tufts, TMP, and MassHealth.

Medications BCBSMA HPHC Tufts

Tufts Medicare

Preferred MassHealth

Biguanides

A1C reduction: 1-1.5%

metformin (^) Tier 1 Tier 1;2 Tier 1 Tier 1 Covered Glucoghage ( metformin) NC NC NC;Tier 3 NC PA metformin ER Tier 1;2 Tier 1;2 Tier 1 Tier 1 Covered Gluophage XR (metformin extended release) NC NC NC;Tier 3 NC PA metformin solution - Tier 1;2 - - PA Riomet solution Tier 2;3;4 Tier 3;4 Tier 3; (-) Tier 3 PA > 13 years (Brand preferred) Riomet ER solution - Tier 3;4 - NC -

TIER COVERAGE CHART

Medications BCBSMA HPHC Tufts

Tufts Medicare

Preferred MassHealth

metformin extended release (modified) NC NC

PA

(Tier 2;3 once approved)

NC PA

Glumetza (metformin, modified release) NC NC NC NC PA metformin extended release (osmotic) NC Premium Formulary : Tier 1; Value Formulary : Tier 1;2;3;4 (depends on strength)

PA

(Tier 3 once approved)

NC PA

Fortamet (metformin, osmotic release) NC NC NC NC PA

Sodium-glucose co-transporter 2 Inhibitors (SGLT2)

A1C reduction: 0.5-1%

Jardiance (empagliflozin) Tier 2;3 (ST) Tier 2;3 Tier 2 Tier 3 Covered Invokana (canagliflozin) Tier 2;3 (ST) Tier 2;3 NC NC Covered Farxiga (dapagliflozin) NC Tier 3;4 NC Tier 3 Covered Steglatro (ertugliflozin)* NC Tier 3;4 NC NC PA

Glucagon-like Peptide-1 (GLP-1) Receptor Agonists**

A1C reduction: 1-1.5%

Trulicity (dulaglutide) Tier 2;3 (ST) Tier 2;3 (ST) Tier 2 Tier 3 (^) PA Ozempic (semaglutide) NC Tier 2;3 (ST) Tier 2 Tier 3 PA Rybelsus (oral semaglutide) NC NC NC NC - Victoza (liraglutide) NC Tier 2;3 (ST) Tier 2 Tier 3 PA Bydureon (exenatide extended release) Tier 2;3 (ST) Tier 2;3 (ST) NC Tier 3 Covered Bydureon BCise Tier 2;3 (ST) Tier 2;3 (ST) NC Tier 3 PA Byetta (exenatide) Tier 2;3 (ST) Tier 2;3 (ST) NC Tier 4 Covered (Brand preferred) Adlyxin (lixisenatide) NC Premium Formulary : Tier 3;4 (ST) Value Formulary : NC

NC NC PA

TIER COVERAGE CHART

Medications BCBSMA HPHC Tufts

Tufts Medicare

Preferred MassHealth

glyburide Tier 1;2 Tier 1;2 Tier 1

PA

(Tier 2 once approved) Covered glyburide micronized tablets Tier 1;2 Tier 1;2 Tier 1

PA

(Tier 1 once approved) Covered Glynase Prestab (glyburide micronized tablets) Tier 2;3;4 NC Tier 3 NC PA

Meglitinides

A1C reduction: 0.5-1%

repaglinide Tier 1;2 Tier 1;2 Tier 1 Tier 1 Covered nateglinide Tier 1;2 Tier 1;2 Tier 1 Tier 3 Covered Starlix (nateglinide) Tier 2;3;4 NC Tier 3 NC PA

Thiazolidinediones

A1C reduction: 1-1.5%

pioglitazone Tier 1;2 (ST) Tier 1;2 Tier 1 Tier 1 Covered Actos (pioglitazone) Tier 2;3;4 (ST) NC Tier 3 NC PA Avandia (rosiglitazone) Tier 2;3;4; (ST) Tier 3;4 NC NC PA

Alpha-Glucosidase Inhibitors

A1C reduction: 0.5-1%

acarbose Tier 1;2 Tier 1;2 Tier 1 Tier 1 Covered Precose (acarbose) Tier 2;3 NC Tier 3 NC PA miglitol Tier 1;2 Tier 1;2 Tier 2 Tier 3 Covered Glyset (miglitol) Tier 2;3;4 NC Tier 3 NC PA

Miscellaneous

A1C reduction: 0.5%

Cycloset (bromocriptine) Tier 2;3;4 Tier 2;3 Tier 2 Tier 3 PA

TIER COVERAGE CHART

Medications BCBSMA HPHC Tufts

Tufts Medicare

Preferred MassHealth

colesevelam Tier 1;2 Tier 2;3 Tier 2 Tier 3 PA Welchol (colesevelam) NC NC NC NC Covered (Brand preferred) SymlinPen (pramlintide) Tier 2;3 Tier 2;3 Tier 3 Tier 3 PA

Combination Products

metformin/glipizide Tier 1;2 Tier 1;2 Tier 1 Tier 1 Covered metformin/glyburide Tier 1;2 Tier 1;2 Tier 1 PA (Tier 2 once approved) Covered metformin/repaglinide Tier 1;2 NC Tier 1 NC PA pioglitazone/metformin Tier 1;2 (ST) Tier 1;2 Tier 1 Tier 3 PA Actoplus Met (pioglitazone/metformin) Tier 2;3;4 (ST) NC Tier 3 NC PA Actoplus Met XR (pioglitazone/metformin extended release) Tier 2;3;4 (ST) NC Tier 3 NC PA alogliptin/metformin NC NC Tier 1 NC PA Kazano (alogliptin/metformin) NC NC NC NC PA Janumet (sitagliptin/metformin) Tier 2;3 (ST) Tier 2;3 Tier 2 Tier 3 Covered Janumet XR (sitagliptin/metformin extended release) Tier 2;3 (ST) Tier 2;3 Tier 2 Tier 3 Covered Jentadueto (linagliptin/metformin) NC Tier 2;3 NC Tier 3 Covered Jentadueto XR (linagliptin/metformin extended release) NC Tier 2;3 NC Tier 3 PA Kombiglyze XR (saxagliptin/metformin extended release) Tier 2;3 (ST) NC NC NC Covered Invokamet (canagliflozin/metformin) Tier 2;3 (ST) Tier 2;3 NC NC Covered Invokamet XR (canagliflozin/metformin extended release) Tier 2;3 (ST) Tier 2;3 NC NC PA Xigduo XR (dapagliflozin/metformin extended release) NC Tier 3;4 NC Tier 3 Covered Synjardy (empagliflozin/metformin) Tier 2;3 (ST) Tier 2;3 Tier 2 Tier 3 PA Synjardy XR (empagliflozin/metformin extended release) Tier 2;3 (ST) Tier 2;3 Tier 2 Tier 3 PA