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Population Evolution: Mutation, Drift, Selection, and Gene Flow, Study notes of Biology

An overview of evolution as the heritable change in a line of descent, focusing on microevolution and the factors that contribute to it: mutation, genetic drift, natural selection, and gene flow. It clarifies misconceptions about natural selection and explains how these processes shape populations, with examples of their impact on gene frequencies.

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Pre 2010

Uploaded on 08/16/2009

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Sylfae Bio 100
Chap 12
Evolution – heritable change in a line of descent; occurs by mutation, natural selection, genetic drift and
gene flow.
Microevolution - A change in gene frequency in a population.
Individuals do not evolve , populations do. A population is defined as any group that can
successfully interbreed.
Individuals in a population share a gene pool. All of the genes in the entire population constitute the gene
pool.
Mutation – heritable change in the sequence of DNA; the only source of new alleles
Lethal
Neutral
Beneficial – bestow survival advantages
Genetic drift – Change in allele frequencies in a population over time due to chance alone. Effects are
most pronounced in small populations.
In each generation, some individuals may, just by chance, leave behind a few more
descendents (and genes, of course!) than other individuals. The genes of the next generation will be the
genes of the "lucky" individuals, not necessarily the healthier or "better" individuals. That, in a nutshell, is
genetic drift. It happens to ALL populations — there's no avoiding the vagaries of chance.
Natural selection – differences in survival and reproduction among individuals of a population
Misconceptions about natural selection
Because natural selection can produce amazing adaptations, it's tempting to think of it as an all-powerful
force, urging organisms on, constantly pushing them in the direction of progress — but this is not what
natural selection is like at all.
First, natural selection is not all-powerful; it does not produce perfection. If your genes are "good enough,"
you'll get some offspring into the next generation — you don't have to be perfect. This should be pretty
clear just by looking at the populations around us: people may have genes for genetic diseases, plants
may not have the genes to survive a drought, a predator may not be quite fast enough to catch her prey
every time she is hungry. No population or organism is perfectly adapted.
Second, it's more accurate to think of natural selection as a process rather than as a guiding hand. Natural
selection is the simple result of variation, differential reproduction, and heredity — it is mindless and
mechanistic. It has no goals; it's not striving to produce "progress" or a balanced ecosystem.
This is why "need," "try," and "want" are not very accurate words when it comes to explaining evolution.
The population or individual does not "want" or "try" to evolve, and natural selection cannot try to supply
what an organism "needs." Natural selection just selects among whatever variations exist in the
population. The result is evolution. At the opposite end scale, natural selection is sometimes interpreted as
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Sylfae Bio 100

Chap 12

Evolution – heritable change in a line of descent; occurs by mutation, natural selection, genetic drift and gene flow. Microevolution - A change in gene frequency in a population.  Individuals do not evolve, populations do. A population is defined as any group that can successfully interbreed. Individuals in a population share a gene pool. All of the genes in the entire population constitute the gene pool. Mutation – heritable change in the sequence of DNA; the only source of new alleles Lethal Neutral Beneficial – bestow survival advantages Genetic drift – Change in allele frequencies in a population over time due to chance alone. Effects are most pronounced in small populations. In each generation, some individuals may, just by chance, leave behind a few more descendents (and genes, of course!) than other individuals. The genes of the next generation will be the genes of the "lucky" individuals, not necessarily the healthier or "better" individuals. That, in a nutshell, is genetic drift. It happens to ALL populations — there's no avoiding the vagaries of chance. Natural selection – differences in survival and reproduction among individuals of a population Misconceptions about natural selection Because natural selection can produce amazing adaptations, it's tempting to think of it as an all-powerful force, urging organisms on, constantly pushing them in the direction of progress — but this is not what natural selection is like at all. First, natural selection is not all-powerful; it does not produce perfection. If your genes are "good enough," you'll get some offspring into the next generation — you don't have to be perfect. This should be pretty clear just by looking at the populations around us: people may have genes for genetic diseases, plants may not have the genes to survive a drought, a predator may not be quite fast enough to catch her prey every time she is hungry. No population or organism is perfectly adapted. Second, it's more accurate to think of natural selection as a process rather than as a guiding hand. Natural selection is the simple result of variation, differential reproduction, and heredity — it is mindless and mechanistic. It has no goals; it's not striving to produce "progress" or a balanced ecosystem. This is why "need," "try," and "want" are not very accurate words when it comes to explaining evolution. The population or individual does not "want" or "try" to evolve, and natural selection cannot try to supply what an organism "needs." Natural selection just selects among whatever variations exist in the population. The result is evolution. At the opposite end scale, natural selection is sometimes interpreted as

a random process. This is also a misconception. The genetic variation that occurs in a population because of mutation is random-but selection acts on that variation in a very non-random way: genetic variants that aid survival and reproduction are much more likely to become common than variants that don't. Natural selection is NOT random. Gene flow (migration) – Alleles enter and leave a population when individuals move in (immigration), or out (emigration). Counters mutation, natural selection and genetic drift by keeping separated populations genetically similar. WHEN IS A POPULATION NOT EVOLVING? Five conditions are necessary for a stable population

  1. No mutations are occurring
  2. The population is very, very large.
  3. The population is isolated from other populations of the same species.
  4. All members survive, mate and reproduce (that is, there is not selection occurring)
  5. Mating is random (no inbreeding).