3rd Pharm D, Pharmacology-II
Rajiv Gandhi University of Health Sciences (RGUHS):
Short Q&A on Pharmacology of Drugs acting on Renal system.
1. Name four vasopressin analogues?
Answer: Vasopressin analogues are the drugs which function similar to vasopressin but differ
in chemical structure.
Examples of vasopressin analogues are:
• Desmopressin
• Terlipressin
• Lypressin
• Felypressin
2. Name any two ADH and its two uses.
Answer: ADH is secreted by posterior pituitary gland and has anti-diuretic effect.
Examples of ADH are:
• Desmopressin:
Uses- Used in treatment of Diabetes Insipidus (DI) of pituitary origin also known as
neurogenic DI or central DI.
• Terlipressin:
Uses- Used for treatment of bleeding oesophageal varices.
OR
DRUG
USES
Desmopressin
Used in treatment of Diabetes Insipidus
(DI) of pituitary origin also known as
neurogenic DI or central DI.
Terlipressin
Used for treatment of bleeding
oesophageal varices.
3. Define carbonic anhydrase inhibitors? Give two examples.
Answer: Carbonic anhydrase inhibitors are the class of drugs which primarily act on the
Carbonic anhydrase enzyme and inhibit their activity of reabsorption of HCO3- and Na+ and
thereby promoting its diuresis.
Examples of Carbonic anhydrase inhibitors are:
• Acetazolamide
• Methazolamide
Carbonic anhydrase inhibitor
Carbonic anhydrase enzyme Inhibi�on of HCO3- and Na+ reabsorp�on.
Diuresis of HCO3-
