Mouse Party Worksheet
Go through the video “Mouse Party” and fill in this worksheet. You will fill in the neurotransmitters involved, how the drug acts on
neurotransmission and the effects users feel who take the drug.
Drug Neurotransmitter(s) involved How the drug effects
neurotransmission
How does the user feel when
taking this drug?
Heroin
Dopamine Heroin mimics natural opiates to
bind to opiate receptors, which
turns off dopamine inhibition.
Dopamine floods into the synapse
Sedation
Ecstasy
Serotonin Mimics serotonin, transporter
pushes serotonin out of the cell
and keeps ecstasy. The cell
becomes overstimulated
Mood & sleep
“love drug”
Marijuana
Cannabinoid
Anandamide
THC mimics anandamide and
binds to cannabinoid receptors.
Inhibition is turned off and
dopamine gets into the synapse
Relaxed and calm
Methamphetamine
Dopamine Meth mimics dopamine, so meth
is taken into the cell by dopamine
transporters. Meth pushes
dopamine out into the synapse
Intense pleasure and
overstimulation
Alcohol
Gaba
Glutamate
Interacts with GABA receptors,
then binds to glutamate to
prevent glutamate from exiting
the cell
Sad
Aggressive
Cocaine
Dopamine Leaves dopamine trapped in the
synaptic cleft
Fidgety
