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Mechanical Ventilation: Understanding the Equation of Motion and COVID-19 Implications, Exams of Medical Sciences

A comprehensive overview of mechanical ventilation, including the plan of action, the equation of motion that represents the total pressure required to overcome resistance and elastance, and the specific considerations for covid-19 patients. It discusses the historical development of mechanical ventilation, from the use of negative pressure in the iron lung to the modern positive pressure approach. The document also addresses the role of non-invasive ventilation, its limitations, and the recommendations for covid-19 patients. This information is valuable for healthcare professionals, students, and researchers interested in understanding the principles and applications of mechanical ventilation, particularly in the context of the covid-19 pandemic.

Typology: Exams

2023/2024

Available from 08/27/2024

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Mechanical Ventilation
Plan of action for mechanical ventilation - correct answer Plan is not to cure the patient but to buy
time for the medical team to implement proper treatment options to resolve patients underlying
condition and provide patient time to heal until such a time that they're able to breathe on their
own without the mechanical ventilator.
Mechanical Ventilation - correct answer the need for mechanical ventilation is based on the
equation of motion.
Equation of motion - correct answer represents the total amount of pressure that needs to be
generated to overcome the combination of pressure due to resistance and the pressure due to
elastance.
equation of motion example - correct answer an increase in resistance, such as asthma
exacerbation, would require increased work to over this resistance.
a condition such as intra-abdominal hypertension and ARDS would result in increased work
required to overcome the stiffness of the chest wall or the lung which is a component of the
respiratory system elastance.
Mechanical Ventilation continued - correct answer in some cases, increased work can be due to gas
exchange issues that are not directly related to resistance and elastance.
mechanical ventilation and covid-19 - correct answer there have been reports of patients with
covid-19 having a high respiratory drive with normal resistance and compliance. and compliance is
just the inverse of elastance.
Mechanical ventilation hypoxemia - correct answer hypoxemia and hypercarbia can also increase
drive without increased work.
covid-19 patients that require mechanical ventilation are presenting profound hypoxemia
equation of motion continued - correct answer spontaneous breathing patients generate negative
pressure to do this work.
and the first widely used type of mechanical ventilation to assist or take over this work was based
on the concept of negative pressure - the iron lung.
Modern mechanical ventilation - correct answer modern mechanical ventilation no longer uses
negative pressure, instead it generates positive pressure to overcome this work. non-invasive
ventilation can be provided via facemask.
Noninvasive ventilation - correct answer therapy that has been shown to significantly reduce the
need for intubation and mortality in patients with chronic lung and heart disease but has
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Mechanical Ventilation

Plan of action for mechanical ventilation - correct answer Plan is not to cure the patient but to buy time for the medical team to implement proper treatment options to resolve patients underlying condition and provide patient time to heal until such a time that they're able to breathe on their own without the mechanical ventilator. Mechanical Ventilation - correct answer the need for mechanical ventilation is based on the equation of motion. Equation of motion - correct answer represents the total amount of pressure that needs to be generated to overcome the combination of pressure due to resistance and the pressure due to elastance. equation of motion example - correct answer an increase in resistance, such as asthma exacerbation, would require increased work to over this resistance. a condition such as intra-abdominal hypertension and ARDS would result in increased work required to overcome the stiffness of the chest wall or the lung which is a component of the respiratory system elastance. Mechanical Ventilation continued - correct answer in some cases, increased work can be due to gas exchange issues that are not directly related to resistance and elastance. mechanical ventilation and covid- 19 - correct answer there have been reports of patients with covid-19 having a high respiratory drive with normal resistance and compliance. and compliance is just the inverse of elastance. Mechanical ventilation hypoxemia - correct answer hypoxemia and hypercarbia can also increase drive without increased work. covid-19 patients that require mechanical ventilation are presenting profound hypoxemia equation of motion continued - correct answer spontaneous breathing patients generate negative pressure to do this work. and the first widely used type of mechanical ventilation to assist or take over this work was based on the concept of negative pressure - the iron lung. Modern mechanical ventilation - correct answer modern mechanical ventilation no longer uses negative pressure, instead it generates positive pressure to overcome this work. non-invasive ventilation can be provided via facemask. Noninvasive ventilation - correct answer therapy that has been shown to significantly reduce the need for intubation and mortality in patients with chronic lung and heart disease but has

demonstrated high failure rates and lacks recommendations for patients in hypoxemic failure without chronic lung or heart disease. and for this reason, not recommended as an approach to avoid intubation in covid-19 patients.