KARCH'S FOCUS ON PHARMACOLOGY 8TH ED. | CHAPTER 1 EXAM QUESTIONS AND ANSWERS 100% ACCURATE, Exams of Pharmacology

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KARCH'S FOCUS ON PHARMACOLOGY

8TH ED. | CHAPTER 1 EXAM QUESTIONS

AND ANSWERS 100% ACCURATE!!

Clinical Pharmacology - ANSWER the study of drugs used to treat, prevent, or diagnose disease.

Phase I drug studies involve - ANSWER healthy human volunteers who are often paid for their participation.

The generic name of a drug is - ANSWER the original name assigned to the drug at the beginning of the evaluation process.

An orphan drug is a drug that - ANSWER has been tested but is not considered to be financially viable.

The FDA pregnancy categories were used - ANSWER to indicate a drug's potential or actual teratogenic effects.

The storing, prescribing, and distributing of controlled substances - drugs that are more apt to be addictive - are monitored by - ANSWER the DEA.

Healthy young women are not usually involved in phase I studies of drugs because - ANSWER females are more apt to suffer problems with ova, which are formed only before birth.

A patient has been taking fluoxetine (Prozac) for several years, but when picking up the prescription this month found that the tablets looked different and became concerned. The nurse, checking with the pharmacist, found that fluoxetine had just become available in the generic form and the prescription had been filled with the generic product. The nurse should tell the patient - ANSWER that the law requires that prescriptions be filled with the generic form if available to cut down the cost of medications.

When teaching a patient about OTC drugs, which points should the nurse include? - ANSWER c. Many of these drugs were once prescription drugs but are now thought to be safe for use without a prescription when used as directed.

d. Reading the label of these drugs is very important; the name of the active ingredient is prominent; you should always check the ingredient name.

explanation? - ANSWER a. A generic drug is a drug that is sold by the name of the ingredient, not the brand name.

c. Generic drugs are not available until the patent expires on a specific drug.

d. Generic drugs are usually cheaper than the well-known brand names, and some insurance companies require that you receive the generic drug if one is available.

f. Your physician may want you to have the brand name of a drug, not the generic form, and DAW will be on your prescription form.

A nurse is teaching a client about the pharmacotherapeutics of the hormone replacement therapy that the client has been prescribed. What topic should the nurse address? - ANSWER the effect of the drug on the client's body.

The nurse knows that a client is at high risk for developing drug tolerance because the client will be taking which drug for a long period of time? - ANSWER Hydromorphone (Dilaudid) for pain

The nurse is caring for a client who is exhibiting adverse medication effects. The nurse should recognize that adverse effects can be extensions of: - ANSWER the primary action of a drug.

The birth defects associated with thalidomide (Thalomid) resulted in legislation known as the: - ANSWER Kefauver-Harris Act of 1962.

Which Food and Drug Administration (FDA) pregnancy category indicates that animal studies on the drug have shown adverse fetal effects, but there are no adequate studies in humans? - ANSWER category C

People and companies that are legally empowered to handle controlled substances must follow what procedures? (Select all that apply.) - ANSWER Keep accurate records of all transactions. Provide for secure storage of controlled substances. Be registered with the DEA.

A drug was introduced to the market, where it was well received, and the nurse has learned that generic equivalents will soon be released. The nurse should understand what implication of this fact? - ANSWER The manufacturer's patent on the drug has recently expired.

The processes that largely determine serum drug levels, adverse effects, and other important aspects of drug therapy is known by what term? - ANSWER Clearance

How may drugs be prescribed and dispensed? - ANSWER by generic or trade name

Which article of legislation specified that drugs must carry the label "may not be distributed without a prescription." - ANSWER Durham-Humphrey Amendment

When asked by a client about the generic name of a drug, what is the nurse's best response? - ANSWER "The generic name is the official name given by the U.S. Food and Drug Administration."

Drugs are classified according to what features? - ANSWER therapeutic uses

A nurse has been administering a drug to a client intramuscularly (IM). The health care provider discontinued the IM dose and wrote an order for the drug to be given orally. The nurse notices that the oral dosage is considerably higher than the parenteral dose and understands that this due to: - ANSWER First-pass effect

The breakdown of oral drugs in the liver immediately after absorption is known as which of the following? - ANSWER First-pass effect

A patient with a recent diagnosis of acute renal failure has a long-standing seizure disorder which has been successfully controlled for several years with antiseizure medications. The nurse should recognize that the patient's compromised renal function will likely - ANSWER Increase the half life of medications that are metabolized by the kidney.

A drug is undergoing Phase III testing. During this phase, what activity will take place? - ANSWER The drug will be given to a large number of subjects.

A newly pregnant client has been taking a category A drug for several years. What should the nurse instruct the client about this drug? - ANSWER "Discuss this with your care provider, but you'll likely be able to keep taking it."

The nurse reviews various legislation related to drug therapy, including the Kefauver-Harris Act. What aspect of drug therapy is most directly affected by this legislation? - ANSWER the drug testing process overseen by the FDA

When using Internet sites to obtain drug information, it is imperative that a nursing student takes which action to ensure client safety? - ANSWER Critically assess the quality of the website.

Which statement is true regarding generic and trade names of drugs? - ANSWER Generic names are independent of the manufacturer.