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A comprehensive overview of various medications and treatments used for mental health disorders, including anxiety disorders, obsessive-compulsive disorder (ocd), trauma and dissociative disorders, eating disorders, insomnia, narcolepsy, and restless leg syndrome. It includes questions and answers related to the use, side effects, and contraindications of different medications, as well as non-pharmacological treatment options. Particularly useful for students studying nursing or related healthcare fields.
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Acute anxiety - ANSWER -First line for acute panic may be short term benzo use. short acting benzos cause rebound anxiety and are the most abused Benzodiazepines - ANSWER -Withdrawal can be dangerous, even deadly. Stopping abruptly is not advised. Symptoms of agitation, tension, irritability, and sz. may occur anxiety disorders - ANSWER -psychological disorders characterized by distressing, persistent anxiety or maladaptive behaviors that reduce anxiety anxiety disorders treatment - ANSWER --non-activating antidepressants area good place to start. for this disorder first line treatment anxiety disorders - ANSWER -SSRI- Fluoxetine (Prozac), sertraline (Zoloft), and paroxetine (Paxil) TCAs often effective but with riskier SE may interfere with psychotherapy in TX of AD - ANSWER -Benzodiazepines- short acting Alprazolam are most abusable Rapid onset BZD - ANSWER -used for acute panic disorder BZD with long half- life (20-80 hours) - ANSWER -Diazepam (avoid in elderly) BEERS criteria - ANSWER -A list of medications that are generally considered inappropriate when given to elderly people BEERS criteria - ANSWER -Identifies High Risk Meds to Generate Wide List of Meds That Should be Avoided
The "Beers Criteria for Potentially Inappropriate Medication Use in Older Adults", commonly called the Beers List, are guidelines for healthcare professionals to help improve the safety of prescribing medications for older adults. concomitant with pharmacological tx in AD - ANSWER -Psychotherapy First line for specific phobias like clowns, blood, animals - ANSWER -Psychotherapy medications not all that helpful for specific phobias OCD treatment - ANSWER -SSRI and CBT BZD in treatment of OCD - ANSWER -Xanax, Valium, Klonipin Trauma and Dissociative Disorders - ANSWER -Consider and treat and comorbid disorders as well Trauma and Dissociative Disorders first line pharmocology - ANSWER -Antidepressants Psychotherapy are treatment of choice Dissociative disorders - ANSWER -the degree of insight the patient has is crucial to the outcome of psychotherapy DID- Dissociative identity disorder - ANSWER -may consider multi pronged approach to treatment but strongly linked to childhood trauma so treating underlying PTSD s/s is often helpful DID - ANSWER -discourage use of BZD DID - ANSWER -beta blockers and alpha blockers useful for reducing sympathetic nervous system activation
R - Reproductive/Sexual dysfunction I - Insomnia; antidepressants used in eating disorders - ANSWER -SSRIs (high doses), TCAs TCAs - ANSWER -tricyclic antidepressants TCA side effects - ANSWER -3Cs - cardiotoxicity, coma, convulsions antihistamine - weight gain, sedation anti adrenergic - orthostasis, reflex tachy, arrythmias, wide QRS/QT/PR anti-muscarinic - dry mouth, constipation, urinary retention, blurred vision, tachycardia, narrow angle glaucoma serotoninergic side effects - erectile/ejaculatory dysfunction in males, anorgasmia in females lethal in overdose weight gain seizures meds to treat Binge Eating Disorders - ANSWER -Vyvanse (lisdexamfetamine) pharmacology indications for anorexia nervosa - ANSWER -No medications are approved to treat anorexia because none has been found to work very well. However, antidepressants or other psychiatric medications can help treat other mental health disorders you may also have, such as depression or anxiety. pharmacotherapy indications for bulimia nervosa - ANSWER -The only antidepressant specifically approved by the Food and Drug Administration to treat bulimia is fluoxetine (Prozac), a type of selective serotonin reuptake inhibitor (SSRI), which may help even if you're not depressed. Binge Eating Disorder Treatment - ANSWER --responds more rapidly to treatment than other eating disorders
-self-help groups -learn to eat only when hungry -idenify personal needs -find healthful ways to express its emotions Binge Eating Disorder Treatment - ANSWER -CBT Contraindicated in eating disorders due to eating disorders having elevated risk of sz - ANSWER -Buproprion- "poor man's cocaine" hallmark of toxicity is sz. Buproprion contraindications - ANSWER -increases risk of seizures, anorexia, bulimia. avoid with any condition that increases seizure-- abrupt etoh withdrawl, head injuries. antidepressants in binge eating disorders - ANSWER -SSRI are first line if you are going to choose an antidepressant to treat as they are often very co-morbid with depression and anxiety disorders If a patient has both eating disorder and comorbid depression or anxiety, treatment should follow indications for the comorbidity- ex. if they have OCD comorbid with anorexia nervosa then what ( ?) would be indicated for the OCD should be your choice - ANSWER -SSRI Insomnia treatment - ANSWER -nonpharmacologic treatments for insomnia include sleep hygeine, stimulus control, relaxation, sleep restriction, and cognitive behavioral therapy. Stimulus control focuses on eliminating stimulating bedroom activities and getting into bed only when sleepy. benzodiazepine hypnotics (tx of insomnia) - ANSWER -Diazepam, Midazolam, Zolazepam, Triazolam, flurazepam, temazepam Potentiates the inhibitory action of GABA ( inhibitory neurotransmitter that reduces feelings of fear and anxiety). Activation of the receptor causes an influx of Cl- ion movement into the neuron and hyperpolarization and inhibition of membrane depolarization Benzodiazepine hypnotics affect - ANSWER -REM sleep, tolerance, risk of abuse, rebound insomnia
Narcolepsy treatment - ANSWER -Modafinil (Provigil) Cataplexy (narcolepsy) - ANSWER -loss of muscle control & sudden REM sleep during waking hours emotionally triggered GHB sodium oxybate - ANSWER -CIII What is GHB - ANSWER -Sodium oxybate, sold under the brand name Xyrem among others, is a medication used to treat two symptoms of narcolepsy: sudden muscle weakness and excessive daytime sleepiness. Treatment of restless leg syndrome - ANSWER -Mild/intermittent sxs:
psychopharmacologic treatment in sleep/ wake disorders - ANSWER -Be mindful of the onset and half lives of these meds Benzodiazepine half life - ANSWER -alprazolam Xanax 12-15 hours lorazepam Ativan 10 to 20 hours oxazepam 6 to 20 hours Flurazepam half life - ANSWER -2.3 hours Zoldipem half life - ANSWER -2.5- 3 hours Zaleplon half life - ANSWER -1 hour rebound insomnia - ANSWER -in a person with insomnia, the worsened sleep problems that can occur when medications are used to treat insomnia and then withdrawn rebound insomnia and effect on REM sleep - ANSWER -Like rebound sleep in general, REM rebound sleep3 usually occurs in response to sleep deprivation or stress. REM rebound can also occur in response to a suppression of REM sleep in particular Narcolepsy treatment options - ANSWER -Stimulants. Drugs that stimulate the central nervous system are the primary treatment to help people with narcolepsy stay awake during the day. modafinil (Provigil) or armodafinil (Nuvigil) first for narcolepsy
Some SNRIs, such as venlafaxine (Effexor XR), duloxetine (Cymbalta, Drizalma Sprinkle), milnacipran (Savella) and desvenlafaxine (Pristiq), may help relieve chronic pain. People with chronic pain often develop depression along with their chronic pain. Venlafaxine and duloxetine offer the advantage of being effective for depression and anxiety at the same dosages useful for treating pain.