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Zinnat: Package Leaflet for Cefuroxime Film-Coated Tablets, Lecture notes of Medicine

Thomas Edison State University (TESU)Medicine

Information for users about Zinnat, a film-coated tablet containing the antibiotic cefuroxime. It explains what Zinnat is used for, how to take it, possible side effects, and how to store it. The document also includes warnings for those with allergies or taking certain medications, as well as interactions with other medicines and food. Users are advised to consult their doctor or pharmacist for further information.

What you will learn

  • What are the possible side effects of taking Zinnat?
  • What precautions should be taken before taking Zinnat?
  • What is Zinnat and what is it used for?

Typology: Lecture notes

2021/2022

Uploaded on 09/12/2022

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Package Leaflet: Information for the user
Zinnat 125 mg and 250 mg film-coated tablets
cefuroxime
Read all of this leaflet carefully before you start taking this medicine because it
contains important information for you.
- Keep this leaflet. You may need to read it again.
- If you have any further questions, ask your doctor or pharmacist or nurse.
- This medicine has been prescribed for you only. Do not pass it on to others. It
may harm them, even if their signs of illness are the same as yours.
- If you get any side effects, talk to your doctor or pharmacist or nurse. This
includes any possible side effects not listed in this leaflet. See section 4.
What is in this leaflet:
1. What Zinnat is and what it is used for
2. What you need to know before you take Zinnat
3. How to take Zinnat
4. Possible side effects
5. How to store Zinnat
6. Contents of the pack and other information
1. What Zinnat is and what it is used for
Zinnat is an antibiotic used in adults and children. It works by killing bacteria that
cause infections. It belongs to a group of medicines called cephalosporins.
Zinnat is used to treat infections of:
• the throat
• sinus
• middle ear
• the lungs or chest
• the urinary tract
• the skin and soft tissues.
Zinnat can also be used:
• to treat Lyme disease (an infection spread by parasites called ticks).
Your doctor may test the type of bacteria causing your infection and monitor whether
the bacteria are sensitive to Zinnat during your treatment.
2. What you need to know before you take Zinnat
Do not take Zinnat:
• if you are allergic to cefuroxime axetil or any cephalosporin antibiotics or
any of the other ingredients of Zinnat (listed in section 6).
• if you have ever had a severe allergic (hypersensitive) reaction to any other
type of betalactam antibiotic (penicillins, monobactams and carbapenems).
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Partial preview of the text

Download Zinnat: Package Leaflet for Cefuroxime Film-Coated Tablets and more Lecture notes Medicine in PDF only on Docsity!

Package Leaflet: Information for the user

Zinnat 125 mg and 250 mg film-coated tablets

cefuroxime

Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.

  • Keep this leaflet. You may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist or nurse.
  • This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
  • If you get any side effects, talk to your doctor or pharmacist or nurse. This includes any possible side effects not listed in this leaflet. See section 4. What is in this leaflet:
  1. What Zinnat is and what it is used for
  2. What you need to know before you take Zinnat
  3. How to take Zinnat
  4. Possible side effects
  5. How to store Zinnat
  6. Contents of the pack and other information

1. What Zinnat is and what it is used for

Zinnat is an antibiotic used in adults and children. It works by killing bacteria that cause infections. It belongs to a group of medicines called cephalosporins. Zinnat is used to treat infections of:

  • the throat
  • sinus
  • middle ear
  • the lungs or chest
  • the urinary tract
  • the skin and soft tissues. Zinnat can also be used:
  • to treat Lyme disease (an infection spread by parasites called ticks). Your doctor may test the type of bacteria causing your infection and monitor whether the bacteria are sensitive to Zinnat during your treatment.

2. What you need to know before you take Zinnat

Do not take Zinnat:

  • if you are allergic to cefuroxime axetil or any cephalosporin antibiotics or any of the other ingredients of Zinnat (listed in section 6).
  • if you have ever had a severe allergic (hypersensitive) reaction to any other type of betalactam antibiotic (penicillins, monobactams and carbapenems).

➔ If you think this applies to you, don’t take Zinnat until you have checked with your doctor. Warnings and precautions Talk to your doctor or pharmacist before taking Zinnat. Children Zinnat is not recommended for children aged under 3 months , as the safety and effectiveness are not known in this age group. You must look out for certain symptoms, such as allergic reactions, fungal infections (such as candida ) and severe diarrhoea ( pseudomembranous colitis ) while you are taking Zinnat. This will reduce the risk of any problems. See ‘Conditions you need to look out for’ in Section 4. If you need a blood test Zinnat can affect the results of a test for blood sugar levels, or a blood screen called the Coombs test. If you need a blood test: ➔ Tell the person taking the sample that you are taking Zinnat. Other medicines and Zinnat Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. Medicines used to reduce the amount of acid in your stomach (e.g. antacids used to treat heartburn ) can affect how Zinnat works. Probenecid Oral anticoagulants ➔ Tell your doctor or pharmacist if you are taking any medicine like this. Contraceptive pills Zinnat may reduce the effectiveness of the contraceptive pill. If you are taking the contraceptive pill while you are being treated with Zinnat you also need to use a barrier method of contraception (such as condoms). Ask your doctor for advice. Pregnancy and breast-feeding and fertility If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine. Driving and using machines Zinnat can make you dizzy and have other side effects that make you less alert. ➔ Don’t drive or use machines if you do not feel well.

If you take too much Zinnat you may have neurological disorders, in particular you may be more likely to have fits (seizures). ➔ Don't delay. Contact your doctor or your nearest hospital emergency department immediately. If possible, show them the Zinnat pack. If you forget to take Zinnat Do not take a double dose to make up for a forgotten dose. Just take your next dose at the usual time. If you stop taking Zinnat Don’t stop Zinnat without advice It is important that you take the full course of Zinnat. Don’t stop unless your doctor advises you to – even if you are feeling better. If you don't complete the full course of treatment, the infection may come back. If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them. Conditions you need to look out for A small number of people taking Zinnat get an allergic reaction or potentially serious skin reaction. Symptoms of these reactions include:

  • severe allergic reaction. Signs include raised and itchy rash , swelling , sometimes of the face or mouth causing difficulty in breathing.
  • skin rash, which may blister , and looks like small targets (central dark spot surrounded by a paler area, with a dark ring around the edge).
  • a widespread rash with blisters and peeling skin. (These may be signs of Stevens-Johnson syndrome or toxic epidermal necrolysis ). Other conditions you need to look out for while taking Zinnat include:
  • fungal infections. Medicines like Zinnat can cause an overgrowth of yeast ( Candida ) in the body which can lead to fungal infections (such as thrush). This side effect is more likely if you take Zinnat for a long time.
  • severe diarrhoea ( Pseudomembranous colitis ). Medicines like Zinnat can cause inflammation of the colon (large intestine), causing severe diarrhoea, usually with blood and mucus, stomach pain, fever.
  • Jarisch-Herxheimer reaction. Some patients may get a high temperature (fever), chills, headache, muscle pain and skin rash while being treated with

Zinnat for Lyme disease. This is known as the Jarisch-Herxheimer reaction. Symptoms usually last a few hours or up to one day. ➔ Contact a doctor or nurse immediately if you get any of these symptoms. Common side effects These may affect up to 1 in 10 people:

  • fungal infections (such as Candida )
  • headache
  • dizziness
  • diarrhoea
  • feeling sick
  • stomach pain. Common side effects that may show up in blood tests:
  • an increase in a type of white blood cell ( eosinophilia )
  • an increase in liver enzymes. Uncommon side effects These may affect up to 1 in 100 people:
  • being sick
  • skin rashes. Uncommon side effects that may show up in blood tests:
  • a decrease in the number of blood platelets (cells that help blood to clot)
  • a decrease in the number of white blood cells
  • positive Coomb’s test. Other side effects Other side effects have occurred in a very small number of people, but their exact frequency is unknown:
  • severe diarrhoea ( pseudomembranous colitis )
  • allergic reactions
  • skin reactions (including severe)
  • high temperature ( fever )
  • yellowing of the whites of the eyes or skin
  • inflammation of the liver ( hepatitis ). Side effects that may show up in blood tests:
  • red blood cells destroyed too quickly ( haemolytic anaemia ).

Manufacturer: Glaxo Operations UK Ltd, Harmire Road, Barnard Castle, Co. Durham DL12 8DT Or GlaxoSmithKline Manufacturing S.p.A., Via A. Fleming, 2, 37135 Verona, Italy Other formats To listen to or request a copy of this leaflet in Braille, large print or audio please call, free of charge:

0800 198 5000 (UK Only)

Please be ready to give the following information: Product name Zinnat 125 mg film-coated tablets Zinnat 250 mg film-coated tablets Reference number 10949/ This is a service provided by the Royal National Institute of Blind People. This leaflet was last revised in November 2019. Trade marks are owned by or licensed to the GSK group of companies. © 2019 GSK group of companies or its licensor.