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Objectives in microbiology, Assignments of Microbiology

This is chapter 2 objectives in microbiology for BRCC.

Typology: Assignments

2021/2022

Uploaded on 12/05/2023

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Chapter 2: Chapter Specific Learning Outcomes
From Atoms to Macromolecules
1.Define the term atom and describe its parts.
-Atoms are substances that make up matter and are the smallest units of elements
- The atomic nucleus is the center of an atom and in the atomic nucleus there are protons and
neutrons. The protons are a positive charge and the neutrons are a neutral charge. The electrons
are a negative charge and they are located around the nucleus.
2.Determine the atomic mass, atomic number, and chemical symbol of an element using the
periodic table.
- The element Helium has an atomic mass of 4.003, the atomic number is 2 , and the chemical
symbol is He.
3.Describe the difference between an anion and a cation and state how they are formed.
- The difference between an anion and a cation is the overall charge and gained electrons. In
cations the atoms have lost electrons and have an overall positive charge.
4.Discuss what isotopes are and explain how they are important in medicine.
- All elements exist as a mixture of isotopes, which are atoms with the same number of protons
but different numbers of neutrons.
- A field called nuclear medicine has also become increasingly important in modern health care.
This branch of health care uses radiopharmaceuticals, or drugs that contain specific isotope
formulations, to diagnose and treat certain diseases.
5.Define the terms molecule, compound, and isomer.
- A molecule is formed when two or more atoms bond together. An elemental hydrogen
molecule contains two atoms of hydrogen (H2), while a molecule of water contains two
hydrogen atoms and one oxygen atom.
- A compound is a term used to describe molecules that are made of more than one type of
element.
- An isomer are molecules with the same molecular formula but different molecular structures.
7.Differentiate between organic and inorganic compounds.
- Organic compounds are molecules that contain carbon and hydrogen. An inorganic compound
are molecules that lack carbon , even if carbon is present.
- Organic molecules are typically more complex than inorganic molecules, but that doesn’t mean
they are more important to life than inorganic compounds. Both organic and inorganic
molecules are necessary for life.
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Chapter 2: Chapter Specific Learning Outcomes

From Atoms to Macromolecules

  1. Define the term atom and describe its parts.
  • Atoms are substances that make up matter and are the smallest units of elements
  • The atomic nucleus is the center of an atom and in the atomic nucleus there are protons and neutrons. The protons are a positive charge and the neutrons are a neutral charge. The electrons are a negative charge and they are located around the nucleus.
  1. Determine the atomic mass, atomic number, and chemical symbol of an element using the periodic table. - The element Helium has an atomic mass of 4.003, the atomic number is 2 , and the chemical symbol is He. 3 .Describe the difference between an anion and a cation and state how they are formed.
  • The difference between an anion and a cation is the overall charge and gained electrons. In cations the atoms have lost electrons and have an overall positive charge.
  1. Discuss what isotopes are and explain how they are important in medicine.
  • All elements exist as a mixture of isotopes, which are atoms with the same number of protons but different numbers of neutrons.
  • A field called nuclear medicine has also become increasingly important in modern health care. This branch of health care uses radiopharmaceuticals , or drugs that contain specific isotope formulations, to diagnose and treat certain diseases.
  1. Define the terms molecule, compound, and isomer. - A molecule is formed when two or more atoms bond together. An elemental hydrogen molecule contains two atoms of hydrogen (H 2 ), while a molecule of water contains two hydrogen atoms and one oxygen atom.
  • A compound is a term used to describe molecules that are made of more than one type of element.
  • An isomer are molecules with the same molecular formula but different molecular structures.
  1. Differentiate between organic and inorganic compounds. - Organic compounds are molecules that contain carbon and hydrogen. An inorganic compound are molecules that lack carbon , even if carbon is present.
  • Organic molecules are typically more complex than inorganic molecules, but that doesn’t mean they are more important to life than inorganic compounds. Both organic and inorganic molecules are necessary for life.
  1. Compare acids and bases and discuss their effects on pH. - Acids contribute hydrogen ions (H+) to an aqueous solution.
  • Bases release hydroxide ions (OH−) in an aqueous solution.
  • pH is calculated based on the concentration of H+^ ions: pH = −log 10 [H+]. The higher the concentration of H+, the lower the pH.
  • The balance of H+^ and OH−^ ions is what determines the overall acidity or basicity of a solution, also called the pH.
  • Basic, or alkaline, solutions have a higher concentration of OH−^ compared to H+^ ions and exhibit a pH greater than 7.
  • Acidic solutions have a higher concentration of H+^ than OH−^ ions and have a pH less than 7.
  • Chemical Bonds
  1. Compare and contrast ionic and covalent bonds. - An ionic bond is the electrostatic force of attraction that exists between oppositely charged ions (between cations and anions). Ionic bonds form when electrons are transferred from one atom to another to make ions.
  • A covalent bond is the electrostatic force of attraction between atoms that share one or more pairs of electrons. 14. Discuss what polar covalent bonding is and how it sets the stage for hydrogen bonding. - A polar covalent bond is a covalent bond in which electrons are not equally shared by the bonding atoms.
  • In the case of a polar molecule, the end of the molecule that monopolizes electrons is partially negative and the other pole, which hardly ever gets to hold the bonding electron(s), is partially positive.
  • As such, every polar molecule has two poles––or has “dipoles.” The presence of dipoles in polar molecules is significant because they lay the foundation for hydrogen bonds. 15. Explain what hydrogen bonds are. - Hydrogen bonds are a noncovalent electrostatic attraction between two or more molecules or within a single large molecule. 17. Define the terms hydrophobic, hydrophilic, and amphipathic. - Hydrophobic is water fearing, which this name was applied to substances that are not readily dissolved in water.
  • Hydrophilic is water loving, which this name was applied to substances like sugar and other polar substances that are readily dissolved in water.

26. Describe glycosidic bonds, peptide bonds, and phosphodiester bonds. - The glycosidic bond is the covalent bond formed between monosaccharides to build complex sugars.

  • The peptide bonds are the type of bonds formed between amino group of one amino acid and the carboxyl group of the neighboring amino acid.
  • Phosphodiester bonds are bonds through which the sugar in one nucleotide bonds with a phosphate of another, creates the alternating pattern of sugar and phosphate seen on the backbone of DNA and RNA. 27. Explain the structural and functional characteristics of carbohydrates, lipids, nucleic acids, and proteins. - Carbohydrates are also known as polysaccharides (“many sugars”) since the smallest unit of a carbohydrate is a monosaccharide, or one sugar unit.
  • Function: Carbohydrates are the chief energy sources in biological systems, important structural biomolecules, and mediators of cellular adhesion, communication, and environmental sensing.
  • Lipids have diverse structures that range from long chains to complex cyclical structures. The fluidity of a lipid depends in part on the degree of saturation, or the number of double bonds that exist in the fatty acid hydrocarbon chains.
  • Function: Fats and oils serve as energy sources for cells, as cell structure components, and they help mediate cell signaling. Important structural lipids include phospholipids, which are common ingredients of the cellular membrane.
  • Nucleic acids are polymers of nucleotides consisting of three ingredients:
    1. A five-carbon sugar (deoxyribose in DNA; ribose in RNA)
    2. One to three phosphate groups
    3. A single nitrogenous base (adenine, guanine, cytosine, thymine, or uracil)
  • Function: DNA is the genetic blueprint of all cells, while viruses can use DNA or RNA as their genetic blueprint.
  • Proteins are polymers of amino acids that range from just a few amino acids to thousands. The average protein has about 300 amino acids. There are hundreds of amino acids, but only 22 are genetically encoded.
  • Function: There is tremendous diversity in proteins—our bodies make at least 30,000 different types. Proteins are essential to pretty much every process in a cell. 28. Compare and contrast deoxyribonucleotides and ribonucleotides. - Deoxyribonucleotides are the nucleotides that make up DNA , differs in sugar type.
  • Ribonucleotides are the nucleotides that make up RNA , differ in sugar type. 29. Summarize how saturation impacts lipid characteristics. - The fluidity of a lipid depends in part on the degree of saturation, or the number of double bonds that exist in the fatty acid hydrocarbon chains.
  • Saturated lipids do not have double bonds in their fatty acid chains and therefore have the maximum number of hydrogen-carbon bonds. Because saturated fatty acids pack tightly together, lipids high in saturated fatty acids, like butter and lard, exist as solids or semisolids at room temperature. 30. Describe the four levels of protein structure. - The four levels of protein structure are primary structure, secondary structure, tertiary structure, and quaternary structure.
  • Primary structure are when peptide bonds link amnio acids together.
  • Secondary structure are sheets of alpha-helices and beta-pleated.
  • Tertiary structures are three , globular structures characterized by noncovalent and covalent interactions.
  • Quaternary structure are when two or more polypeptide chains are needed.