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NURS 1140 Pharm Final Exam Questions
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Which medication class can be used in combination with antimicrobial agents to eradicate a Helicobacter pylori infection? A. Antacids B. Prokinetic agents C. Proton pump inhibitors D. Gastrointestinal prostaglandins - โโC. Proton pump inhibitors Which medication may cause breast soreness and gynecomastia? A. Cimetidine (Tagamet) B. Misoprostol (Cytotec) C. Lansoprazole (Prevacid) D. Metoclopramide (Reglan) - โโA. Cimetidine (Tagamet) Which medication when given to a patient taking a proton pump inhibitor may cause nystagmus? A. Clopidogrel (Plavix) B. Phenytoin (Dilantin) C. Sucralfate (Carafate) D. Warfarin (Coumadin) - โโB. Phenytoin (Dilantin) Which laboratory test does the nurse review before a patient takes a magnesium-based OTC antacid for heartburn? A. Gastric pH B. Electrolytes C. Liver function
D. Renal function - โโD. Renal function Which medication could be beneficial for the treatment of intermittent heartburn? A. Misoprostol B. Esomeprazole C. Metoclopramide D. Sucralfate - โโB. Esomeprazole Which type of ulcer has misoprostol been known to reduce? A. Stress B. Esophageal C. Helicobacter pylori D. Nonsteroidal antiinflammatory drug (NSAID)-induced - โโD. Nonsteroidal antiinflammatory drug (NSAID)-induced Which antiulcer medications act by antagonizing histamine-2 (H2) receptors? Select all that apply. A. Nizatidine (Axid) B. Famotidine (Pepcid) C. Misoprostol (Cytotec) D. Cimetidine (Tagamet) E. Esomeprazole (Nexium) - โโA, B, D Which medications reduce gastric ulcers by inhibiting hydrogen ion pumps? Select all that apply. A. Amoxicillin (Amoxil) B. Cimetidine (Tagamet) C. Misoprostol (Cytotec) D. Pantoprazole (Protonix) E. Dexlansoprazole (Dexilant) - โโD, E
A patient asks the nurse if there is a medication to help decrease the risk of a peptic ulcer due to long- term nonsteroidal antiinflammatory drug (NSAID) use. Which drug does the nurse identify as a possibility? A. Cimetidine (Tagamet HB) B. Misoprostol (Cytotec) C. Pantoprazole (Protonix) D. Metoclopramide (Reglan) - โโB. Misoprostol (Cytotec) Which common adverse effect is associated with famotidine? A. Dizziness B. Anorexia C. Jaundice D. Mild gynecomastia - โโA. Dizziness Which medication is used to treat gastric reflux esophagitis? A. Sucralfate (Carafate) B. Lansoprazole (Prevacid) C. Metoclopramide (Reglan) D. Dexlansoprazole (Dexilant) - โโC. Metoclopramide (Reglan) Which basic principle does the nurse consider when scheduling the administration of drugs used to treat patients with GERD or peptic ulcer disease (PUD)? A. These drugs must be given with meals or snacks. B. Individualized scheduling is required to avoid drug interactions. C. These drugs are taken only in the presence of active symptomatology. D. Significant fluid and electrolyte imbalances are associated with these drugs. - โโB. Individualized scheduling is required to avoid drug interactions A patient is diagnosed with diabetic gastroparesis. Which medication does the nurse recognize as appropriate in treating a patient with diabetic gastroparesis?
A. Omeprazole B. Dexlansoprazole C. Metoclopramide D. Famotidine - โโC. Metoclopramide Which statement best describes the action of phenothiazines? A. They are dopamine antagonists that inhibit dopamine receptors. B. They are serotonin (5-HT3) antagonists that block receptors known to induce nausea and vomiting. C. They are anticholinergic agents used to counterbalance the excessive amounts of acetylcholine present. D. They are potent, selective neurokinin-1 receptor antagonists that block the effects of substance P in the central nervous system. - โโA. They are dopamine antagonists that inhibit dopamine receptors. Which drug is a dopamine antagonist? A. Aprepitant B. Meclizine C. Haloperidol D. Ondansetron - โโC. Haloperidol Which action describes the function of the chemoreceptor trigger zone (CTZ)? Select all that apply. A. Initiating vomiting B. Coordinating the vomiting reflex C. Receiving stimuli from the cerebral cortex D. Responding to stimuli originating in the inner ear E. Evaluating the spinal fluid for potentially toxic substances - โโC, E What are the priority assessments involved in the basic assessment of nausea and vomiting? Select all that apply. A. Obtain baseline vital signs. B. Assess and record signs of hydration.
Which drug causes profound hypotension and loss of consciousness when used with serotonin antagonists? A. Meclizine (Antivert) B. Aprepitant (Emend) C. Dronabinol (Marinol) D. Apomorphine (Apokyn) - โโD. Apomorphine (Apokyn) Which condition may be a cause of nausea and vomiting during pregnancy? A. Obesity B. Diabetes C. Thyroid disease D. Gallbladder disease - โโA. Obesity Which statement is true about cannabinoids? A. They are more effective than metoclopramide. B. They serve as antiemetics only in patients receiving chemotherapy. C. They are less effective in younger patients who are refractory to other antiemetic agents. D. They are more effective than prochlorperazine in patients receiving moderately emetogenic chemotherapy. - โโB. They serve as antiemetics only in patients receiving chemotherapy. Which drug has a high potential for emesis when given intravenously? A. Paclitaxel (Taxol) B. Cisplatin (Platinol-AQ) C. Carboplatin (Paraplatin) D. Daunorubicin (Cerbidine) - โโB. Cisplatin (Platinol-AQ) Which type of vomiting is best treated by the anticholinergic properties of antihistamine drugs? A. Delayed emesis
B. Motion sickness C. Morning sickness D. Anticipatory nausea and vomiting - โโB. Motion sickness Which drug is a serotonin antagonist? A. Granisetron (Kytril) B. Meclizine C. Promethazine (Phenergan) D. Trimethobenzamide (Tigan) - โโA. Granisetron (Kytril) Arrange the sequence of events occurring during vomiting chronologically. - โโ1. Stimulation of the vomiting center (VC)
- Increase in abdominal pressure
- Raising of the soft palate and closure of the epiglottis
- Contraction of the pyloric sphincter and relaxation of the cardiac sphincter
- Increased flow of saliva to aid in expulsion of vomitus Which type of vomiting may a patient with hyperemesis gravidarum experience? A. Motion sickness B. Morning sickness C. Psychogenic vomiting D. Postoperative vomiting - โโB. Morning sickness Which mechanism of emesis would be anticipated in a patient who frequently travels by aircraft? A. Stimulation of the labyrinth B. Self-induced response to the situation C. Detecting potentially toxic substances in the blood D. Conditioned response triggered by the sight or smell - โโA. Stimulation of the labyrinth
C. Antiemetics are ineffective in cases of anticipatory vomiting D. Antiemetics are more effective when given before the onset of nausea. - โโD
