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A comprehensive set of questions and answers related to the respiratory system, covering various aspects of anatomy, physiology, and common respiratory conditions. It includes detailed explanations for each answer, making it a valuable resource for students studying respiratory health.
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Surfactant correct answer: Coats the inside layer of alveoli to reduce surface tension Visceral Pleura correct answer: Inner, medial layer Attached to lung parenchyma Parietal Pleura correct answer: Outer, lateral layer Will adhere the 2 layers for chest and lung expansion Residual Volume correct answer: Volume of air remaining in lungs after the max exhalation Vital Capacity correct answer: The maximal amount of air that can be moved in and out of lungs with breaths Can be altered by lung disease, size of thorax, amount of fluid in lungs Central (Primary Control) correct answer: Chemoreceptors in the brain stem-> —> elevated CO2, elevated H+ in the CSF Hypercapnia is a major stimulus for the healthy CNS respiratory center
Peripheral (Secondary Control) correct answer: Chemoreceptors in carotid artery and aortic body —-> decreased oxygen concentration in blood is major stimulus Oxygen levels must be low (60 torr) for activation Sinusitis correct answer: Bacterial infection secondary to a cold or allergy that obstructs sinus drainage Cause: Strep, Staph, heamophilus Influenza Signs/Sx: Nasal congestion, HA, Low grade fever Laryngotracheobronchitis (Croup) correct answer: Viral infection usually affects children 1-2 years old Cause: parinfluenza virus and adreno virus Signs/Sx: URI (cough, fever, rhinitis) Worse at night Obstruction of airway by inflammation and exudate Barking cough —-> inspiratory stridor especially when active Bronchiolitis (RSV) correct answer: Common infection in young children 2- 12 months Cause: Respiratory syncytial virus, oral droplets Fall/Winter months, Second hand smoke
Cause: Usually viruses, if progress past 10-14 days, may develop bacterial infection Signs/Sx: Nonproductive cough easily triggaered by environment changes, wheezes Influenza (Respiratory Influenza) correct answer: Viral Infection characterized by high fever (>102) and cough Signs/Sx: Sudden high fever, marked fatigue, body aches
Severe Acute Respiratory Distress Syndrome (SARS) correct answer: Cause: SARS-CoV, transmitted suspected by fecal/oral ——> incubation 2-7 days First stage: Flu-like syndrome, fever, HA, myalgia, chills Second Stage: Marked dyspena, high mortality Pathology: inflammation and alveolar congestion leads to decreased oxygen perfusion, hypoxia, thrombopenia, lymphopenia, elevated C-protein, Elevated liver enzymes Middle Eastern Respiratory Syndroms (MERS) (Camel Flu) correct answer: Cause: MERS-CoV transmitted from camels Transmission: respiratory droplet —-> incubation 2-14 days Pathophysiology and treatment is similar to SARS Tuberculosis (TB) correct answer: Cause: Mycobacterium tuberculosis (acid- fast, aerobic bacteria)
Systemic signs: weight loss, anemia, fatigue, metastasis (bone pain/fractures) Non-Small Cell Carcinoma (NSCLC) correct answer: Comprise about 80% of all lung cancers further divided into squamous cell, adenocarcinoma, large cell significant genotyping for personalized therapy NeuroEndocrine correct answer: Includes small-cell carcinoma and large neuroendocrine carcinoma
-Primiarily affects the lungs and pancreas, characterized by obstructions Lung disease, but also affects pancreas and GI tract Asthma correct answer: Chronic lung disorder characterized by periodic episodes of severe, reversible bronchial obstruction in persons with hypersensitive airways. Cardinal Sign: FEV1 measurement Pathophysiology: inflammation of mucosa with edema and increased mucus production -Bronchial hyper-responsiveness
Partially irreversible, progressive, and eventually leads to respiratory failure due to hypoxia, hypercapnia, for pulmonale Emphysema correct answer: Pathophysiology: Destruction of alveolar walls and septae
Signs/Sx: Blue Bloater, constant productive cough, thick secretions, hypoxia and cyanosis, dyspena, pulmonary hypertension, JVD, peripheral edema Aspiration correct answer: A restrictive disorder, decreased lung expansion, alveoli become inflamed, and gas diffusion is impaired Etiology: decreased LOC, NG tube feedings Complications: inflammation, bronchospasm and lost cilliary function Ateletctasis correct answer: The non-aeration collapse of part of a lung leading to decreased gas exchange and hypoxia Pathophysiology: When the alveoli become airless, they shrivel up as elastic recoil shrinks their shape -Both ventilation and perfusion are affected Etiology: Compression—> tumor—> pleural fluid/effusion Absorption—> hypoventilation from obstruction Surfactant Impairment/Higher surface tension—> ARDS—> Pulm edema Signs/Sx: Dyspena, tachycardia, tachypena, absent breath sounds Pleural Effusion correct answer: Excessive fluid in the pleural cavity
Etiology: pulmonary edema, pulmonary embolus, COPD, and ARDS Mismatch correct answer: Any pulmonary condition that leads to deoxygenated blood passing through pulmonary artery circuit and surviving into the pulmonary vein circuit Pulmonary Edema correct answer: Pathophysiology: Fluid collection in the alveoli and interstitial area of lung. It greatly reduces oxygen diffusion into the blood.
Pathophysiology: Ischemia of distal tissue results in V/Q mismatch, hypoxemia, and can lead to lung infarction Signs/Sx: Tachycardia, anxiety, chest pain ARDS correct answer: Pathophysiology: Inflammatory response, increased capillary permeability that will lead to pulmonary edema, decreased oxygen diffusion, hypoxemia Etiology: severe shock or sepsis, inhaled toxins, aspiration pneumonia, lung trauma, pulmonary emboli Signs/Sx: Accesory muscle use, crackles, rales, cyanosis, respiratory failure Dysphagia correct answer: Difficulty Swallowing Neuro deficit (CN V,VII,IX,X,XII) Muscular disorder Obstructive: Mechanical obstruction Risks: Aspiration Hiatal Hernia correct answer: Protrusion of part of the stomach through opening of diaphragm Contributing factors: shortening of esophagus, weakness of diaphragm, and increased abdominal pressure Signs/Sx: GERD, heart burn, dysphagia, mild, persistent chest pain after meals
Dumping Syndrome correct answer: Pathophysiology: Large amounts of ingested food is quickly dumped into the intestines.
Etiology: premature activation of proenzyme trypsinogen into trypsin Signs/Sx: severe abdominal pain radiating to the back Chronic Inflammatory Bowel Disease (Crohn's Disease and Ulverative Colitis) correct answer: Etiology: genetic and environmental factors appear to be involved Crohn's Disease correct answer: Skip lesions- inflammation begins in intestinal submucosa and spreads in discontinuous pattern Manifestations: soft, semi-formed stools, Marlena, RLQ pain, anemia, fatigue, weight loss Adhesions or fistulas are complications Ulverative Colitis correct answer: Pathophysiology: Inflammation of the mucosa and submucosa at the base of the crypts of liberkuhn, Granular tissue is susceptible to bleeding Sites: starts in the rectum and advances superionly up colon Signs/Sx: Frequent, watery, blood containing diarrhea, abdominal cramping, tense us, rectal bleeding.