Chapter 17:
Immunology I: Basic Principles of
Adaptive Immunity and
Immunization
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Immunology I - Microbiology and Immunology - Notes | BIOL 1463, Study notes of Biology
Immunology I Material Type: Notes; Professor: Pritchett; Class: Microbiology and ImmunologyHS; Subject: Biology; University: University of Arkansas-Fort Smith; Term: Fall 2010;
Typology: Study notes
2009/2010
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Chapter 17:
Immunology I: Basic Principles of
Adaptive Immunity and
Immunization
Immunity
- (^) Generalized protection
- (^) Provides Resistance (^) Susceptible vs. Resistant
- (^) Resistance can be either (^) non-specific or specific (^) Innate or Acquired (Adaptive)
- (^) Immunology—
- (^) Study of acquired specific immunity (resistance)
Adaptive Immunity
- (^) Naturally acquired active immunity
- (^) Resulting from infection
- (^) Naturally acquired passive immunity
- (^) Transplacental or via colostrum
- (^) Artificially acquired active immunity
- (^) Injection of Ag (vaccination)
- (^) Artificially acquired passive immunity
- (^) Injection of Ab
The surfaces of viruses and all cells are
complex structures…
- (^) The exact chemical composition and structure of these surface features is unique to each cell or virus.
- (^) It is genetically determined.
- (^) Remember that good antigens must be
sufficiently large and unique in structure..
- (^) Which type of organic molecule do you
think best fits these criteria?
- (^) Proteins, carbohydrates or lipids?
Haptens?
- (^) Small molecular weight structures that are
too small to initiate immune response on
their own
- (^) Can be conjugated with carrier molecules
Antibody
- (^) An antibody is a specialized protein that can
be produced in one type of immune
reaction.
- (^) These proteins are anti-antigenic.