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Fitzgerald Chapter 2 Quiz and answers verified to pass 2025
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Increase in serum albumin. - correct answer ✔Age-related changes in the elder include all of the following except: An increased risk of cardiovascular death with azithromycin is likely limited to high-risk patient populations. - correct answer ✔Which of the following statements is most accurate regarding the use of azithromycin and cardiovascular death? Bioavailability and half-life - correct answer ✔Of the following drug characteristics, which contributes significantly to the difference in the HMG- CoA reductase inhibitors (the statins) potencies? 8 - correct answer ✔A nursing mother is taking a medication with a 2-hour half-life and is concerned about her infant ingesting some of the drug through breastmilk. The NP knows that <10% of the original drug dose will remain in the body after how many hours following her dose? Determining the effect of a specific medication dose in treating a disease - correct answer ✔Which of the following would best describe a pharmacodynamic study? Vertigo. - correct answer ✔All of the following are potential signs of Torsades de Pointe except: Does the medication appear to have a clinical effect when subjected to a double-blind clinical trial? - correct answer ✔In the development, testing, and
approval of a new medication, which of the following best describes the question that is being asked in phase 3 testing? Phase 1 - correct answer ✔The safety and pharmacokinetics of a new drug are best determined in which phase of clinical trials? Stimulating the activity of a receptor site. - correct answer ✔Agonist drugs work primarily by: The oral dose of the medication needed is quite high compared to the injectable for due to issues with GI absorption. - correct answer ✔When counseling a 56-year-old woman with type 2 diabetes mellitus, the NP mentions which of the following regarding the use of semaglutide? Pharmacodynamics. - correct answer ✔A drug's mechanism of action is part of its: Moxifloxacin - correct answer ✔A 63-year-old man with a history of ventricular arrhythmia is diagnosed with community-acquired pneumonia. Which of the following oral medications should be avoided due to the risk of QT prolongation? Frovatriptan - correct answer ✔A 37-year-old woman with a history of migraines requests a migraine treatment. She describes that her migraines tend to develop slowly and will last several hours. The NP recommends which of the following triptans? Time to maximum drug level is observed. - correct answer ✔Tmax is best defined as:
Aside from close clinical monitoring and periodic checking of INR, the NP considers which of the following adjustments to therapy? 3A4 - correct answer ✔The most commonly utilized CYP 450 isoenzyme for drug metabolism or biotransformation is: Occupying a receptor site and inhibiting its endogenous activity. - correct answer ✔Drugs that are antagonists exhibit clinical action primarily by: Should be taken on an empty stomach. - correct answer ✔When counseling a 58-year-old woman on the use of levothyroxine, the NP advises that the medication: Maximum or peak concentration of a drug observed after its administration. - correct answer ✔Cmax is best described as: The clinical effect of the antimicrobial will be reduced via chelation if the two medications are taken together. - correct answer ✔In advising a 40-year-old woman who is taking ciprofloxacin with a calcium-containing antacid, which of the following statement is correct? pH <4 in aqueous medium - correct answer ✔Which of the following is not a requirement for a medication to be delivered transdermally? Pravastatin - correct answer ✔Which of the following statins would be preferred for a 67-year-old man with hypercholesterolemia and who likes to have a glass of grapefruit juice every morning?
St. John's wort will decrease the effectiveness of the antiviral. - correct answer ✔A 42-year-old man is taking indinavir for HIV infection. He mentions that he wishes to start taking St. John's wort to help with some depression he has been feeling lately. The NP advises: