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Essential information about albuterol sulfate, a sympathomimetic bronchodilator. Learn about its mechanism of action, indications, contraindications, adverse reactions, dosage for adults and children, routes of administration, onset, peak effects, and duration of action. Also, find notes on incompatibilities and special considerations.
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GD-028-PHS-EMS: Drug Profile for Albuterol Sulfate
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BRAND NAME: Proventil, Ventolin CLASS: sympathomimetic, bronchodilator
Mechanism of Action:
ß agonist (primarily ß 2 ); relaxes bronchial smooth muscle, resulting in bronchodilation; also relaxes vascular and uterine smooth muscle; decreases airway resistance
Indications and Field Use:
Treatment of bronchospasm
Contraindications:
Synergistic with other sympathomimetics Use caution in patients with diabetes, hyperthyroidism, and cerebrovascular disease
Adverse Reactions:
CV : Dysrhythmias, tachycardia (with excessive use), peripheral vasodilation Resp: Bronchospasm (rare paradoxical with excessive use) CNS: Tremors, nervousness GI: Nausea, vomiting Endocrine: Hyperglycemia
Incompatibilities/Drug Interactions:
Tricyclic antidepressants (TCA's) and monoamine oxidase (MAO) inhibitors Other sympathomimetics (relative)
Adult Dosage:
Give 2.5 mg of premixed solution for inhalation (0.083%) via SVN with a mouth piece, or in-line with a ventilatory device. Repeated according to medical control preference
Pediatric Dosage: (children <40 lbs)
For children < 40 lbs., administer half of 0.083% premixed solution; add 1-1.5 ml NS to make 2.5-3 cc inhalation treatment administered via SVN with a mouth piece, O 2 mask or in-line with a ventilatory device. May be repeated according to medical control preference
GD-028-PHS-EMS: Drug Profile for Albuterol Sulfate
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Routes of Administration:
Nebulized, mouth piece or in-line via mask Inhaler, patients own ET/NT in-line
Onset of Action:
5-15 minutes
Peak Effects:
30 minutes - 2 hours
Duration of Action:
3-4 hours
Dosage Forms/Packaging:
2.5 mg albuterol premixed in 3 ml normal saline (independent dose) sulfite-free
Arizona Drug Box Supply Range:
PARAMEDIC: 2 - 6 independent doses INTERMEDIATE: 2 - 6 independent doses
Special Notes:
Must be sulfite-free