DNA Mutation Practice Worksheet, Exercises of Genetics

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mo DNA Mutations Practice Worksheet DIRECTIONS: Transcribe and translate the original DNA sequence. Then, do the same for each mutated DNA sequence. Then, determine the consequence, if any, for each mutation, by circling your choice for each question. You will need a Genetic Code Chart. Original DNA sequence: MRNA transcript: TAC ACC TTG GCG ACG ACT L Ueird amino cast — teas Ig ‘A = fa a 7 Mutated DNA sequence #1: TAC ATC TTG GCG ACG ACT MRNA transcript: (Circle any changes) amino acids: Ave | fe DAC CH UGE tL wil Type of mutation {Circle one.} Point 3 Frameshift 3 (Substitution “> Deletion Insertion or How did the mutation affect the amino acid sequence (protein)? (Circle one.) No change Prémiature ¥ stop signal hs - All the amino acids changed after the point of mutation 1 amino acid added/ deleted 1 amino acid changed [No stop | “signal Mutated DNA sequence #2: TAC GAC CTT GGC GAC GAC T MRNA transcript: (Circle any changes) Av te Ke GAK 5 CUES Ut & amino acids: - * - Type of mutation (Circle one.) * Point > ns ~ ‘Tew ~ (I Vv bew > L td Frameshift 77> © /. tisertion ~ or 2 Deletion Substitution How did the mutation affect ee the amino acid sequence (protein)? (Circle one.) No change 1 amino acid changed Premature” stop signal, I. No stop| signal / 1 amino acid added/ deleted All the amino acids ‘ changed after the hk Point of mutation