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DOACS summary dosing and crcl cut off
Typology: Summaries
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2.5 mg twice daily*
150 mg BID AFTER 5-10 days parenteral anticoagulation (i.e. heparin or LMWH) 10 mg BID for 7 days à 5 mg BID 15 mg BID for 21 days à 20 mg daily with food 60 mg daily AFTER 5-10 days parenteral anticoagulation (i.e. heparin or LMWH)
150 mg BID (if CrCl >30 ml/min) *After previous treatment 2.5 mg BID *After >6 months 10 mg daily (with/without food) *After >6 months Not in labeling
CrCl <30: AVOID No dose adjustment (CrCl <25 not studied) CrCl <30: AVOID CrCl 15 – 50: 30mg CrCl <15: AVOID
