LIPIDS METABOLISM TABLE CHEAT SHEET, Cheat Sheet of Biochemistry

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Table 111-1. Key Enzymes of Long Chain Fatty Acid Catabolism Stage of j Non-Fatty Acid Utilization Location Enzyme Reactants [Products Comments | | Endoplasmic Fatty Acyl CoA ATP AMP Subsequent Activation reticulum, {Synthetase ray’ |op, * [hydrolysis of PP) Out. Mito. Mem. |(Thiokinase} ' draws this rxn Transport Mito. | gyter into Carnitine Acyl |carni- Transferase | |tine CoA Control point for B-oxidation 8-Oxidation | Mitochondrial Mitochondria|Memb.| jpner [Carnitine Acyl |—,, — |Carni- Transferase Il tine i Acyl CoA FAD- |FADH»-| Diffe Dehydrogenase |protein | protein for ditt. acyl i L-B-hydroxy- Matrix acyl CoA + Dehydrogenase NAD NADH Thiglase CoA Table I11-2. Comparison of Mitochondrial Carnitine Acyl Transferases CAT I CAT Il Location in mitochondrial membrane Outer membrane Inner surface of inner membrane Substrates Acyl CoA, carnitine Acyl carnitine, CoA Products Acyl carnitine, Cod Acyl CoA, carnitine Inhibitor Malonyl CoA