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Drug Profile: Albuterol Sulfate - Mechanism, Indications, Dosage, and Adverse Reactions, Lecture notes of Medical statistics

Essential information about albuterol sulfate, a sympathomimetic bronchodilator. Learn about its mechanism of action, indications, contraindications, adverse reactions, dosage for adults and children, routes of administration, onset, peak effects, and duration of action. Also, find notes on incompatibilities and special considerations.

What you will learn

  • What are the adverse reactions associated with Albuterol Sulfate?
  • What is the mechanism of action of Albuterol Sulfate?
  • How should Albuterol Sulfate be administered to adults and children?
  • What are the contraindications for using Albuterol Sulfate?
  • What are the indications for using Albuterol Sulfate?

Typology: Lecture notes

2021/2022

Uploaded on 09/12/2022

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GD-028-PHS-EMS: Drug Profile for Albuterol Sulfate
Page 1 of 2 1/99
GENERIC NAME: ALBUTEROL SULFATE
112.03
BRAND NAME: Proventil, Ventolin
CLASS: sympathomimetic, bronchodilator
Mechanism of Action:
ß agonist (primarily ß2); relaxes bronchial smooth muscle, resulting in bronchodilation;
also relaxes vascular and uterine smooth muscle; decreases airway resistance
Indications and Field Use:
Treatment of bronchospasm
Contraindications:
Synergistic with other sympathomimetics
Use caution in patients with diabetes, hyperthyroidism, and cerebrovascular disease
Adverse Reactions:
CV: Dysrhythmias, tachycardia (with excessive use), peripheral vasodilation
Resp: Bronchospasm (rare paradoxical with excessive use)
CNS: Tremors, nervousness
GI: Nausea, vomiting
Endocrine: Hyperglycemia
NOTES ON ADMINISTRATION
Incompatibilities/Drug Interactions:
Tricyclic antidepressants (TCA's) and monoamine oxidase (MAO) inhibitors
Other sympathomimetics (relative)
Adult Dosage:
Give 2.5 mg of premixed solution for inhalation (0.083%) via SVN with a mouth piece,
or in-line with a ventilatory device. Repeated according to medical control preference
Pediatric Dosage: (children <40 lbs)
For children < 40 lbs., administer half of 0.083% premixed solution; add 1-1.5 ml NS to
make 2.5-3 cc inhalation treatment administered via SVN with a mouth piece, O2 mask or
in-line with a ventilatory device. May be repeated according to medical control
preference
pf2

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GD-028-PHS-EMS: Drug Profile for Albuterol Sulfate

Page 1 of 2 1/

GENERIC NAME: ALBUTEROL SULFATE

BRAND NAME: Proventil, Ventolin CLASS: sympathomimetic, bronchodilator

Mechanism of Action:

ß agonist (primarily ß 2 ); relaxes bronchial smooth muscle, resulting in bronchodilation; also relaxes vascular and uterine smooth muscle; decreases airway resistance

Indications and Field Use:

Treatment of bronchospasm

Contraindications:

Synergistic with other sympathomimetics Use caution in patients with diabetes, hyperthyroidism, and cerebrovascular disease

Adverse Reactions:

CV : Dysrhythmias, tachycardia (with excessive use), peripheral vasodilation Resp: Bronchospasm (rare paradoxical with excessive use) CNS: Tremors, nervousness GI: Nausea, vomiting Endocrine: Hyperglycemia

NOTES ON ADMINISTRATION

Incompatibilities/Drug Interactions:

Tricyclic antidepressants (TCA's) and monoamine oxidase (MAO) inhibitors Other sympathomimetics (relative)

Adult Dosage:

Give 2.5 mg of premixed solution for inhalation (0.083%) via SVN with a mouth piece, or in-line with a ventilatory device. Repeated according to medical control preference

Pediatric Dosage: (children <40 lbs)

For children < 40 lbs., administer half of 0.083% premixed solution; add 1-1.5 ml NS to make 2.5-3 cc inhalation treatment administered via SVN with a mouth piece, O 2 mask or in-line with a ventilatory device. May be repeated according to medical control preference

GD-028-PHS-EMS: Drug Profile for Albuterol Sulfate

Page 2 of 2 1/

Routes of Administration:

Nebulized, mouth piece or in-line via mask Inhaler, patients own ET/NT in-line

Onset of Action:

5-15 minutes

Peak Effects:

30 minutes - 2 hours

Duration of Action:

3-4 hours

Dosage Forms/Packaging:

2.5 mg albuterol premixed in 3 ml normal saline (independent dose) sulfite-free

Arizona Drug Box Supply Range:

PARAMEDIC: 2 - 6 independent doses INTERMEDIATE: 2 - 6 independent doses

Special Notes:

Must be sulfite-free