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Exercise Work Sheets, Assignments of Medicine

Powerpoint and explains the disease process

Typology: Assignments

2022/2023

Uploaded on 11/02/2024

sherry-sowders-welch
sherry-sowders-welch 🇺🇸

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Hepatitis Comparison Chart KEY
Causative
Agent
HAV HBV HCV HDV HEV
Common
Name
“Infectious” “Serum” “Post-
Transfusion”
“Delta” “Enteric”
Transmissio
n Route
Fecal-Oral
(Enteral)
Travelers to
Foreign
Countries
Parenteral
Sexual
Perinatal
Parenteral
Sexual
Parenteral
Sexual
Perinatal
Can only be
present w/HBV
Fecal-Oral
(Enteral)
Age Most
Affected
Children Any Adults
1945-1965
birth yrs. have
higher
incidence
Any Young Adults
Onset Abrupt Insidious Abrupt
However pt’s
can be
asymptomatic
for 15-20 yrs.
before s/s
Abrupt Abrupt
Incubation
Period
15-50
days
45-160
days
14-180
days
15-64
days
15-50
days
Carrier State N/A Yes Yes N/A N/A
Severity Mild Can be
Severe, especially
in kids <5yrs
Typically sub-
clinical
Infection with HBV
often severe
Mild for most
However
Severe for
Pregnant pt’s
Disease
Progression
50-70% show
symptoms
Abrupt onset
w/flu-like
symptoms
Self-limiting
Different
depending on age
and comorbidities
Typically
asymptomatic
Chronic s/s’s
include liver
cirrhosis and
CA
Different
depending on
age group
Can range from
asymptomatic
carrier state to
50-70% show
s/s’s
Pregnant Pt’s:
Severe S/S’s,
including
miscarriage
pf2

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Hepatitis Comparison Chart KEY

Causative Agent

HAV HBV HCV HDV HEV

Common Name “Infectious” “Serum” “Post- Transfusion” “Delta” “Enteric” Transmissio n Route  Fecal-Oral (Enteral)  Travelers to Foreign Countries  Parenteral  Sexual  Perinatal  Parenteral  Sexual  Parenteral  Sexual  Perinatal  Can only be present w/HBV  Fecal-Oral (Enteral) Age Most Affected Children Any  Adults  1945- birth yrs. have higher incidence Any Young Adults Onset Abrupt Insidious  Abrupt  However pt’s can be asymptomatic for 15-20 yrs. before s/s Abrupt Abrupt Incubation Period

days

days

days

days

days Carrier State N/A Yes Yes N/A N/A Severity Mild Can be Severe, especially in kids <5yrs Typically sub- clinical Infection with HBV often severe Mild for most However  Severe for Pregnant pt’s Disease Progression  50-70% show symptoms  Abrupt onset w/flu-like symptoms  Self-limiting Different depending on age and comorbidities  Typically asymptomatic  Chronic s/s’s include liver cirrhosis and CA  Different depending on age group  Can range from asymptomatic carrier state to  50-70% show s/s’s  Pregnant Pt’s: Severe S/S’s, including miscarriage

Hepatitis Comparison Chart KEY

acute liver failure Chronic ?? No Yes (up to 10%, w/kids having more chronicity) Yes (in 80%) Yes No Clinical Outcomes w/Chronic Inf. N/A Cirrhosis or Hepatocellular Carcinoma Cirrhosis or Hepatocellular Carcinoma Co-Infection with HBV

N/A

Prevention  IgG  Pre & Post Exposure Vaccine  Once you have HAV you are immune  HBIG for Post Exposure  Hep B Vaccine  Blood donor screening since 1992  HBV Vaccine  Ensure safe drinking water Cure?  No  TX symptoms  No  TX w/Interferon with varying success rates  No  TX w/Interferon with varying success rates  No  TX with Interferon for 12 months w/low success rates  No  TX symptoms Prognosis Excellent Worse with age & co-morbidities Moderate, depends on what damage has occurred Acute = Good Chronic = Poor Good