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Interpretation and Revision of Diagnostic Test Performance, Slides of Public Health

Information on the interpretation of diagnostic data using conditional probabilities and calculating predictive values based on prevalence. It includes tables for calculating true positives, false positives, true negatives, and false negatives, as well as formulas for calculating disease-free individuals, diseased individuals, and revising estimates of diagnostic test performance.

Typology: Slides

2012/2013

Uploaded on 11/21/2013

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Diagnosis II

Conditional Probabilities

(T

(T

-^ )

(D

True

Positive

(D

-^ )

False

Negative

True

Negative

FalsePositive

Gold Standard

Clinical

Test

I

nterpretation of Diagnostic

Data

(T
(T
(D
+ ) A
(D

C^

B^ D

P (T

-^

^
D
P (T

-^

^
D
+^ )

OR C / (A + C)D / (B + D)

I

nterpretation of Diagnostic

Data

(T
(T
(D
+ ) A
(D

C^

B^ D

(A + D)

I

nterpretation of Diagnostic

Data

(T
(T
(D
+ ) A
(D

C^

B^ D

P ( D

-^

^
T^
-^ )
(C + D)

OR D

Revising Estimates of

Diagnostic Test Performance (T

(T
(D
(D

(^2281292)

  1. Select an arbitrary sample size.2. Based on prevalence, calculate the 1600

diseased individuals.

  1. Calculate the disease-free individuals.4. Calculate D

+^ based on fixed sensitivity.

  1. Calculate D -^ based on fixed specificity.

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