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This study guide covers key concepts in genetics and molecular biology, including inheritance patterns, gene linkage, recombination frequencies, dna structure and replication, and the central dogma of molecular biology. It provides a comprehensive overview of these topics, with multiple-choice questions and answers to test understanding. The guide is particularly useful for students preparing for ebio 1210 exam 4.
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Combinations of alleles that are non-parental are called.... - ansRecombinant Genes located on the same chromosome that tend to be inherited together are called.... - ansLinked genes What is the advantage of doing a test cross vs. an F1xF1 cross? - ansWe know the patterns of heredity We can isolate what is actually going on What is the mechanism for recombining alleles? - ansCrossing over in Meiosis I Genetic map of a chromosome based on recombination frequencies - ansLinkage Map One map unit = ____% recombination frequency - ans1% Independent assortment does NOT (always) apply to genes on the same chromosome. Why not? A. Allele combinations on a chromosome can never be broken up B. A combination of alleles on one chromosome is less likely to be broken up than a combination of alleles from multiple chromosomes C. Non-homologous chromosomes pair up during meiosis D. Meiosis makes it impossible to create non-parental combinations of alleles in gametes. - ansB. A combination of alleles on one chromosome is less likely to be broken up than a combination of alleles from multiple chromosomes Why would some genes be inherited neither completely together nor completely independently? - ansRecombination of linked genes Suppose we are investigating two characters (e.g.,body color and wing type) in a study of heredity. If the ratio in the offspring of parental types : recombinant types is intermediate between the predictions of dependent assortment and independent assortment, then we should conclude that: A. meiosis has been disrupted in the parents used to produce the observed offspring B. the parents used to produce the offspring have cancer C. Mendel's law of segregation has been violated D. This outcome should never happen because Mendel's law of independent assortment holds for any two genes we consider E. The genes responsible for the phenotypes we are observing are "linked," i.e., located near each other on the same chromosome - ansE. The genes responsible for the phenotypes we are observing are "linked," i.e., located near each other on the same chromosome How can information about recombination frequencies be used to make a genetic map? - ansAssume that genes that are farther apart will show higher recombination frequencies A genetic map of chromosomes based on recombination frequencies - ansLinkage map What is the formula for recombination frequency? - ans(# of recombinants/ total # of Offspring) x 100 In experiments with two fruit fly characters like those we just learned about, suppose that the raJo of the two parental types and the two recombinant types was 1:1:1:1. What would the recombination frequency be? A. 25% B. 50%
E. not enough information given - ansB. 50% What can explain a recombination frequency of 50%? - ansGenes that are far apart on the same chromosome behave as if they are unlinked Can multiple crossover events PER chromosome occur? - ansYes. And these an affect observed recombination frequencies. What is a nucleic acid? - ansA polymer made of nucleotide monomers. What is the 5' and 3' end of DNA? - ans5' End- Sugar phosphate backbone 3' End- Sugar (deoxyribose) A nucleotide consists of: - ans1. A nitrogenous base
A. Open double helix---> Build RNA primer ---> Add DNA to 3' end of RNA primer ---> Replace RNA primers with DNA B. Open double helix---> Build DNA primer---> Add DNA to 5' end of DNA primer C. Open double helix---> Build RNA primer---> Add RNA to 3' end of RNA primer - ansA.
A. The genetic code for all of the alleles from one chromosome B. The genetic code for one allele from one chromosome C. The genetic code for both alleles you have of that gene - ansB. The genetic code for one allele from one chromosome Which cells in the albino deer have the albino mutation? A. Only one cell B. All of its cells C. Only its gametes D. Only its cells that grow hair E. Half of its cells - ansB. All All of the cells in your body have basically the same genome Successful transcription requires 3 basic processes: - ans1. Initiation
**Cannot be C because viruses don't have cells How does a virus do its business? - ans1. Virus enters the cell
B. No effect C. Cause a different amino acid to appear in the protein at the location corresponding to this codon D. Cause a longer version of the protein to be produced - ansA. Shortened version How do DNA mutations alter proteins? - ans1. Substitution: Switching one nucleotide for another
Cells in two regions secrete proteins (inducers) providing positional information: - ans1. ZPA (anterior-posterior)