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Medication List for Postpartum Bleeding: Oxytocin, Misoprostol, and Methylergonovine, Study notes of Nursing

Information on three medications used to reduce or prevent postpartum bleeding: oxytocin (pitocin), misoprostol (cytotec), and methylergonovine (methergine). For each medication, the document lists the name, purpose, safe dosage, side effects, and patient education. Nurses can use this list to make clinical judgments about medication administration and monitor clients for adverse reactions.

What you will learn

  • What are the side effects of Misoprostol (Cytotec) that a nurse should monitor for?
  • How does Methylergonovine (Methergine) help to prevent or reduce postpartum bleeding?
  • What are the specific findings that support the need for Oxytocin (Pitocin) medication?

Typology: Study notes

2021/2022

Uploaded on 09/26/2022

joyce-amankwah
joyce-amankwah 🇺🇸

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Clinical Judgment Medication List
List specific findings (assessments/cues, VS, labs, etc.) that support the need for this medication.
Medication
name
Purpose of the medication
for THIS client
How will the nurse know there is a
problem, or the client is not tolerating
the medication?
How will the nurse know the
medication is effective? Patient/ Family Education
GENERIC:
oxytocin
(synthetic
injection)
TRADE:
Pitocin
CLASSIFICATION:
Therapeutic
class: Oxytocic
Pharmacologic
class:
Exogenous
hormones
Is the dose safe? YES
To reduce
postpartum bleeding
after expulsion of
placenta
Adults:110 to 40 units
IV infused at rate
needed to sustain
uterine contraction
and control uterine
atony. Also, may give
10 units IM after
delivery of placenta
Monitor fluid intake and
output. Antidiuretic effect
may lead to1fluid overload,
seizures, and coma from
water intoxication.
Increase amount of bleeding
Reduces amount of
bleeding
Instruct patient to
promptly report adverse
reactions (site
irritation,1nausea,
bleeding, blurred vision,
difficulty
speaking,1wheezing,
itching, swelling)
GENERIC:
Misoprostol
TRADE:
Cytotec
CLASSIFICATION:
Therapeutic
class: Antiulcer
drugs
Pharmacologic
class:
Prostaglandin
E1 analogues
Is the dose safe? NO
To prevent NSAID-
induced gastric ulcer
in patients at high
risk for
complications from
gastric ulcer and in
patients with history
of NSAID-induced
ulcer
Misoprostol is another
prostaglandin that
increases uterine tone
and decreases
postpartum bleeding.
Misoprostol is effective
in the treatment of
postpartum
Associated side effects may
include shivering and fever
Vaginal bleeding or
spotting may occur
Postpartum
hemorrhage should
decrease within
minutes of use
Remind female patient
who is pregnant that
drug may cause
miscarriage, premature
birth, or birth defects,
often with potentially
life-threatening
bleeding
pf2

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Clinical Judgment Medication List

List specific findings (assessments/cues, VS, labs, etc.) that support the need for this medication.

Medication name

Purpose of the medication for THIS client

How will the nurse know there is a problem, or the client is not tolerating the medication?

How will the nurse know the medication is effective? Patient/ Family Education

GENERIC:

 oxytocin (synthetic injection)

TRADE:  Pitocin

CLASSIFICATION:  Therapeutic class: Oxytocic  Pharmacologic class: Exogenous hormones

Is the dose safe? YES

 To reduce postpartum bleeding after expulsion of placenta Adults: 10 to 40 units IV infused at rate needed to sustain uterine contraction and control uterine atony. Also, may give 10 units IM after delivery of placenta

 Monitor fluid intake and output. Antidiuretic effect may lead to fluid overload, seizures, and coma from water intoxication.  Increase amount of bleeding

 Reduces amount of bleeding

 Instruct patient to promptly report adverse reactions (site irritation, nausea, bleeding, blurred vision, difficulty speaking, wheezing, itching, swelling)

GENERIC:

 Misoprostol

TRADE:  Cytotec CLASSIFICATION:  Therapeutic class: Antiulcer drugs  Pharmacologic class: Prostaglandin E1 analogues

Is the dose safe? NO

 To prevent NSAID- induced gastric ulcer in patients at high risk for complications from gastric ulcer and in patients with history of NSAID-induced ulcer  Misoprostol is another prostaglandin that increases uterine tone and decreases postpartum bleeding. Misoprostol is effective in the treatment of postpartum

 Associated side effects may include shivering and fever  Vaginal bleeding or spotting may occur

 Postpartum hemorrhage should decrease within minutes of use

 Remind female patient who is pregnant that drug may cause miscarriage, premature birth, or birth defects, often with potentially life-threatening bleeding

Clinical Judgment Medication List

List specific findings (assessments/cues, VS, labs, etc.) that support the need for this medication.

Medication name

Purpose of the medication for THIS client

How will the nurse know there is a problem, or the client is not tolerating the medication?

How will the nurse know the medication is effective? Patient/ Family Education

hemorrhage, but side effects may limit its use. It can be administered sublingually, orally, vaginally, and rectally

GENERIC:

Methylergonovine

TRADE:  METHERGINE CLASSIFICATION:  Ergot alkaloids

Is the dose safe? NO

 It is used to stop or treat bleeding that happens after a birth.

 Increased amount of bleeding with use

 Prevention/ Reduction of postpartum bleeding

 It works by increasing the rate and strength of contractions and the stiffness of the uterus muscles. These effects help to decrease bleeding.  Do not drive, use machinery, or do anything that needs alertness until you can do it safely  Do not breast-feed within 12 hours after taking methylergonovine. Methylergonovine may pass into breast milk in small amounts and could affect a nursing baby.

GENERIC:

TRADE:

CLASSIFICATION:

Is the dose safe?