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Genetics Overview in Biotech, Study notes of Genetics

Overview of Genetics Overview in Biotech

Typology: Study notes

2019/2020

Uploaded on 03/07/2025

ankush-singla
ankush-singla 🇺🇸

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Genetics Overview
Genetics is the study of heredity and the variation of inherited
characteristics. It focuses on how traits are passed from
parents to offspring through genes. Here are some key
concepts:
1. DNA (Deoxyribonucleic Acid): DNA is the molecule that
carries genetic information in all living organisms. It is
structured as a double helix and consists of four bases:
A (Adenine), T (Thymine), C (Cytosine), G (Guanine).
The sequence of these bases forms the genetic code.
2. Genes: Genes are segments of DNA that contain the
instructions for building proteins, which perform various
functions in the body. Each gene has a specific location
on a chromosome. They determine physical traits (eye
color, height) and biological functions (immune
response, metabolism).
3. Chromosomes: DNA is packed into chromosomes,
which are found in the cell nucleus. Chromosomes are
long, thread-like structures made of DNA and proteins.
Humans have 46 chromosomes, arranged in 23 pairs.
4. Inheritance: Mendelian Genetics 🌱
oDiscovered by Gregor Mendel, who studied how
traits are inherited in pea plants.
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Genetics Overview Genetics is the study of heredity and the variation of inherited characteristics. It focuses on how traits are passed from parents to offspring through genes. Here are some key concepts:

1. DNA (Deoxyribonucleic Acid): DNA is the molecule that carries genetic information in all living organisms. It is structured as a double helix and consists of four bases: A (Adenine), T (Thymine), C (Cytosine), G (Guanine). The sequence of these bases forms the genetic code.

  1. Genes: Genes are segments of DNA that contain the instructions for building proteins, which perform various functions in the body. Each gene has a specific location on a chromosome. They determine physical traits (eye color, height) and biological functions (immune response, metabolism).
  2. Chromosomes: DNA is packed into chromosomes , which are found in the cell nucleus. Chromosomes are long, thread-like structures made of DNA and proteins. Humans have 46 chromosomes, arranged in 23 pairs. 4. Inheritance: Mendelian Genetics 🌱 o Discovered by Gregor Mendel , who studied how traits are inherited in pea plants.

o Key principles:  Dominant & Recessive Traits: Dominant traits (e.g., brown eyes) override recessive ones (e.g., blue eyes).  Law of Segregation: Each parent passes one allele per gene to offspring.  Law of Independent Assortment: Genes for different traits are inherited independently.

5. Types of Inheritance Patterns o Dominant-Recessive: One allele is dominant (e.g., Huntington’s disease). o Codominance: Both alleles are fully expressed (e.g., AB blood type). o Incomplete Dominance: A blend of traits (e.g., red + white flowers = pink). o Polygenic Inheritance: Traits controlled by multiple genes (e.g., height, skin color). o Sex-Linked Traits: Genes on X or Y chromosomes (e.g., color blindness). 6. Modern Genetics & Applications Genetic Engineering & CRISPR 🌱