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QUESTIONS WITH CORRECT ANSWERS
- The study of drug absorption, distribution, metabolism, and excretion is known as A. pharmacotherapeutics B. pharmacodynamics C. pharmacokinetics D. pharmacy E. posology: C
- The medical situation when a particular drug should not be administered is referred to as A. side effect B. adverse effect C. drug allergy D. contraindication E. antagonism: D
- An unusual or unexpected drug reaction by an individual is known as A. toxic effect B. antagonism
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C. idiosyncrasy
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B. OTC drug C. prescription drug
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D. controlled substance E. nonproprietary drug: D
- Select the term below that relates to the amount of drug administered to produce a therapeutic effect. A. posology B. toxicology C. pharmacodynamics D. pharmacotherapeutics E. pharmacy: A
- A medication that does not require a physician's service to obtain is referred to as A. trade B. nonproprietary C. nonprescription D. brand E. generic: C
- Which of the following could be categorized as an adverse reaction?
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B. drug allergy C. teratogenicity D. carcinogenicity E. all of these: E
- The time a drug continues to produce its effect is its A. ED B. maximal response C. ceiling effect D. onset of action E. duration of action: E 11.. The drug administration route demonstrating the slowest onset of action is A. inhalation B. transdermal C. intramuscular D. sublingual E. intravenous: B
- In order for drugs to cross the blood-brain barrier, they must be A. ionized
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B. positively charged C. water soluble
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drugs, the process is termed
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A. first-pass metabolism B. enzyme induction C. enzyme inhibition D. enterohepatic cycling E. microsomal inhibition: B
- The rate of drug absorption would be increased by which of the follow- ing? A. drug ionization B. water solubility C. positively charged drug D. negatively charged drug E. lipid solubility: E
- Which factor of individual variation is dependent upon the patient's attitude toward treatment? A. weight B. age C. genetic variation D. placebo effect E. gender: D
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- A 36-year-old male has been diagnosed with chronic myeloid leukemia. His oncologist discusses treatment options with him. The patient is glad to hear that novel anticancer drugs used to treat chronic myeloid leukemia have a much better risk-benefit ratio than older ones, due to their improved selectivity. A major determinant for the selectivity of a given drug is A) its target receptor ligand affinity. B) its target receptor cell-type distribution. C) its ionic interactions. D) its hydrogen bonding. E) its intrinsic activity.: B
- A 56-year-old man with chest pain is diagnosed with stable angina and treated with several drugs including nitroglycerin. Every day he has to discontinue nitroglycerin for some hours to re-establish reactivity of his body to the drug. The clinical observation of a rapidly decreasing response to nitroglycerin after administration of just a few doses is called
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idiosyncrasy. tachyphylaxi s. heterologous desensitization. refractoriness. receptor downregulation.: B
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B) a competitive receptor antagonist. C) a noncompetitive receptor antagonist. D) a partial agonist. E) an inverse agonist.: A
- The main pharmacologic effect of norepinephrine on alpha- receptors is A. increased heart rate B. bronchodilation C. vasoconstriction D. contraction of urinary bladder E. increased force of myocardial contraction: C
- The pharmacologic effect of IV metaraminol (an alpha-1 drug) is A. vasodilation B. vasoconstriction C. cardiac stimulation D. cardiac depression E. bronchodilation: B
- Epinephrine stimulates A. alpha-1 receptors
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B. alpha-2 receptors C. beta-1 receptors
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D. formation of a false transmitter in adrenergic nerve ending
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E. none of these: D
- The drug of choice to treat acute allergic reactions is A. norepinephrine B. phenylephrine C. pseudoephedrine D. epinephrine E. propranolol: D
- Which of the following are actions of nonselective beta- adrenergic blocking drugs? A. decreasing heart rate B. decreasing force of myocardial contraction C. vasoconstriction of skeletal muscle blood vessels D. lowering of blood pressure E. all of these: E
- The actions of epinephrine (EPI) include which of the following? A. bronchodilation B. vasoconstriction C. relaxation of uterus D. increased heart rate
