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NUR 521 Exam 3 with correct answers, Exams of Nursing

NUR 521 Exam 3 with correct answers

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2024/2025

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NUR 521 Exam 3 with correct answers
natural|immunity|(innate|or|native)|-|verified|answerstype|of|immunity|that|includes|physical|barriers|
(e.g.,|skin),|phagocytic|cells,|and|natural|killer|cells.|All|of|these|factors|are|present|before|exposure|to|a|
particular|infectious|agent,|and|all|respond|nonspecifically.
specific|acquired|immunity|-|verified|answersImmunity|in|which|responses|occur|only|after|exposure|to|a|
foreign|substance.|Objective|is|to|destroy|antigens
Antigens|-|verified|answersThe|foreign|substances|that|induce|specific|responses|in|specific|acquired|
immunity
Cell-mediated,|Humoral|(antibody-mediated)|-|verified|answersthe|two|classes|of|specific|acquired|
immunity
Cell-mediated|immunity|-|verified|answersrefers|to|immune|responses|in|which|targets|are|attacked|
directly|by|immune|system|cells—specifically,|cytolytic|T|cells|and|macrophages
Humoral|immunity|-|verified|answersrefers|to|immune|responses|that|are|mediated|by|antibodies.
B|lymphocytes|-|verified|answershave|the|job|of|making|antibodies.|Hence|mediates|humoral|immunity.|
produced|in|the|bone|marrow.
Cytolytic|T|Cells|-|verified|answersattack|and|kill|target|cells|directly,|mature|in|the|thymus
Helper|T|cells|-|verified|answerscontribute|to|the|immune|response|in|three|ways:|(1)|they|have|an|
essential|role|in|antibody|production|by|B|cells;|(2)|they|release|factors|that|promote|type|IV|sensitivity|
reactions,|also|known|as|delayed-type|hypersensitivity|(DTH);|and|(3)|they|participate|in|the|activation|of|
cytolytic|T|cells.
Are|the|immune|cell|that|HIV|attacks|
Mature|in|the|thymus
Macrophages|-|verified|answersPresent|in|all|organs|and|tissues,|primary|role|is|phagocytosis,|(1)|they|
are|required|for|activation|of|T|cells|(both|helper|T|cells|and|cytolytic|T|cells),|(2)|they|are|the|final|
mediators|of|DTH,|and|(3)|they|phagocytize|cells|that|have|been|tagged|with|antibodies
Dendritic|Cells|-|verified|answersperform|the|same|antigen-presenting|task|as|do|macrophages,|but|do|
not|act|as|scavengers
Mast|cells|-|verified|answersThese|cells|mediate|immediate|hypersensitivity|reactions,|derived|from|
basophils,|concentrated|in|the|skin|and|other|soft|tissues,|release|histamine,|heparin,|and|other|
compounds|that|cause|the|symptoms|of|immediate|hypersensitivity
Basophils|-|verified|answersThese|cells|mediate|immediate|hypersensitivity|reactions,|circulate|in|the|
blood,|release|histamine,|heparin,|and|other|compounds|that|cause|the|symptoms|of|immediate|
hypersensitivity
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NUR 521 Exam 3 with correct answers

natural|immunity|(innate|or|native)|-|verified|answerstype|of|immunity|that|includes|physical|barriers| (e.g.,|skin),|phagocytic|cells,|and|natural|killer|cells.|All|of|these|factors|are|present|before|exposure|to|a| particular|infectious|agent,|and|all|respond|nonspecifically. specific|acquired|immunity|-|verified|answersImmunity|in|which|responses|occur|only|after|exposure|to|a| foreign|substance.|Objective|is|to|destroy|antigens Antigens|-|verified|answersThe|foreign|substances|that|induce|specific|responses|in|specific|acquired| immunity Cell-mediated,|Humoral|(antibody-mediated)|-|verified|answersthe|two|classes|of|specific|acquired| immunity Cell-mediated|immunity|-|verified|answersrefers|to|immune|responses|in|which|targets|are|attacked| directly|by|immune|system|cells—specifically,|cytolytic|T|cells|and|macrophages Humoral|immunity|-|verified|answersrefers|to|immune|responses|that|are|mediated|by|antibodies. B|lymphocytes|-|verified|answershave|the|job|of|making|antibodies.|Hence|mediates|humoral|immunity.| produced|in|the|bone|marrow. Cytolytic|T|Cells|-|verified|answersattack|and|kill|target|cells|directly,|mature|in|the|thymus Helper|T|cells|-|verified|answerscontribute|to|the|immune|response|in|three|ways:|(1)|they|have|an| essential|role|in|antibody|production|by|B|cells;|(2)|they|release|factors|that|promote|type|IV|sensitivity| reactions,|also|known|as|delayed-type|hypersensitivity|(DTH);|and|(3)|they|participate|in|the|activation|of| cytolytic|T|cells. Are|the|immune|cell|that|HIV|attacks| Mature|in|the|thymus Macrophages|-|verified|answersPresent|in|all|organs|and|tissues,|primary|role|is|phagocytosis,|(1)|they| are|required|for|activation|of|T|cells|(both|helper|T|cells|and|cytolytic|T|cells),|(2)|they|are|the|final| mediators|of|DTH,|and|(3)|they|phagocytize|cells|that|have|been|tagged|with|antibodies Dendritic|Cells|-|verified|answersperform|the|same|antigen-presenting|task|as|do|macrophages,|but|do| not|act|as|scavengers Mast|cells|-|verified|answersThese|cells|mediate|immediate|hypersensitivity|reactions,|derived|from| basophils,|concentrated|in|the|skin|and|other|soft|tissues,|release|histamine,|heparin,|and|other| compounds|that|cause|the|symptoms|of|immediate|hypersensitivity Basophils|-|verified|answersThese|cells|mediate|immediate|hypersensitivity|reactions,|circulate|in|the| blood,|release|histamine,|heparin,|and|other|compounds|that|cause|the|symptoms|of|immediate| hypersensitivity

Neutrophils|-|verified|answersphagocytize|bacteria|and|other|foreign|particles,|avidly|devour|cells|that| have|been|tagged|with|antibodies|of|the|immunoglobulin|G|(IgG)|class,|major|contributors|to| inflammation Eosinophils|-|verified|answersattack|and|destroy|foreign|particles|that|have|been|coated|with|antibodies| of|the|IgE|class.|Their|usual|target|is|helminths|(parasitic|worms).|also|contribute|to|tissue|injury|and| inflammation|associated|with|immediate|hypersensitivity|reactions. Antibodies|-|verified|answersare|a|family|of|structurally|related|glycoproteins|that|mediate|humoral| immunity.|The|most|characteristic|feature|is|their|ability|to|recognize|and|bind|with|specific|antigens. Immunoglobulins|and|globulins.|-|verified|answersAlternative|names|for|antibodies|are B|lymphocytes|-|verified|answersall|antibodies|are|produced|by IgA|-|verified|answerslocated|in|mucous|membranes|of|the|GI|tract|and|lungs|and|in|many|secretions,| serve|as|the|first|line|of|defense|against|microbes|entering|the|body|via|these|routes,|transferred|to| infants|via|breastmilk|(not|absorbed|in|the|GI|tract,|but|does|protect|the|infant|from|microbes|in|the|GI| tract) IgD|-|verified|answersfound|only|on|the|surface|of|mature|B|cells|where|it|serves|as|a|receptor|for| antigen|recognition|(along|with|IgM) IgE|-|verified|answersbind|to|the|surface|of|mast|cells,|stimulating|the|release|of|histamine,|heparin,|and| other|mediators|from|the|mast|cell|causing|symptoms|of|allergy|(hives,|hay|fever),|bind|to|parasitic| worms,|eosinophils|bind|to|the|ig,|releasing|compounds|that|lyse|the|worm IgG|-|verified|answersProduced|in|copious|amounts|in|response|to|antigenic|stimulation,|major|antibody| in|blood,|promote|target-cell|lysis,|binds|target|cells|enhancing|phagocytosis,|transferred|across|the| placenta|to|fetal|circulation|providing|neonatal|immunity IgM|-|verified|answersfirst|class|of|antibody|produced|in|response|to|an|antigen,|promotes|target|cell| lysis,|present|on|the|surface|of|mature|B|cells|where|it|serves|as|a|receptor|for|antigen|recognition|along| with|IgD IgM|-|verified|answersif|these|are|high,|it|signifies|an|acute|infection Antigens|-|verified|answersare|molecules|that|induce|specific|immune|responses|and,|as|a|result,| become|the|targets|of|those|responses.|may|trigger|production|of|antibodies,|cytotoxic|T|cells,|or|both— all|of|which|can|then|attack|it epitopes|or|antigenic|determinants|-|verified|answersBecause|antigens|are|large,|antibodies|recognize| and|bind|selected|small|portions|of|the|antigen,|referred|to|as hapten,|carrier|-|verified|answersIn|research|and|in|clinical|practice,|we|may|want|to|generate|antibodies| to|molecules|that|are|too|small|to|induce|an|immune|response.|To|overcome|this|obstacle,|we|can|link| the|small|molecule|to|a|larger|molecule,|usually|a|protein.|When|this|is|done,|the|small|molecule|is| referred|to|as|a|________,|and|the|large|molecule|is|referred|to|as|a|______.|At|least|some|of|the| resultant|antibodies|will|be|selective.

•Anaphylactic|reaction|to|gelatin,|eggs|or|neomycin MMR|-|verified|answerschildren|with|allergies|to|eggs|other|than|anaphylaxis|should|still|be|receive|this| vaccine MMR|-|verified|answersvaccine|can|have|several|adverse|effects,|including|fever|up|to|103°F.|This|is|not| considered|a|serious|effect. DTaP|-|verified|answersUsed|for|routine|vaccination|against|diphtheria,|tetanus,|and|pertussis|(children) DT|-|verified|answersVaccine|used|instead|of|DTaP|for|children|younger|than| 7 |years|who|should|not|get| pertussis|vaccine Tdap|-|verified|answersUsed|as|a|booster|in|adolescents|and|adults|to|protect|against|all|three|diseases| (diphtheria,|tetanus,|pertussis),|currently|recommended|for|anyone|age|11-18. Td|-|verified|answersUsed|as|a|booster|for|adolescents|and|adults|to|protect|against|tetanus|and| diphtheria,|but|not|pertussis,|given|every| 10 |years|after|the|first|booster Diphtheria|and|Tetanus|-|verified|answersProtection|begins|after|the|third|dose|and|lasts|for| 10 |years Pertussis|-|verified|answersProtection|begins|after|the|third|dose,|but|only|for| 4 |to| 6 |years|for|this| component DTaP|-|verified|answersvaccine|with|mild|to|moderate|adverse|reactions|of|Local|reactions,|fever,| fretfulness,|drowsiness,|anorexia,|persistent|crying DTaP|-|verified|answersvaccine|with|severe|adverse|reactions|of|Acute|encephalopathy,|convulsions,| shock-like|state DTaP|-|verified|answersUse|caution|if|administering|this|vaccine|in|these|scenarios| •A|shock|like|state •Fever|(105°F|or|higher)|occurring|within| 48 |hours|of|vaccination|and|not|attributable|to|another| identifiable|cause •Persistent,|inconsolable|crying|lasting| 3 |or|more|hours|and|occurring|within| 48 |hours|of|vaccination •Seizures|(with|or|without|fever)|occurring|within| 3 |days|of|vaccination DTaP|-|verified|answersvaccine|contraindicated|with|•Anaphylactic|reaction •Encephalopathy Poliovirus|-|verified|answersIPV,|IPOL|are|preparations|of|this|vaccine Poliovirus|Vaccine|(IPV,|IPOL)|-|verified|answersVaccine|with|local|soreness|as|a|mild|adverse|effect|and| no|severe|adverse|effects Poliovirus|-|verified|answersUse|precaution|when|administering|this|vaccine|to|someone|with|an|allergy| to|streptomycin,|neomycin,|or|bacitracin|due|to|trace|amounts|in|the|vaccine

Hib|vaccine|-|verified|answersvaccine|prepared|by|conjugating|PRP|with|either|a|tetanus|toxoid|or|OMP| to|enhance|antigenicity OMP|-|verified|answersHib|vaccines|made|with|this|elicit|a|stronger|response OMP|-|verified|answersPedvaxHIB|and|Comvaxa|are|hib|vaccines|made|with Tetanus|toxoid|-|verified|answersActHIB|and|Hiberix|are|hib|vaccines|made|with PedVaxHib|(OMP)|-|verified|answersHib|vaccine|in|which|protection|begins|a|week|after|the|first|dose ACTHib|(tetanus|toxoid)|-|verified|answersHib|vaccine|in|which|protection|begins|a|week|after|the|fourth| dose Hib|Vaccine|(haemophilus|influenzae|type|B)|-|verified|answersvaccine|with|mild|adverse|effects|of|Local| reactions,|fever,|crying,|diarrhea,|vomiting,|and|no|severe|adverse|effects Varicella|Vaccine|-|verified|answerschildren|receiving|this|vaccine|should|Avoid|aspirin|for| 6 |weeks|due| to|Reye|syndrome Live|-|verified|answersThe|varicella|vaccine|is|a|______|virus Varicella|Vaccine|-|verified|answersAvoid|close|contact|with|susceptible|high-risk|individuals|after| receiving|this|vaccine (Neonates,|pregnant|women,|immunocompromised|people) Varivax|-|verified|answersvaccine|that|contains|only|varicella ProQuad|-|verified|answersVaccine|that|contains|varicella|plus|MMR Varicella|Vaccine|-|verified|answersAvoid|this|vaccine|with| •Pregnancy •Cancers|such|as|leukemia|and|lymphoma •Hypersensitivity|to|neomycin|or|gelatin •Immunocompromised|or|taking|immunosuppressants Varicella|Vaccine|-|verified|answersVaccine|with|mild|adverse|effects|of|Local|reactions,|fever,|mild| varicella-like|rash|(local|or|generalized)|and|no|severe|adverse|effects IPV,|MMR|and|varicella.|-|verified|answersPersons|with|an|anaphylactic|reaction|to|neomycin|should| avoid|Persons|with|an|anaphylactic|reaction|to|neomycin|should|avoid|these|vaccines varicella|and|MMR|-|verified|answersPersons|with|an|anaphylactic|reaction|to|gelatin|should|avoid|these| vaccines MMR|-|verified|answersvaccine|with|mild|adverse|effects|of|Local|reactions;|rash;|fever;|swollen|glands| in|cheeks|and|neck|and|under|the|jaw;|pain,|stiffness,|and|swelling|in|joints Engerix-B|-|verified|answersHepatitis|B|vaccine|for|adults

•All|healthy|children|between|their|second|and|fifth|birthdays|who|have|not|completed|the|series •All|children|between|their|second|and|fifth|birthdays|who|have|conditions|that|put|them|at|high|risk|for| this|disease. Pneumococcal|Vaccine|-|verified|answersVaccine|recommended|for|children|with|sickle|cell|anemia,| injury|to|the|spleen,|cochlear|implants,|chronic|heart|or|lung|disease,|or|immunosuppression|of|any| cause|(e.g.,|diabetes,|cancer,|liver|disease,|HIV|infection,|use|of|immunosuppressive|drugs) Meningococcal|vaccine|-|verified|answersVaccine|recommended|for| •Aged| 11 |to| 12 |years|and|a|booster|at| 16 |years •College|freshmen|living|in|dormitories •U.S.|military|recruits •Microbiologists •Anyone|traveling|to|a|part|of|the|world|where|meningococcal|disease|is|common •Injured|spleen|or|whose|spleen|has|been|removed •Immune|disorder|known|as|terminal|complement|component|deficiency •Exposed|to|meningitis|during|an|outbreak •Persons|with|persistent|complement|component|deficiency,|anatomic|or|functional|asplenia,|and| certain|other|risk|factors Meningococcal|Vaccine|-|verified|answersVaccine|with|Mild|adverse|effects|of|Local|pain,|headache,| fatigue,|local|redness,|swelling|and|induration No|severe|adverse|effects Flumist|Intranasal|-|verified|answersLive|influenza|vaccine Influenza|vaccine|-|verified|answersvaccine|recommended|annually|for|anyone| 6 |months|or|older Influenza|Vaccine|-|verified|answers•High|risk|should|receive|the|inactivated|vaccine •<5|years|old •Pregnant|women •>65|years|or|older •Morbidly|obese •Nursing|home •Native|Americans/|Alaskan|Americans •Immunocompromised

•Chronic|diseases|such|as|diabetes,|lung|disease,|etc. Influenza|Vaccine|-|verified|answersVaccine|with|adverse|effects: •Mild:|Fever,|runny|nose,|headache,|cough,|loss|of|appetite •Severe:|Very|small|risk|of|Guillain-Barre'|syndrome Influenza|Vaccine|-|verified|answersVaccine|with|contraindications| •Acute|febrile|illness|-|wait|till|symptoms|resolve|to|vaccinate •Pregnant|women|should|not|receive|live|vaccine -possibly|severe|egg|allergy|per|FDA|(CDC|disagrees) Rotavirus|vaccine|-|verified|answersVaccine •Live,|attenuated|virus •Administered|orally Rotavirus|Vaccine|-|verified|answersVaccine|with|adverse|effects: •Mild:|Diarrhea,|vomiting,|ear|infection,|runny|nose,|sore|throat •Severe:|Intussusception|(rare) Rotavirus|Vaccine|-|verified|answersVaccine|recommended|for|all|infants|beginning|at| 8 |weeks|of|age Precaution|with| •Immunocompromised|infants •Currently|ill|with|moderate|to|severe|diarrhea|or|vomiting Rotavirus|vaccine|-|verified|answersVaccine|contraindicated|with| •Uncorrected|congenital|malformation|of|the|GI|tract;|Severe|Combined|Immunodeficiency HPV|Vaccine|-|verified|answersvaccine|recommended|to|•Prevent|cancers,|precancerous|lesions,|and| genital|warts|in|females|and|males|aged|9-45|years|of|age HPV|Vaccine|-|verified|answersVaccine|with|adverse|reactions|of|•Mild:|Local|reactions,|pain,|erythema,| swelling,|and|itching,|and|fainting •Severe:|None MMR,|Varicella,|Flumist|(intranasal),|Rotavirus|-|verified|answersVaccinations|that|are|live PCV,|Meningococcal|-|verified|answersrecommended|vaccines|for|injured|spleen HPV|-|verified|answersHave|patient|lay|down|with|this|vaccine|due|to|risk|of|fainting Histamine|(H1|receptors)|-|verified|answersPlays|a|major|role|in|mild|allergy|symptoms,|Rhinitis,|itching,| localized|edema

Aspirin|-|verified|answers•Pregnancy:|Poses|risk|for|premature|closure|of|the|ductus|arteriosus|and| increased|risk|for|anemia|and|postpartum|hemorrhage.|Do|not|give|full|dose|in|pregnancy|starting|at| 30 | weeks|gestation|(low-dose|is|ok);|Do|give|full|dose|to|a|breastfeeding|mom|of|infant|with|viral|infection •Monitor|for|salicylism ringing|in|the|ears|-|verified|answersmajor|sign|of|salicylism ibuprofen|(advil)|-|verified|answers•Inhibits|cyclooxygenase,|reducing|prostaglandin|and|thromboxane| synthesis|(reversible) Ibuprofen,|Celebrex|-|verified|answers•BBW:|CV|Thrombotic|Event|and|GI|Bleeding,|Ulceration|and| Perforation Ibuprofen|-|verified|answersNSAID|that|may|delay|ovulation,|caution|with|females|trying|to|conceive Ibuprofen|-|verified|answers•Monitoring:|Cr|if|severe|renal|dz;|CBC,|chemistry|profile|if|long-term|tx;|BP;| s/sx|hepatic|impairment|in|peds|pts|if|dose|>30|mg/kg/day|or|abnormal|LFTs|w/|prior|NSAID|tx •Take|with|food|or|milk|to|lessen|stomach|upset. •"can|increase|your|risk|of|fatal|heart|attack|or|stroke.|Do|not|use|this|medicine|just|before|or|after|heart| bypass|surgery|(coronary|artery|bypass|graft,|or|CABG).|may|also|cause|stomach|or|intestinal|bleeding,| which|can|be|fatal." Ibuprofen|-|verified|answersNSAID|of|choice|while|breastfeeding Ibuprofen,|Celebrex|-|verified|answersNSAIDs|to|avoid|at| 30 |weeks|gestation,|weigh|risk/benefits,|may| use|while|breastfeeding Celebrex|-|verified|answers•Can|increase|the|risk|of|fatal|heart|attack|or|stroke;|Do|not|take|after|or| before|a|CABG;|May|cause|stomach|or|intestinal|bleeding;|Do|not|take|if|you|have|a|sulfa|allergy •Monitoring:|Cr|at|baseline,|then|if|elderly,|renal|or|hepatic|impairment,|CHF,|dehydration,|or| hypovolemia|cont.|periodically;|BP|during|tx|start,|then|periodically;|CBC,|chemistry|profile|if|long-term| tx;|coagulation|tests|if|systemic|onset|JIA Aspirin|-|verified|answersdo|not|take|if|CrCl|is|less|than| 10 Ibuprofen,|Celebrex|-|verified|answersdo|not|take|if|CrCl|is|less|than| 30 Acetaminophen|-|verified|answers•Analgesic|mechanism|of|action|unknown;|antipyretic|effect|via|direct| action|on|the|hypothalamic|heat-regulating|center;|decreases|prostaglandin|synthesis|in|the|CNS| reducing|fever|and|pain Acetaminophen|-|verified|answersCan|use|during|pregnancy|and|breastfeeding|for|pain,|fever Acetaminophen|-|verified|answersBBW:|Hepatotoxicity|and|Medication|Error|Risk|for|IV|use Acetaminpophen|-|verified|answers•Infant|and|children|dosing:|10-15|mg/kg/dose|PO|q4-6h|prn|(Be| sure|to|use|Infants'|and|Childrens') Acetaminophen|-|verified|answers•Antidote|for|overdose:|Acetylcysteine

Acetaminophen|-|verified|answers•Monitoring:|Cr|at|baseline;|LFTs|if|high-dose|or|long-term|tx,|esp.|if| pre-existing|hepatic|disease •Severe|liver|damage|may|occur|if|patient|consumes| 3 |or|more|alcoholic|drinks|every|day Acetaminophen|-|verified|answersNo|antiinflammatory|and|antirheumatic|actions,|does|not|suppress| platelet|aggregation,|does|not|cause|gastric|ulceration,|and|does|not|decrease|renal|blood|flow|or|cause| renal|impairment.|However,|overdose|can|cause|severe|liver|injury. Glucocorticoid|-|verified|answerselevate|blood|glucose,|elevate|BP,|decrease|immune|system,|reduce| muscle|mass,|decrease|protein|matrix|of|bone,|cause|thinning|of|skin,|potbelly,|moon|face,|buffalo|hump, Glucocorticoids,|epinephrine|-|verified|answersadrenal|glands|should|secrete|more|of|this|in|times|of| stress Glucocorticoids|-|verified|answers•Insufficient|release|during|stress:|Hypotension|and|hypoglycemia| occur •Very|severe|stress:|insufficiency|can|result|in|circulatory|failure|and|death Glucocorticoid|-|verified|answersmay|need|to|increase|dosage|in|stressful|situations|due|to|an|increase| in|demand|(such|as|in|hospitalized|patients) Glucocorticoid|-|verified|answerscan|exert|actions|similar|to|aldosterone|(fluid|and|sodium|retention,| potassium|excretion)|causing|edema,|hypernatremia,|hypokalemia|(most|drugs|utilized|in|this|class|have| very|low|activity|such|as|this) Glucocorticoid|Withdrawal/Weening|-|verified|answersTo|allow|time|for|recovery|of|adrenal|function,| withdrawal|should|be|done|slowly,|schedule|determined|by|the|degree|of|adrenal|suppression.|Ex:|(1)| taper|the|dosage|to|a|physiologic|range|over| 7 |days;|(2)|switch|from|multiple|daily|doses|to|single|doses| administered|each|morning;|(3)|taper|the|dosage|to|50%|of|physiologic|values|over|the|next|month;|and| (4)|monitor|for|production|of|endogenous|cortisol|and,|when|basal|levels|have|returned|to|normal,| cease|routine|(but|be|prepared|to|give|supplemental|doses|at|times|of|stress). 2 |to| 3 |weeks|-|verified|answersAs|a|rule,|tapering|is|unnecessary|when|oral|glucocorticoids|have|been| used|for|less|than low|and|slow|-|verified|answersif|there|is|no|immediate|threat,|start|glucocorticoids... Start|high|and|decrease|as|possible|-|verified|answersIf|there|is|an|immediate|threat,|start| glucocorticoids.... Prolonged,|high|dose|glucocorticoids|-|verified|answersis|used|only|if|disorder|is|life-threatening|or|has| potential|to|cause|permanent|disability Glucocorticoids|-|verified|answershave|much|greater|anti-inflammatory|effects|than|NSAIDS Prednisone|-|verified|answers•May|use|while|breastfeeding,|consider|holding|breastfeeding|x4h|after| dose|if|prolonged|high-dose|use

Tamoxifen|(Nolvadex)|-|verified|answers•Common:|hot|flashes,|fluid|retention,|vaginal|discharge,|N,|V,| menstrual|irregularities •Ocular|changes:|cataracts,|corneal|deposits Tamoxifen|(Nolvadex)|-|verified|answers•Inhibitors|of|CYP2D6|can|prevent|activation|of|tamoxifen •Grapefruit|juice|decreases|metabolism Anastrozole|(Arimidex)|-|verified|answers•ER|positive|breast|cancer|in|postmenopausal|women Anastrozole|(Arimidex)|-|verified|answers•Potent|and|selective|nonsteroidal|aromatase|inhibitor •Inhibiting|aromatase|stops|conversion|of|androstenedione|to|estrone|and|testosterone|to|estradiolà| Block|the|production|of|estrogen|from|androgenic|precursors •Do|not|block|estrogen|produced|by|ovaries,|therefore|is|not|helpful|in|premenopausal|women (•block|estrogen|biosynthesis) Arimidex|(anastrozole)|-|verified|answers•1|mg|by|mouth|daily •5-10|years|of|endocrine|therapy Arimidex|-|verified|answersContraindications: •Pregnancy •Caution|in|hepatic|impairment Aromatase|inhibitors|(arimidex)|-|verified|answersare|more|effective |pose|no|risk|for|endometrial|cancer| only|rarely|cause|thromboembolism.| can|increase|the|risk|for|fractures|and|have|been|associated|with|moderate|to|severe|myalgias. Arimidex|(anastrozole)|-|verified|answers•MS|pain •Asthenia •HA •Menopausal|symptoms|(hot|flashes,|vaginal|dryness) •GI|(anorexia,|V,|D,|C, •Dyspnea •Peripheral|edema •Vaginal|hemorrhage •HTN

•Osteoporosis|and|fracture|(due|to|estrogen|depletion) Trastuzumab|(Herceptin)|-|verified|answers•Monoclonal|antibody|that|binds|to|the|human|epidermal| growth|factor|receptor|(HER-2) •Stops|proliferation|of|cells|which|overexpress|HER-2|protein. Herceptin|(trastuzumab)|-|verified|answersUse: •HER2|positive|adjuvant|breast|cancer •HER2|positive|metastatic|breast|cancer •Gastric|cancer •Alone|or|in|combination|with|chemotherapy|drugs Herceptin|-|verified|answersContraindications: •Pregnancy:|contraception|until| 7 |months|after|last|dose Herceptin|-|verified|answersDosing|and|Administration: •Loading|dose •Maintenance|dose •Every| 3 |weeks|for| 1 |year •IV|dosing Herceptin|-|verified|answersBBW: •Cardiomyopathy •Infusion|reactions •Pulmonary|toxicity •Pregnancy|should|be|avoided Herceptin|-|verified|answersAdverse|Effects: •Cardiotoxicity •Flu-like|symptoms|(chills,|fever,|pain,|weakness,|N,|V,|HA) Herceptin|-|verified|answersteach|patient|about|adverse|effects,|BBW,|and|need|for|MUGA|and|cardiac| assessments|due|to|the|cardiotoxicity-|teach|signs|of|heart|failure|(fluid|retention,|edema,|shortness|of| breath) Leuprolide(Lupron)|-|verified|answers•Suppresses|androgen|production|in|testes •Lowers|testosterone|levels|(chemical|castration) •It|does|not|decrease|testosterone|made|by|adrenal|glands|or|the|prostate|cancer|itself.

Group|A|-|verified|answersCOPD|with|low|symptom,|low|risk Group|B|-|verified|answersCOPD|with|high|symptom,|low|risk Group|C|-|verified|answersCOPD|with|low|symptom,|high|risk Group|D|-|verified|answersCOPD|with|high|symptom,|high|risk Bronchdilator|-|verified|answersCOPD|group|A|initial|treatment LABA|and|LAMA|-|verified|answersgroup|B|initial|treatment|COPD LABA|and|LAMA|and|possibly|ICS|-|verified|answersCOPD|initial|treatment| •If|≥| 2 |moderate|exacerbations|or|≥| 1 |leading|to|hospitalization •Consider|if|eosinophil|count|is|≥| 300 |cells/microliter Asthma|treatment|-|verified|answerstreatment|is|a|stepwise|approach|based|on|age,|severity,|and| classification Theophylline|-|verified|answersnot|recommended|for|COPD|unless|other|bronchodilators|are|too| expensive|or|unavailable Asthma|-|verified|answersICS|is|the|most|effective|long-term|control ICS|-|verified|answersmay|slow|a|child's|growth,|but|so|does|uncontrolled|asthma LABA|-|verified|answersnot|used|as|a|monotherapy|for|asthma LABA|-|verified|answersused|as|an|add|on|for|ICS|in|asthma 5 |minutes|before|-|verified|answersinhale|SABA|___|glucocorticoid|to|enhance|the|glucocorticoid Beclomethasone|(QVAR)|glucocorticoid|-|verified|answersnot|prn,|must|take|regularly,|inhaled|is|safer| and|more|effective,|most|effective|treatment|for|airway|inflammation|(asthma),|rinse|mouth|to|decrease| candidiasis Montelukast|-|verified|answersnot|a|prn|medication,|primarily|used|with|ICS,|possible|mood|changes Cromolyn|-|verified|answersnot|a|prn|medication,|not|the|preferred|drug,|used|if|glucocorticoids|cause| an|issue Roflumilast|(Daliresp)|-|verified|answersnot|a|first|line|drug,|used|for|frequent|exacerbations|with|COPD,| use|caution|in|patients|with|depression Bronchodilators|-|verified|answersmonotherapy|for|asthma|is|only|appropriate|when|asthma|is|very|mild| with|infrequent|attacks,|provide|a|symptomatic|relief,|do|not|help|with|underlying|inflammation Systemic|anticholinergics|-|verified|answersbronchodilator|on|the|BEERS|list,|try|to|used|inhaled|instead Inhaled|anticholinergics|-|verified|answersamong|the|safer|bronchodilator|for|preg|women LABA|-|verified|answerspreferred|over|SABA|for|COPD

1 |minute|apart|-|verified|answersif|a|dose|requires|two|inhalations,|administer|them..... Albuterol|(ProAir)|-|verified|answersSABA|(bronchodilator) Albuterol|(proair)|-|verified|answersSABA,|use|caution|with|tachydysrhythmias,|can|cause|palpations,| tachy,|angina,|headache,|cough Albuterol|(proair),|SABAs|-|verified|answersused|prn|for|acute|attack,|used|to|prevent|exercise|induced Theophylline|(methylxanthine|bronchodilator)|-|verified|answershas|many|drug|reactions|including| caffeine,|tobacco,|marijuana,|phenobarb,|phenytoin,|cimetidine,|fluroquinolones,|etc. Theophylline|-|verified|answersbronchodilator,|watch|for|toxicity,|N,|V,|D,|insomnia,|restlessness,|severe| toxicity|can|cause|convulsions|and|dysrhythmia Atrovent|(Ipratropium)|-|verified|answersshort|acting|anticholinergic,|use|sugar|free|hard|candy|for|dry| mouth Spiriva|(tiotropium)|-|verified|answersused|for|COPD,|not|asthma,|long|acting|anticholinergic,|more| effective|than|Atrovent,|sugar|free|hard|candy|for|dry|mouth Fluticasone|(flonase)|-|verified|answersglucocorticoid,|most|effective|for|rhinitis,|intranasal Antihistamines|(claritin|Zyrtec)|-|verified|answersrelieve|rhinorrhea,|reduce|sneezing,|reduce|nasal| itching Pseudoephedrine|(Sudafed)|-|verified|answersonly|helps|decrease|nasal|congestion common|cold|-|verified|answersrinorrhea,|nasal|congestion,|cough,|sneeze,|sore|throat,|headache,| hoarse,|malaise,|myalgia,|fever|common|in|kids|with|this,|no|cure,|symptom|management Children|younger|than| 4 |to| 6 |-|verified|answersavoid|over|the|counter|cold|remedies|in children|-|verified|answersavoid|antihistamines|in|this|population|due|to|sedation Afrin|(oxymetazoline)|-|verified|answersintranasal|decongestant,|vasoconstriction|of|swollen| membranes,|monitor|for|rebound|congestion,|used|for|short|periods|(3-5|days) Pseudoephedrine|(sudafed)|-|verified|answersoral|decongestant,|contraindicated|with|hypertension!!,| monitor|for|CNS|stimulation,|monitored|medication Codeine|-|verified|answersmost|effective|opioid|antitussive,|can|suppress|respirations,|scheduled| medication,|CI|in|Ultra-rapid|CYP2D6|metabolizers,|respiratory|depression,|children|less|than| 12 |years|of| age,|post-tonsillectomy|and|adenoidectomy,|asthma,|GI|obstruction Dextromethorphan|-|verified|answersmost|effective|nonopioid|antitussive,|can|have|some|opioid|affects