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Definitions and functions of various cellular structures, including actin microfilaments, microtubules, t and g forms, treadmilling, catastrophe, rescue, map motor proteins, phalloidin, cytochalasin, swinholide, taxol, colchicine, nocodazole, intermediate filaments, anchoring junctions, cadherins, desmosomes, occluding junctions, basal lamina, integrins, and specific integrin subtypes. The document also includes information on flow cytometry and cdc genes.
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determine cells shapeplus and minus enduses ATPcontacts between cells and matrixdynamic TERM 2
DEFINITION 2 determine positions of organelles and direct intracellular transportcomposed of alpha and beta tubulinplus and minus enduses GTPmoves chromosomes during mitosisdynamic TERM 3
DEFINITION 3 atp (actin) gtp (microtubules)rate of subunit addition is fast --
rapidly growing filamentpolymerization occurs on the plus sideif gtp alpha S is added: non hydrolyzable form of GTP --> stabilize TERM 4
DEFINITION 4 adp (actin) gdp (microtubules)rate of subunit addition is slow TERM 5
DEFINITION 5 when plus end is growing (right) and minus end shrinks (left)plus end balances the shrinking of minus endactin and microtubules
rapid shrinking (loss of GTP cap)dynamic instability TERM 7
DEFINITION 7 growth or regain of GTP cap TERM 8
DEFINITION 8 transport organelles along microtubuleskinesin: moves towards plus end, uses ATPdynein: moves towards minus end of microtubules TERM 9
DEFINITION 9 drug that binds and stabilizes actin filaments TERM 10
DEFINITION 10 drug that caps actin filament plus ends
important transmembrane proteins with cell to cell junctiondependent on Calcium2+ to create adhesion TERM 17
DEFINITION 17 similar to adheren junctions but link intermediate filamentsprovide mechanical strengthbetween cells using intermediate filaments and cadherins TERM 18
DEFINITION 18 aka tight junctionsjunctions between cells esp. gut epitheliumprevents passage of molecules to apical sides to basal side (almost impermeable to fluid and cells between cells)if lost: leads to inflammation TERM 19
DEFINITION 19 mediates cell to matrix attachmentsinfo. "stored" in structure: signals where they should be going/what they should be doing"detected" by nerve and muscles TERM 20
DEFINITION 20 principal transmembrane receptors for most extracellular matrix proteinscan be activated by the inside or outsidecomposed of alpha and beta subunits
binds fibronectinfound in all types TERM 22
DEFINITION 22 binds lamin: found in muscle cells TERM 23
DEFINITION 23 binds lamin: foundin hemidesmosomes TERM 24
DEFINITION 24 measures DNA content (doubles in S phase) used to determine length of each phaseFlow cytometry is a technique for counting and examining microscopic particles, such as cells and chromosomes, by suspending them in a stream of fluid and passing them by an electronic detection apparatus. TERM 25
DEFINITION 25 control cell cycle checkpoints, helps to control mitosis