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TERM 1
Cells of the Early Immune Response (innate)
DEFINITION 1 Neutrophil: phagocytosis (bactericidal) most abundant in blood andinfectedtissues 1st to respond die quickly Macrophage:phagocytosis (bactericidal) in tissues and organsEosinophil: killing parasitesMast cell: releaseinflammatorymediatorsNatural killer cell: lyse virally infected cells (lymphocyte cells) TERM 2
innate immunity
DEFINITION 2 first line of defense, look for things that are different to target with receptors TERM 3
adaptive immunity
DEFINITION 3 The adaptive immune system, also known as the specific immune system, is composed of highly specialized, systemic cells and processes that eliminate or prevent pathogenic growth.Recognize antigens TERM 4
toll like receptors
DEFINITION 4 TLR's are on the surface of all cells and when they detect microbes they release cytokines TERM 5
where are receptors of the innate immunity
system encoded?
DEFINITION 5 germlineall of the receptors are the same (cloned)no memory
TERM 6
lymphocyte receptors are encoded where?
DEFINITION 6 recombinant receptor genesreceptors are different and varioushas immunologic memory which is similar to how innate receptors function TERM 7
Most common entry point of microbes?
DEFINITION 7 skingastrointestinal tractrespiratory tract TERM 8
how do epithelial cells kill bacteria?
DEFINITION 8 produce peptide antibioticshave intraepithelial lymphocytes (T cells) TERM 9
cytokines
DEFINITION 9 Cytokines are small cell-signaling protein molecules that are secreted by numerous cells and are a category of signaling molecules used extensively in intercellular communication. colony stimulating factors (signal for more fighting cells to be made)stimulate proliferation and maturation of bone marrow stem cells TERM 10
monocyte cells mature into what?
DEFINITION 10 macrophagesmonocytes remain in the blood and when mature migrate to tissues and organs
