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A concise question-and-answer review of antibiotic medications, focusing on drug interactions, adverse effects, and treatment guidelines for common infections like mrsa and c. Difficile. It covers key considerations for antibiotic selection, including patient-specific factors such as pregnancy and allergies. The material is presented in a direct, question-answer format, making it useful for quick review and exam preparation. It also addresses important clinical considerations such as antibiotic resistance, adverse reactions, and drug interactions, enhancing its practical value for medical students and healthcare professionals. A valuable resource for medical students and healthcare professionals seeking a quick review of antibiotic medications and their clinical applications. It offers a concise and practical overview of essential concepts in antibiotic therapy, making it an excellent tool for exam preparation and clinical practice.
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Which antibiotic is the drug of choice for MRSA - ✔✔Beta-lactam antibiotic What is the first step in treating a MRSA Abscess? - ✔✔I&D with culture followed by CDC gold standard resource for plan of care and abx selection if necessary What is the risk of using tetracycline and calcium/dairy products? - ✔✔Chelate formation from the calsium What abx is associated with serious adverse effects of hyperkalemia? - ✔✔Trimethoprim-sulfamethazole Trimethoprim-sulfamethazole plus this med increases risk of hyperkalemia and sudden cardiac death? - ✔✔ACE Inhibitor or angiotensin receptor blocker Most serious Warfarin/drug interaction - ✔✔Trimethoprim-Sulfamethazole will increase INR and risk bleeding These drugs increase INR in pts taking warfarin - ✔✔TMP-SMX, erythromycin, fluconazole, ketoconazole, itraconazole, metronizadole Simvastatin or Lovestatin are HMG-CoA ihibitors metabolyzed by CYP3A4 system and should not be taking with what drug? - ✔✔Biaxin (clarithromycin) Clarithrymycin interacts with these drugs to cause severe kidney injury - ✔✔Calcium Channel blockers Fluoroquinolone/levofoxacin (Levaquin) can cause tendon rupture in what patients? - ✔✔Over 60, with corticosteroids, organ transplant patients. Risk factors for development of antibiotic resistant Otitis Media - ✔✔Day care, less than 2 years old, abx in last 3 mths, winter/spring, local resistance pattern via antibiogram
Gram Positive Pathogens - ✔✔1. Staph, 2. Strep, 3. Enterococci Why does C.Diff result? - ✔✔C. Diff colonizing the normal gut flora resulting in toxin release Four abx that cause C.Diff - ✔✔1. Imipenem,
If your patient is betalactram resistant you should prescribe - ✔✔3rd generation cephalosporin or extended spectrum pcn antivirals work by - ✔✔blocking entry into cells and preventing reproduction and viral shedding Many HIV patients have interactions with which drug - ✔✔sulfa drugs Antifungal "azoles" contraindication - ✔✔Statin drugs but not vaginal miconazole or flagyl (metonidazole). QT prolongation drugs lengthy fungal tx with azoles can cause - ✔✔hepatotoxicity with long term tx which is usual