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NURS 660 EXAM 2: Bipolar Disorder Medications and Treatment, Exams of Nursing

Bellarmine University (BU)Nursing

A comprehensive overview of medications used in the treatment of bipolar disorder, including their mechanisms of action, side effects, and interactions. It also covers key concepts related to bipolar disorder management, such as rapid cycling, lithium toxicity, and serotonin syndrome. Presented in a question-and-answer format, making it a valuable resource for students and professionals seeking to deepen their understanding of this complex mental health condition.

Typology: Exams

2024/2025

Available from 02/28/2025

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NURS 660 EXAM 2 With 100% Correct
Answers 2025/2026
Which medication has the SE of losing hair - Correct Answer-Lithium
The pt is bipolar, and had a partial response to depakote and now is going to be
augmented with an atypical antipsychotic, the effects of atypical antipsychotics in non-
psychotic mania may be due to what - Correct Answer-indirect effect on glutamate
release via 5H2A antagonism
A pt has had some success with his current antidepression medication, has tried many
different antidepressants, so you decide to augment with L-methyl-folate. What is the
hypothesis behind L methyl Folate boosting the therapeutic efficacy of
antidepressants...what is the MOA? - Correct Answer-boosts monamine
neurotransmitter function in bipolar disorder
You have a pt that has been very depressed and has insomnia problems with
concentrations, weight loss and SI. You start them on an AD and his symptoms have
abated, however which of the following symptoms is the most likely to be residual
following the successful tx of other symptoms? - Correct Answer-insomnia
Which class of antidepressant have a lower incidence of sexual SE? What medication is
used in the tx of BP/mania and is used in prophylaxis as well as antidepressant
augmentation? Which medication is this? - Correct Answer-Wellbutrin
What medication is a very potent CYP450 inhibitor and can dangerously elevate
lamotrigine? - Correct Answer-Valproate
Which class of antidepressant has the worst discontinuation syndrome? - Correct
Answer-Cymbalta
You have a female pt complaining of lactating and is not pregnant w/ no children. She
has been taking risperidone. Which medication would you avoid if you were to switch
her to another med?" - Correct Answer-Paliperidone
A pt is on Prozac and it has stopped working. Patient has been on many other
antidepressants and wants to try an MAOI now. How long do you need to stop Prozac
before starting MAOI? - Correct Answer-5-6 weeks
What neurotransmitter are affected by TCAs? - Correct Answer-Serotonin, dopamine,
norepinorphrenie, 5HT
What TCA medication should absolutely not be used in combination with any other
MAOI? - Correct Answer-chlomipramine
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Download NURS 660 EXAM 2: Bipolar Disorder Medications and Treatment and more Exams Nursing in PDF only on Docsity!

NURS 660 EXAM 2 With 100% Correct

Answers 2025/

Which medication has the SE of losing hair - Correct Answer-Lithium The pt is bipolar, and had a partial response to depakote and now is going to be augmented with an atypical antipsychotic, the effects of atypical antipsychotics in non- psychotic mania may be due to what - Correct Answer-indirect effect on glutamate release via 5H2A antagonism A pt has had some success with his current antidepression medication, has tried many different antidepressants, so you decide to augment with L-methyl-folate. What is the hypothesis behind L methyl Folate boosting the therapeutic efficacy of antidepressants...what is the MOA? - Correct Answer-boosts monamine neurotransmitter function in bipolar disorder You have a pt that has been very depressed and has insomnia problems with concentrations, weight loss and SI. You start them on an AD and his symptoms have abated, however which of the following symptoms is the most likely to be residual following the successful tx of other symptoms? - Correct Answer-insomnia Which class of antidepressant have a lower incidence of sexual SE? What medication is used in the tx of BP/mania and is used in prophylaxis as well as antidepressant augmentation? Which medication is this? - Correct Answer-Wellbutrin What medication is a very potent CYP450 inhibitor and can dangerously elevate lamotrigine? - Correct Answer-Valproate Which class of antidepressant has the worst discontinuation syndrome? - Correct Answer-Cymbalta You have a female pt complaining of lactating and is not pregnant w/ no children. She has been taking risperidone. Which medication would you avoid if you were to switch her to another med?" - Correct Answer-Paliperidone A pt is on Prozac and it has stopped working. Patient has been on many other antidepressants and wants to try an MAOI now. How long do you need to stop Prozac before starting MAOI? - Correct Answer- 5 - 6 weeks What neurotransmitter are affected by TCAs? - Correct Answer-Serotonin, dopamine, norepinorphrenie, 5HT What TCA medication should absolutely not be used in combination with any other MAOI? - Correct Answer-chlomipramine

Please know what is the most potent property of trazodone by what neurotransmitter? - Correct Answer-SEDATION; 5H2A Patient prescribed Clomipramine suddenly stops taking medication. What side effects could be shown? - Correct Answer-Cardiovascular, coma, seizure, death What neurotransmitters are effected by tricyclic antidepressants - Correct Answer- increase levels of norepinephrine and serotonin, and block the action of acetylcholine You have a patient that has rapid cycling bipolar disorder. Which combination that should be given together? - Correct Answer-lithium and lurasideon, lamotrigine and quetiapine You have a patient that has rapid cycling bipolar disorder. Which combination that should not be given together? - Correct Answer-carbamazepine lurasidone, valproate and quetiapine What medication is safe to take with MAOI - Correct Answer-Lithium What are the two factors that are most useful for determining if a presenting depressive episode is unipolar or bipolar? - Correct Answer-family history, input from someone close The only atypical approved for bipolar depression - Correct Answer-quetiapine A 28 yr old woman presents with depression. She has been treated with manic episode before however is not taking medication. Whhat meds work the best to tx bipolar depression? - Correct Answer-Lamictal Does clozapine increase TCA A levels? - Correct Answer-true Cigarette smoking decrease TCA levels - Correct Answer-false How many half-lives do you have to wait before you can initiate MAOI inhibitor medication - Correct Answer-5 half lives Which antidepressant and drug class has a higher incident of gaining weight out of all the Antidepressants - Correct Answer-paxil: SSRI Which medication can cause hypothyroidism? - Correct Answer-Lithium Patient comes into the office for smoking cessation education also has a seizure disorder. Which of the following medications WOULD NOT be appropriate - Correct Answer-Wellbutrin

What is lamotrigine's unique therapeutic profile in BP disorder and depression? - Correct Answer-linked to inhibition glutamate release Which medication would you warn clients not to stop abruptly? - Correct Answer-effexor You are going to be prescribing a CYP34A inducer...what medication should you avoid adding into the pt's med profile? - Correct Answer-CYP3A4 substrate Medications with the MOA of reuptake of 5HT - Correct Answer-Paxil, celexa, Zoloft, prozac, fluvoxamine, and lexapro Medications with the MOA of the reuptake of 5HT and norepinephrine - Correct Answer- duloxetine, Effexor What is the MOA of agomelatine? - Correct Answer-Binds to melatonin receptors in the suprachiamatic nucleus and to 5HT2C receptors Agents that block the reuptake of norepinephrine, has what effect on the dopamine in the prefrontal cortex - Correct Answer-increased dopamine in PFC