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Nutraceutical Potential Of ASHWAGANDHA, Study notes of Pharmacognosy

This pdf describes the associated health benefits of Ashwagandha as a nutraceutical preparation.

Typology: Study notes

2021/2022

Available from 06/14/2022

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NUTRACEUTICAL POTENTIAL
OF
ASHWAGANDHA
College- GOA COLLEGE OF PHARMACY
Course- Bachelors of Pharmacy
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NUTRACEUTICAL POTENTIAL

OF

“ASHWAGANDHA”

College- GOA COLLEGE OF PHARMACY

Course- Bachelors of Pharmacy

SYNONYMS:

 Winter cherry, Asgandh, Withania root, Poison gooseberry, Indian ginseng

BIOLOGICAL SOURCE:

 It consists of the dried roots and stem bases of Withania somnifera (Linn.) Dunal.  It should contain not less than 0.02% of total withanolide A and withaferin A on dried basis.  Family – Solanaceae

CHEMICAL CONSTITUENTS:

The main constituents of Ashwagandha are : Alkaloids and steroidal lactones 1) Alkaloids:  Major – Withanine  Others-somniferine, somnine, choline, cuscohygrine, anahydrine, anaferine, tropine, pseudotropine, withananine, somniferinine, 3-α-gloyloxytropane, Isopelletierine.  Two acyl steryl glucosides i.e Sitoindoside VII & Sitoindoside VIII have been isolated from the roots.

Anaferine

2) Steroidal lactones / Withanolides The leaves contain steroidal lactones. They have C28 steroidal nucleus with C9 side chain, having six-membered lactone rings.  Withaferin and withaferin A (obtained from W. somnifera chemotype I)  Withaferin E to M (Obtained from chemotype III)

and pain in the joints and especially in case of morning joint stiffness by preventing bone degeneration

5. For diabetes: Its very good remedy for the person who is suffering from Type 2 diabetes. It may also be effective in increasing the insulin sensitivity as well as lower the complications linked with diabetes. 6. Antioxidant property: Ashwagandha is very rich in antioxidants. These antioxidants are very good in scavenging and neutralizing the free radicals which are generally produced during the process of metabolism. 7. Other health benefits:  For enhancing the blood circulation.  Aphrodisiac properties.  Effective in preventing seizures.  Good in lowering the ocular disease.

The leaf extracts shows activity against Staphylococcus aureus and Ranikhet virus.

MARKETED PEPARATIONS: