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Final Assessment for MT ASCP/AMT
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In absorption spectrophotometry: A) Absorbance is directly proportional to transmittance B) Percent transmittance is directly proportional to concentration C) Percent transmittance is directly proportional to the light path length D) Absorbance is directly proportional to concentration ✔✔Absorbance is directly proportional
to concentration
Which formula correctly described the relationship between absorbance and %T? A) A=2-log%T B) A=2+log%T C) A= -log%T - 2 D) A=1+log%T ✔✔A=2-log%T
Which element is reduced at the cathode of a Clark polarographic electrode? A) Silver B) Oxygen C) Chloride
D) Potassium ✔✔Oxygen
Which of the following best represents the reference (normal) range for arterial pH? A) 7.35-7. B) 7.42-7. C) 7.28-7.
D) 6.85-7.56 ✔✔7.35-7.
What is the normal ration of bicarbonate to dissolved carbon dioxide in arterial blood? A) 1: B) 10: C) 20: D) 30:1 ✔✔20:
A patient's blood gas results are as follows: pH = 7.26; dco2=2.0mmol/L; HCO3-=29mmol/L. These results would be classified as: A) Metabolic acidosis B) Metabolic alkalosis C) Respiratory acidosis D) Respiratory alkalosis ✔✔respiratory acidosis
A) Addison's disease B) Hemolytic anemia C) Digoxin intoxication
D) Alkalosis ✔✔Alkalosis
Which of the following condition is associated with hypernatremia? A) Diabetes insipidus B) Hypoaldosteronism C) Burns
D) Diarrhea ✔✔Diabetes insipidus
Which of the following values is the threshold critical value for low plasma potassium? A) 1.5mmol/L B) 2.0mmol/L C) 2.5mmol/L
D) 3.5mmol/L ✔✔2.5 mmol/L
Which electrolyte level best correlates with plasma osmolality? A) Sodium B) Chloride
C) Bicarbonate D) Calcium
: ✔✔Sodium
Which of the following is characteristic of type 1 diabetes mellitus? A) Requires an oral glucose tolerance test for diagnosis B) Is the most common form of diabetes mellitus C) Usually occurs after age 40
D) Requires insulin replacement to prevent ketosis ✔✔Requires insulin replacement to prevent
ketosis
Which of the following is the reference method for measuring serum glucose? A) Somogyi-Nelson B) Hexokinase C) Glucose oxidase
D) Glucose dehydrogenase ✔✔Hexokinase
Creatinine is formed from the: A) Oxidation of creatine B) Oxidation of protein
Which apoprotein is inversely related to risk for coronary heart disease? A) Apoprotein A-I B) Apoprotein B C) Apoprotein C-II
D) Apoprotein E-IV ✔✔Apoprotein A-I
Which condition produces the highest elevation of serum lactate dehydrogenase? A) Pernicious anemia B) Myocardial infarction C) Acute hepatitis
D) Muscular dystrophy ✔✔Pernicious anemia
A patient has a plasma myoglobin level of 10μg/L at admission. Three hours later the myoglobin is 14μ/L and the Troponin I is 0.04μg/L (reference range 0-0.04μg/L). These results are consistent with which condition? A) Skeletal muscle injury B) Acute MI C) Unstable angina
D) No evidence of myocardial or skeletal muscle injury ✔✔No evidence of myocardial or
skeletal muscle
Select the most sensitive marker for alcoholic liver disease A) GLD B) ALT C) AST
D) GGT ✔✔GGT
Hyperparathyroidism is most consistently associated with: A) Hypocalcemia B) Hypocalcuria C) Hypophosphatemia
D) Metabolic alkalosis ✔✔Hypophosphatemia
Which of the following diseases is characterized by primary hyperaldosteronism caused by adrenal adenoma, carcinoma, or hyperplasia? A) Cushing's disease B) Addison's disease C) Conn's disease
Which two liver enzymes are seen elevated in hepatobiliary disease? A) AST and ALT B) ALP and ALT C) ALP and GGT
D) AST and GGT ✔✔ALP and GGT
Beriberi is associated with deficiency of: A) Vitamin A B) Vitamin C C) Niacin
D) Thiamine ✔✔Thiamine
Zollinger-Ellison syndrome is characterized by a marked elevation of: A) Gastrin B) Cholecystokinin C) Pepsin
D) Glucagon ✔✔Gastrin
Scurvy is associated with deficiency of:
A) A
B) C
C) Niacin
D) Thiamine ✔✔C
This trace element plays a key role in protein and nucleic acid synthesis: A) Manganese B) Selenium C) Zinc
D) Copper ✔✔Zinc
In quality control, ±2 standard deviations from the mean include what percent of the sample population? A) 50 B) 68 C) 95
D) 99.7 ✔✔ 95
What is the metabolite of ethanol? A) Benzoylecgonine B) 6-acetylmorphine C) Acetaldehyde
D) Carboxylic acid ✔✔Acetaldehyde
What is the gold standard methodology for Toxicology testing? A) Immunoassay B) Electrophoresis C) Liquid Chromatography
D) Mass Spectrometry ✔✔Mass Spectrometry
Calculate the coefficient of variation for a set of data where the mean = 89 mg/dL and 2 standard deviations is A) 7.7% B) 7.9% C) 15.7%
D) 15.8% ✔✔7.9%
In the condition Kernicterus, the abnormal accumulation of bilirubin occurs in what tissue? A) Brain B) Liver C) Kidney
D) Blood ✔✔Brain
Which of the following is the major mineralocorticoid? A) Aldosterone B) Cortisol C) Corticosterone
D) Testosterone ✔✔Aldosterone
Select the main estrogen produced by the ovaries and used to evaluate ovarian function. A) Estriol B) Estradiol C) Epiestriol
D) Hydroxyestrone ✔✔Estradiol
Regan isoenzyme has the same properties as alkaline phosphatase that originates in the: A) Skeleton
D) Progesterone ✔✔Progesterone
Which of the formulas is correct for creatinine clearance? A) U/P x V x 1.73/A B) P/V x U x A/1. C) P/V x U x 1.73/A
D) U/V x P x 1.73/A ✔✔U/P x V x 1.73/A
Which hormone controls sodium reabsorption? A) Aldosterone B) Anti-Diuretic Hormone C) Renin
D) Angiotensin II ✔✔Aldosterone
The thyrotropin releasing hormone (TRH) stimulation test rules out the diagnosis of mild or subclinical hyperthyroidism if TRH infusion causes: A) Rise in plasma TSH B) No rise in plasma TSH C) Rise in plasma growth hormone D) No rise in plasma growth hormone ✔✔Rise in plasma TSH
What test is used along with the mean cell volume (MCV) to morphologically classify anemias? A) red blood count B) hemoglobin C) hematocrit
D) red cell distribution width (RDW) ✔✔red cell distribution width (RDW)
Transferrin receptors can be measured and are elevated when: A) erythropoietin increases B) transferrin increases C) iron stores are decreased
D) chronic disease is present ✔✔iron stores are decreased
Mature T cells with cerebriform, clefted nuclei found in the skin and peripheral blood describe: A) hairy cells B) prolymphocytes C) lymphoblasts
D) Sézary cells ✔✔Sezary cells
B) hexose monophosphate pathway C) adenosine triphosphate (ATP) generated from anaerobic glycolysis
D) adenosine diphosphate (ADP) generated from aerobic glycolysis ✔✔adenosine triphosphate
(ATP) generated from anaerobic glycolysis
What important function does 2,3-biphosphoglycerate (2,3-BPG) perform? A) maintains iron in the hemoglobin molecule in the ferrous state B) prevents oxidative injury to the red cell C) facilitates the delivery of oxygen to tissue
D) aids in the exchange of membrane lipids with lipids in plasma ✔✔facilitates the delivery of
oxygen to tissue
Which of the following is true of megakaryocytes as they mature? A) nucleus becomes polyploidy B) cytoplasmic basophilia becomes more pronounced C) size decreases
D) nucleoli become more prominent ✔✔nucleus becomes polyploidy
Lymphocytes become transformed when they are: A) being stimulated by an antigen
B) undergoing mitosis C) dying
D) moving to secondary lymphoid tissues ✔✔being stimulated by an antigen
What is the basic hemoglobin defect in the thalassemias? A) One of the globin chains has an amino acid substitution B) A structurally normal globin chain is absent or produced at lower levels C) Heme is produced at a lower concentration
D) Iron is not incorporated into the protoporphyrin ring to form heme ✔✔A structurally normal
globin chain is absent or produced at lower levels
Why are infants with beta-thalassemia major not ill until approximately 6 months of age? A) Infants are protected by their high concentration of fetal hemoglobin. B) Infants have less need for hemoglobin because of their small body size. C) Infants have less need for hemoglobin because of their smaller lung capacity. D) Infants have a high red count and thus higher hemoglobin from a higher than normal
concentration of erythropoietin. ✔✔Infants are protected by their high concentration of fetal
hemoglobin
A patient has 30% hemoglobin F. Which of the following can be eliminated?
