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Pharmacology NURS 251 Module 9 Exam
1. Select the characteristic below that is consistent with a specialty medica- tion. ANS treat a
complex disease state
2. True or False. Patients must go through a specialty pharmacy to obtain a medication that is
considered a specialty medication; retail pharmacies do not stock them. ANS True
3. List three characteristics of specialty medications. ANS 1. Stock high cost med- ications
2. Holds medications that are specific to complex diseases
3. Sometimes involves a case manager to monitor the patient
4. List three classes of medications that are considered specialty medica- tions. ANS 1.
immunomodulating drugs
2. anti-TNF monoclonal antibody
3. HAART
5. Match the disease state with the statement that is true of that disease. ANS Can- cer - involves the
development of abnormal Multiple Sclerosis - involved the CNS RA - autoimmune disorder Crohn's disease - inflammation in the digestion tract Hepatitis C - virus that lead to liver damage HIV - bodys own immune system is attacked
6. True or False. The initial treatment for Rheumatoid arthritis includes a class of medications called
DMARDS (disease modifying anti-rheumatic drugs). ANS - True
7. Select the true statement regarding HIV.
It was first identified in the early 1990s It attacks the CD-4 cells It is spread through respiratory secretions With recent medical advancements a cure is now possible. ANS it attacks the CD-4 cells
Bevacizumab Natalizumab Aldesleukin Anakinra Abatacept Etanercept ANS Interferon beta-1a - Avonex Adalimumab - Humira Bevacizumab - Avastin Natalizumab - Tysabri Aldesleukin - Proleukin Anakinra - Kineret Abatacept - Orencia Etanercept – Enbrel
13. Select the false statement regarding interferon beta-1a.
It is marketed under the brand names Avonex and Rebif Avonex is a once weekly subcutaneous injection
You Answered It is indicated to treat relapsing multiple sclerosis Common adverse events include flu like symptoms ANS Avonex is a once weekly subcutaneous injection
14. What is the name of the severe toxicity associated with aldesleukin (Pro- leukin)? ANS Capillary
leak syndrome
15. What type of cell produces lymphokines? ANS Lymphocytes
16. True or False. In order to take natalizumab, the patient must be enrolled in a patient safety
program due to the risk of heart failure exacerbation. ANS False
17. What class of immunomodulating drugs used to include the mainstay of treatment for hepatitis
C? ANS interferons
18. Select the false statement regarding recent advancements in Hepatitis C treatment.
Cure rates are now over 95% The new treatments are extremely expensive Treatment lasts 8-12 weeks The mechanism is essentially aimed at boosting the patient's natural immune response. ANS The mechanism is essentially aimed at boosting the patient's natural immune response.
19. True or False. Viekira pak was the regimen that launched the radical change in the treatment of
Compliance is critical to the success of these drugs All HIV medications essentially work by the same mechanism ANS Compliance is critical to the success of these drugs
25. Match the class of antiretroviral with its mechanism of action.
NRTI
NNRTI
Protease Inhibitor Integrase Inhibitor Fusion Inhibitor ANS NRTI - incorporate themselves into the DNA inhibiting reverse transcriptase NNRTI - binds to reverse transcriptase and prevents it from working Protease Inhibitor - preventing the final assembly of the new virus Integrase Inhibitor - prevent the virus from being able to enter the nucleus Fusion Inhibitor - prevent the virus from binding completely to the host cell
26. What does HAART stand for? ANS Highly active antiretroviral therapy
27. True or False. Compliance to HIV medications can delay the development of drug resistance.
ANS True
28. Which interleukin covered in this module exerts its effect by inhibiting the immune system? ANS
interleukin-
29. True or False Natalizumab is derived from murine myeloma cells? ANS True
30. Match the immunomodulating Drug with the correct indication
Interferon beta 1-a Adalimumab Bevacizumab Aldesleukin Abatacept ANS Interferon beta 1-a - MS Adalimumab - Crohns Disease Bevacizumab - Colorectal Cancer Aldesleukin - Melanoma Abatacept - RA
31. Which of the following immunomodulating drugs is available in a subcu- taneous dose? ANS
Anakinra
32. Which of the following should a patient not expect when going through a specialty pharmacy
to obtain a medication? ANS To meet with the pharmacist face-to-face
