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pathology for the health professions 2025 EXAM, Exams of Health sciences

pathology for the health professions 2025 EXAM A 41-year-old male undergoes surgery and has part of a population of stable cells removed. Which of the following best describes how the body will heal this defect? A. Stem cells will divide to replace the lost tissue B. The remaining quiescent cells will enter mitosis to replace the lost tissue C. Nothing will happen because stable cells cannot be replaced D. Fibrosis will scar the defect closed - Answers>>B. The remaining quiescent cells will enter the mitosis to replace the lost tissue A 65-year-old male has had uncontrolled hypertension for 30 years. As a result there are twice as many fibroblast cells (all of normal size) in his aorta than 30 years ago. This is best described as which of the following? A. Dysplasia B. Hyperplasia C. Hypertrophy D. Metaplasia - Answers>>B.Hyperplasia

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pathology for the health professions
A 41-year-old male undergoes surgery and has part of a population of stable cells
removed. Which of the following best describes how the body will heal this defect? A.
Stem cells will divide to replace the lost tissue B. The remaining quiescent cells will
enter mitosis to replace the lost tissue C. Nothing will happen because stable cells
cannot be replaced D. Fibrosis will scar the defect closed - Answers>>B. The remaining
quiescent cells will enter the mitosis to replace the lost tissue
A 65-year-old male has had uncontrolled hypertension for 30 years. As a result there
are twice as many fibroblast cells (all of normal size) in his aorta than 30 years ago.
This is best described as which of the following? A. Dysplasia B. Hyperplasia C.
Hypertrophy D. Metaplasia - Answers>>B.Hyperplasia
A cell is subject to hypoxic conditions for 20minutes, then observed under the
microscope. The nucleus has become shrunken, with marked condensation of the
chromatin. This nuclear change is best described as which of the following? A.
AutophagyB. Karyolysis C. Karyorrhexis D. Pyknosis - Answers>>D. Pyknosis
a diabetic patient has a wound that is slow to heal. why is this so? -
Answers>>microangiopathy leads to tissue ischemia
A new cell line is developed that completely lacks a smooth endoplasmic reticulum.
Which of the following functions would these cells be incapable of performing?
A.Degrading endocytosed materials
B.Maintaining cellular shape
C.Making new proteins
D.Synthesizing steroid hormones - Answers>>synthesizing steroid hormones
A new drug, Drug Y, is found to inhibit cyclooxygenase. Giving Drug Y is expected to
result in which of the following in test subjects? A. Decrease in arachidonic acid B.
Decrease in leukotrienes C. Decrease in prostaglandins D. Increase in inflammatory
response - Answers>>C. Decrease in prostaglandins
activation of which mediator of inflammation in circulating blood leads to formation of
bradykinin? - Answers>>hageman factor
Arachidonic acid is derived from which of the following sources? A. Cytoplasmic
proteins B. Extracellular proteins C. Phospholipids D. Nucleic acids - Answers>>C.
Phospholipids
aspirin functions as an antiinflammatory agent by in inhibiting the production of which
enzyme? - Answers>>cyclooxygenase
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pathology for the health professions

A 41-year-old male undergoes surgery and has part of a population of stable cells removed. Which of the following best describes how the body will heal this defect? A. Stem cells will divide to replace the lost tissue B. The remaining quiescent cells will enter mitosis to replace the lost tissue C. Nothing will happen because stable cells cannot be replaced D. Fibrosis will scar the defect closed - Answers>>B. The remaining quiescent cells will enter the mitosis to replace the lost tissue A 65-year-old male has had uncontrolled hypertension for 30 years. As a result there are twice as many fibroblast cells (all of normal size) in his aorta than 30 years ago. This is best described as which of the following? A. Dysplasia B. Hyperplasia C. Hypertrophy D. Metaplasia - Answers>>B.Hyperplasia A cell is subject to hypoxic conditions for 20minutes, then observed under the microscope. The nucleus has become shrunken, with marked condensation of the chromatin. This nuclear change is best described as which of the following? A. AutophagyB. Karyolysis C. Karyorrhexis D. Pyknosis - Answers>>D. Pyknosis a diabetic patient has a wound that is slow to heal. why is this so? - Answers>>microangiopathy leads to tissue ischemia A new cell line is developed that completely lacks a smooth endoplasmic reticulum. Which of the following functions would these cells be incapable of performing? A.Degrading endocytosed materials B.Maintaining cellular shape C.Making new proteins D.Synthesizing steroid hormones - Answers>>synthesizing steroid hormones A new drug, Drug Y, is found to inhibit cyclooxygenase. Giving Drug Y is expected to result in which of the following in test subjects? A. Decrease in arachidonic acid B. Decrease in leukotrienes C. Decrease in prostaglandins D. Increase in inflammatory response - Answers>>C. Decrease in prostaglandins activation of which mediator of inflammation in circulating blood leads to formation of bradykinin? - Answers>>hageman factor Arachidonic acid is derived from which of the following sources? A. Cytoplasmic proteins B. Extracellular proteins C. Phospholipids D. Nucleic acids - Answers>>C. Phospholipids aspirin functions as an antiinflammatory agent by in inhibiting the production of which enzyme? - Answers>>cyclooxygenase

basophils - Answers>><1%

  • bean shaped single nucleus
  • cytoplasm contains granules rich in vasoactive substances, such as histamine Cell A secretes substance 1. Substance 1 is taken up two cells away by cell B, which then responds by secreting substance 2. This interaction is best described as which of the following? A. Autocrine B. Endocrine C. Exocrine D. Paracrine - Answers>>D. Paracrine chronic hemolysis of red blood cells is characterized by accumulation of an iron- containing brown pigment in the cytoplasm of liver cells. what is this brown pigment called? - Answers>>hemosiderin chronic inflammation - Answers>>are marked by an exudate composed of lymphocytes, macrophages, and plasma cells cytoplasm - Answers>>A jellylike fluid inside the cell in which the organelles are suspended define atrophy - Answers>>denotes a decrease in the size of a cell, tissue, organ or the entire body. define hyperplasia - Answers>>increase in the size of tissues and organs caused by an increased number of cells define hypertrophy - Answers>>increase in the size of tissues or organs caused by enlargement of individual cells. define metaplasia - Answers>>form of adaptation characterized b the change of one cell type into another Endoplasmic Reticulum (RER) AND (SER) - Answers>>a meshwork of membranes that is continuous with the outer plasma membrane RER- is the site of protein synthesis for export and secretion SER-metabolic degradation of drugs, hormones, and various nutrients and the synthesis of steroid hormones. enlargement of the heart, caused by hypertension, is a result of which physiologic process? - Answers>>hypertrophy eosinophils - Answers>>- 2 - 3% of wbc
  • stain pink
  • prominent in allergic reactions
  • usually seen in chronic inflammation Fibrinous inflammation - Answers>>exudate that is rich in fibrin

polymorphonuclear neutrophils - Answers>>-primary cells that respond to bacterial infections

  • most abundant wbc
  • 60 - 70% of all wbc
  • very mobile Protein X is needed to help maintain two other proteins, both of which only exist in the cytoplasm of the cell. Where is protein X most likely synthesized? A.Free ribosome B.Nucleus C.Rough endoplasmic reticulum D.Smooth endoplasmic reticulum - Answers>>free ribosome pseudomembranous inflammation - Answers>>form of ulcerative inflammation that is combined with fibrinopurulent exudation purulent inflammation - Answers>>typically caused by pus-forming bacteria, such as streptococci and staphylococci Pyknosis irreversible cell injury - Answers>>condensation of the chromatin Ribosomes - Answers>>are small granules composed of RNA. serous inflammation - Answers>>considered the mildest form of inflammation, is characterized by the exudation of serum The inhibition of ATP production caused by hypoxia will result in which cellular outcome? - Answers>>dilation and fragmentation of the rough endoplasmic reticulum under what circumstance will inflammation fail to occur? - Answers>>in gangrenous tissue What are the cardinal signs of inflammation? - Answers>>Calor = heat Rubor = redness Tumor = swelling Dolor = pain Functio laesa = disturbed function what best describes hydropic change at the cellular level? - Answers>>a result of irreversible cell injury what does the center of an abscess contain? - Answers>>pus what happens when prostaglandins are released by pryogens in the hypothalamic thermoregulatory center? - Answers>>fever what is a characteristic feature of acute inflammation? - Answers>>it involves the rapid migration of neutrophils to the site of inflammation

what is inflammation? - Answers>>caused by infectious pathogens or by chemical and physical factors, foreign bodies, and immune mechanisms. what is the result of arteriole dilation? - Answers>>hyperemia what is the term used to describe a hypertrophic scar? - Answers>>keloid what might fibrinous inflammation be indicative of - Answers>>greater blood vessel damage and vessel permeability what type of irreversible cell injury is seen in myocardial infarction? - Answers>>coagulation necrosis when irritated by chronic exposure to cigarette smoke, columnar bronchial epithelium changes into stratified squamous epithelium. what is this physiologic change an example of? - Answers>>metaplasia Which of the following accounts for differences in cells in the human body? A.Differences in chromatin B.Differences in chromosomes C.Differential content of DNA D.Differential expression of genes - Answers>>differential expression of genes Which of the following best describes phagocytosis? A. Migration of a PMN out of a blood vessel B. Migration of a PMN to the site of injury C. Release of interleukins by a PMN D. Uptake of debris by a PMN - Answers>>D. uptake of debris by a PMN Which of the following best describes the type of necrosis very soft organs, such as the brain, typically undergo? A. Caseous necrosis B. Coagulative necrosis C. Fat necrosis D. Liquefactive necrosis - Answers>>D. Liquefactive necrosis Which of the following causes the redness and swelling associated with inflammation? A. Arteriolar constriction B. Arteriolar dilation C. Venule constriction D. Venule dilation - Answers>>B. Arteriolar dilation Which of the following cells is most likely to undergo apoptosis? A. A cell that has been anoxic for 30 minutes B. A cell that has stopped receiving growth signals C. A cell with sudden loss of function of mitochondria D. A large, swollen cell with distended nucleus - Answers>>B. A cell that has stopped receiving growth signals which of the following contributes to the delayed healing of the skin wound? - Answers>>increased corticosteroid levels Which of the following effects does bradykinin have that histamine does not have? A. Activates the coagulation cascade B. Acts faster C. Incites pain D. Increases vessel permeability - Answers>>C. Incites pain

intention in a 30-year-old female - Answers>>D. a small eye wound healing by primary intention in a 30 year old female Which set of lymphocytes is decreased the most in the blood of patients with AIDS? a. B-lymphocytes b. T-helper lymphocytes c. T-suppressor/cytotoxic lymphocytes d. Natural killer cells. E. Bone marrow stem cell precursor of lymphocytes - Answers>>C which statement best describes a fatty liver? - Answers>>There is an intracellular accumulation of triglycerides. which type of necrosis is found in the granulomas of pulmonary tuberculosis? - Answers>>caseous necrosis which vitamin is know to prevent scurvy and promote wound healing? - Answers>>vitamin c