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Fibroid uterus summary, Summaries of Gynecology

Summary of the topic fibroid uterus

Typology: Summaries

2024/2025

Uploaded on 02/28/2025

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Fibroid Uterus: Key Learnings for MBBS Gynaecology Exam
Uterine fibroids, or leiomyomas, are benign smooth muscle tumors of the uterus. They are the most
common pelvic
tumors in women, particularly during the reproductive years. Understanding their characteristics,
clinical
implications, and management is crucial for gynecological practice.
Key Points:
1. Epidemiology:
- Fibroids are prevalent, with studies indicating that by age 50, approximately 50% of women have
them.
2. Etiology and Risk Factors:
- The exact cause is unknown, but factors include:
- Genetics: Family history increases risk.
- Hormones: Estrogen and progesterone promote fibroid growth.
- Lifestyle: Obesity and a diet high in red meat are associated with higher risk.
3. Classification:
- Based on location:
- Intramural: Within the uterine wall; most common.
- Subserosal: On the outer surface of the uterus.
- Submucosal: Beneath the uterine lining; often linked to heavy bleeding.
- Cervical: Located in the cervix; rare.
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Fibroid Uterus: Key Learnings for MBBS Gynaecology Exam

Uterine fibroids, or leiomyomas, are benign smooth muscle tumors of the uterus. They are the most common pelvic tumors in women, particularly during the reproductive years. Understanding their characteristics, clinical implications, and management is crucial for gynecological practice.

Key Points:

  1. Epidemiology:
    • Fibroids are prevalent, with studies indicating that by age 50, approximately 50% of women have them.
  2. Etiology and Risk Factors:
    • The exact cause is unknown, but factors include:
      • Genetics: Family history increases risk.
      • Hormones: Estrogen and progesterone promote fibroid growth.
      • Lifestyle: Obesity and a diet high in red meat are associated with higher risk.
  3. Classification:
    • Based on location:
      • Intramural: Within the uterine wall; most common.
      • Subserosal: On the outer surface of the uterus.
      • Submucosal: Beneath the uterine lining; often linked to heavy bleeding.
      • Cervical: Located in the cervix; rare.
  1. Clinical Features:
    • Many women are asymptomatic. When symptoms occur, they may include:
      • Menstrual Changes: Heavy or prolonged periods.
      • Pelvic Pressure: Sensation of fullness or pressure.
      • Reproductive Issues: Infertility or recurrent miscarriages.
  2. Diagnosis:
    • Pelvic Examination: May reveal an enlarged, irregular uterus.
    • Imaging: Ultrasound is the primary tool; MRI provides detailed information when needed.
  3. Management:
    • Conservative: Observation for asymptomatic cases.
      • Medical Therapy: Options include NSAIDs for pain, hormonal treatments, and GnRH agonists to reduce size.
    • Surgical: Myomectomy for those desiring fertility preservation; hysterectomy is definitive.
      • Minimally Invasive Procedures: Uterine artery embolization and MRI-guided focused ultrasound are alternatives.
  4. Complications:
    • Potential issues include severe anemia from heavy bleeding, urinary problems due to pressure effects, and rare malignant transformation into leiomyosarcoma.

For a comprehensive understanding, refer to the "DC Dutta's Textbook of Gynecology," which provides detailed insights into the pathophysiology, diagnosis, and management of uterine fibroids.