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PRITE 2020 CORRECT QUESTIONS &
VERIFIED CORRECT ANSWERS (GRADED A+)
"key component of collaborative care programs that integrate mental health services into
primary care settings? - CORRECT ANSWER care management"
"Feelings of persecution are most reflective of which of the following defense mechanisms?
- Denial
- Projection
- Repression
- Regression
- Reaction formation - CORRECT ANSWER Projection" "Visual hallucinations - wavy distortions, both visual fields Vertigo dysarthria tingling in both hands and feet perioral numbness
occipital headache - CORRECT ANSWER Basilar migraine"
"slap the pal, of his hand on his knee, alternating with the back of his hand, in rapid succession-
abnormality in this indicates? - CORRECT ANSWER dysdiadochokinesia"
"NMDA receptor mechanism - CORRECT ANSWER Ionotropic receptor causes
depolarisation. Mg2+ block relieved by depolarisation. Permeable to Na+ and Ca2+ influx-" "The patient begins fearing symptoms of pancreatic cancer after death of a parent from pancreatic cancer. He feels the need to weigh himself to be reassured that he is not losing weight. Avoids seeing the doctor due to fear of being diagnosed. -OCD -delusional -somatic symptoms do
- illness anxiety disorder
- conversion do - CORRECT ANSWER Illness anxiety They perform excessive health-related behaviors maladaptive avoidance- cancels doctor's appts atleast 6 months specifiers:
- care seeking type
- care-avoidant type" "process of identifying problem areas in workflow and eliminating potential waste?
- SMART goals Demin principles Lean Methodology Medical home model
Plan Do Study Act Cycle - CORRECT ANSWER Lean methdology"
"area of hippocampus contains stem cells involved in neurogenesis - CORRECT ANSWER
Sub-granular zone" "Disruption of salience network would affech which? -attention -decision-making -working memory -internal cognition
-detection of relevant stimuli - CORRECT ANSWER detection of relevant stimuli
default mode network - medial prefrontal cortex, medial temporal lobe, medial parietal cortex. Function includes thoughts not associated with the immediate environment. Consolidates information and memories salience = anterior cingulate cortex, right anterior insula, left anterior insula" "As one nears midlife, what is the most typical developmental sceniaro?
- focus solely on one's career
- Depression in parents whose last child is leaving home
- A reappraisal of one's marriage and committed relationships
- abrupt significant changes that appear impulsive in nature
- Increase difficulty adjusting to a change from a youthful appearance - CORRECT ANSWER Reappraisal of one's marriage and committed relationships."
"Erikson Stage 1 - CORRECT ANSWER Trust vs. Mistrust
0-1.5 months "Can I trust the people around me" Basic virtue: Hope Important event: Feeding"
"Erikson stage 2 - CORRECT ANSWER Autonomy vs. Shame and Doubt
-Comprehending conservation of volume -Coordinating catching and throwing a ball -Describing narratives primarily from self-view
- Understanding the difference between right and wrong - CORRECT ANSWER Comprehending conservation of volume"
"At what age does grey matter reach peak? - CORRECT ANSWER late childhood"
"at what age/stage of development does the peer group become an important mediator of aggression, especially in vulnerable males? -preschool (4y) -early school age (7y) -late school (10y) -early adol (13y)
-late adol (16y) - CORRECT ANSWER late school (10y)"
"BDNF acts on which receptor?
- Pan neutrophin
- NMDA
- Insulin growth factor 1
- 5 HT1A
- Tropomyosin receptor kinase B - CORRECT ANSWER Tropomyosin receptor kinase B" "Trisomy 21- 3 copies of gene coding which protein? -Presenlin 1 protein
- presenelin 2 protein
- APOE-E -APOE-E
- Amyloid precursor protein (APP) - CORRECT ANSWER Amyloid precursor protein (APP)"
"PCR is genetic linkage studies do what? - CORRECT ANSWER amplification of microsatellite
markers"
"Which anti-epipleptic can cause bone loss? - CORRECT ANSWER Valproate"
"Relative intensity of DNA transcription acitivity determined by? -microRNA -Telomere length -DNA methylation -Non-coding RNA
-histone acetylation - CORRECT ANSWER histone acetylation"
"Molecular mechanism explaining how early life development contributes to psychiatric
disorders? - CORRECT ANSWER DNA methy"
"Which gene is seen in 90-100% of pt with narcolepsy? - CORRECT ANSWER HLA-DR2"
"Strongest genetic contribution in depressive disorder? - CORRECT ANSWER Cyclothymia"
"term for test actually measures what it is suppose to measure? -Validity -Stability -Reliability -specificity
-standardization - CORRECT ANSWER Validity
Reliability is an indicator in the amount of variability in a testing method" "which of the following is largely unbound to serum proteins and has limited sign. drug int.? -modafinil -donepezil -memantine -galantamine
-rivastigmine - CORRECT ANSWER rivastigmine"
"How does melatonin behave during sleep-wake cycle? - CORRECT ANSWER Levels begin to
increase 2 hrs before sleep onset and peak midway through the sleep period" "Which neuroscientist suggested psychotherapy would change gene expression?
- Eric Kandel
- Adolf meyer
- george endel -otto kronberg
- nancy andreason - CORRECT ANSWER Eric Kandel" "_________________________ is among the least-understood regions of the human brain. It has been proposed that the OFC is involved in sensory integration, in representing the affective value of
reinforcers, and in decision-making and expectation. - CORRECT ANSWER orbitofrontal
circuit"
"Which of the following are first rank symptoms of schizophrenia (Kurt Schneider)? depressed mood voices arguing waxy flexibility blunted affect
paranoia - CORRECT ANSWER voices arguing"
"which of the following structures is part of the hippocampal formation? amygdala septal area dentate gyrus cingulate gyrus
mamm bodies - CORRECT ANSWER dentate gyrus"
"which of the following is the most preserved in an older adult? verbal ability simple recall encoding ability psychomotor speed
speed of learning new material - CORRECT ANSWER verbal ability"
"_______________ age is women's most likely at risk for completing suicide? - CORRECT
ANSWER 55"
"__________________ is the term for inappropriate and uncontrollable laughter, best evidence for use
in MS is which medication? - CORRECT ANSWER pseudobulbar affect
Tx: amitriptyline Most common neuro dz with pseudobulbar would be multiple system atrophy tx: Dextromethorphan" "Which of the following is affected earliest in course of Alz dz? Amygdala Frontal lobe basal ganglia occipital lobe
hippocampus - CORRECT ANSWER hippocampus"
"____________________ is the most significant risk fx for development of primary enuresis? -
CORRECT ANSWER Family hx"
"What happens biologically in gradual decline in sexual responsivements in men as they age? Loss of penile elasticity increase in adrenal androgens reduction in genital bloodflow increase in circulating estrogen
increase in testosterones binding globulin - CORRECT ANSWER increase in testosterones
binding globulin" "_________________ is another term for poverty of speech and content alogia anomia agnosia alexithymia
apraxia of speech - CORRECT ANSWER alogia
19 yo pt reported hearing a voice that talked about what pt was thinking. The pt's speech has a normal rate and rhythm, but says things such as, "It is white, very white. I know. Things are that way. They are. I am."" "______________________ is when pt has signficant word finding difficulties when attemption to label pictured objects. But patient is able to describe how to use the object. alogia anomia agnosia alexithymia
apraxia of speech - CORRECT ANSWER anomia"
"________________inability to interpret sensations and hence to recognize things, typically as a result of brain damage. alogia anomia agnosia alexithymia
apraxia of speech - CORRECT ANSWER agnosia"
"_______________________inability to identify and describe emotion's experienced alogia anomia agnosia alexithymia
-test -cortisol
- incr. progesterone - CORRECT ANSWER test"
"orexin neurons involved in sleep wake cycle is where? - CORRECT ANSWER Lateral
hypothalamus- suprachiasmatic nuclei"
"more incarcerations between 1980s and 2010 attributed to? - CORRECT ANSWER
mandatory minimum sentences for drug related offenses"
"Which has highest measurement of disability adjusted life years (DALYs)? - CORRECT
ANSWER Depressive disorders"
"what is it called when ratings are similar across different raters? - CORRECT ANSWER
highly reliable"
"Leg weakness would be caused by occlusion of which artery? - CORRECT ANSWER Anterior
cerebral artery -contralateral leg weakness and sensory loss
- mild or no upper limb involvement -balance problems
- left-sided = aphasia" "agraphia of left hand inability to name objects placed in the left hand when eyes are closed
inability to read from left visual field - CORRECT ANSWER lesion of Corpus callosum
cant understand things on one side. NOT hemineglect." "Idiopathic park vs. drug onset park, which one is asymmetrical vs. symmetrical onset of
symptoms - CORRECT ANSWER idiopathic = classical symptoms
-tends to be asymmetrical onset and progression of motor symptoms drug-onset: symmetrical"
"Camptocromia - CORRECT ANSWER abnormal, severe and involuntary forward flexion of
the thoracolumbar spine Multi system atrophy"
"primary gustatory cortex - CORRECT ANSWER processes taste information; located in
insula"
"most specific lab test for heavy alcohol consumption? - CORRECT ANSWER carb deficient
transferrin Carbohydrate deficient transferrin (CDT) is the most specific serum biomarker of heavy alcohol consumption, defined as ≥ 350-420 g alcohol/week. Despite introduction of a standardized reference measurement technique, widespread use of CDT remains limited due to low sensitivity" "type of gait for NPH -magnetic -propulsive -tandem -scissor
-spastic - CORRECT ANSWER Magnetic
inability to lift feet off the floor with wide base propulsive, spastic = park gait"
"what causes scissor gait? - CORRECT ANSWER Cerebral palsy"
"highest affinity for human CB-1 receptor - CORRECT ANSWER anandamide"
"refer schizophrenia patient to rehab vocational program, what kind of prevention? - CORRECT
ANSWER tertiary"
"what does term "expressed emotion" refer to in family therapy? - CORRECT ANSWER Level
of criticism and hostility in family" "if patient is new onset episodes of excessive salivation, chewing, and choking sensation, the seizure originates where? -frontal insula -frontal operculum -mesial temp lobe singular gyrus -occipital lobe
-dorsolateral frontal lobe entorhinal cortex - CORRECT ANSWER frontal operculum
anterior insula nd frontal operculum make up the primary gust. cortex"
PAPP-A is decreased in all trisomies. Nuchal translucency is increased in all trisomies. Inhibin A is only increased in Down's syndrome. Beta-HCG is increased in Down's syndrome"
"Histamine production occurs in only which part of the brain? - CORRECT ANSWER
Hypothalamus (tuberomammillary nucleus)" “The primary taste cortex in humans:
- Dorsolateral
- Orbitofrontal
- Anterior insulra -Somatosensory
- Posterior temporal - CORRECT ANSWER Anterior insular"
"Which area requires public schools to provide edu resources for children with disabilities -
CORRECT ANSWER federal government"
"Patient is not able to produce 11 words starting with letter P but can name 12 animals. Where is the injury?
- Normal -Frontal lobe
- Parietal
- Factitious
- Temporal - CORRECT ANSWER Frontal" "Ambigious results on multiple sleep latency test. What would confirm narcolepsy?
- Genetic analysis
- Auto antibody test
- EEG
- CSF orexin
- PET scan - CORRECT ANSWER CSF orexin" "Which of the following changes in people over age 65 most likely responsible for increased risk of chronic subdural hematoma?
- Cortical atrophy
- lacunae in the basal ganglia
- Thickening and ossification of dura mater
- Occlusions of small penetrating cerebral arteries
- Increase permeability of BBB - CORRECT ANSWER Cortical atrophy"
"Improvement tool used to identify as many possible causes for an effect or problem and sort
ideas into useful diagnosis? - CORRECT ANSWER Fishbone diagrams"
"Which of the following circuits mediates the ability to resist responding to aggravating situations with hostility?
- papez
- dorsolateral -orbitofrontal -frontoparietal
-anterior cingulate - CORRECT ANSWER orbitofrontal = inhibition center
anterior cingulate cortex = emotions, impulse control Salience network = right ant insula --> anterior cingulate cortex --> left ant insula default mode network = posterior cingulate, left and right parietal, OFC" "Patient becomes increasingly annoyed at therapist and says "you must hate me." Defense mechanism?
- projection
- projective identification
- reaction formation
- displacement
- resistance - CORRECT ANSWER Projection- patient projected feelings of therapist on to herself Projective identification- when a person projects their own thoughts/beliefs on to another person, that other person believes that to be true."
"Which psychiatric disorder is most common with epilepsy? - CORRECT ANSWER MDD"
"Enhancement of dopamine transmission in which tract is associated with addicting and reinforcing effects of repeated exposre to psychostimulant drugs?
- Mesolimbic
- Nigrostriatal
- Mesocortical
- Corticostriatal
- Tuberoinfindubular? - CORRECT ANSWER Mesolimbic"
"Which neurostimulation modalities has received FDA approval for recurrent MDD? -
CORRECT ANSWER Vagus nerve stimulation"
"Cant read or write but has verbal fluency- where is the defect? - CORRECT ANSWER Left
POSTERIOR cerebral artery = angular gyrus effects cognition and language
"higher rate of ADHD and OCD in 6-12 year old boys attributed to? - CORRECT ANSWER loss
of grey matter in basal ganglia" "secondary mania most likely to occur in which of the following illness? -hepatitis -addison dz
- MS
- parkins do
- hyperparatyhroidism - CORRECT ANSWER MS" "Difference between effectiveness study vs. efficacy study?
- blind assignments
- random assignments
- real world conditions
- restrictive inclusion criteria
- circumscribed clinical population - CORRECT ANSWER real world conditions" "Psychoeducation component of CBT for adolescents often utilizes which of the following tx strategies?
- eliciting info about family dynamics -self-monitoring of emotionsal states with daily diaries
- social skills training to enhance psychosocial interactions
- behavioral assessment through clinical interview and screening tools
- obtaining information about the patient's academic performance from teachers - CORRECT
ANSWER self-monitoring of emotional states with daily diaries"
"Patient has inability to recognize objects based on touch- where is the defect?
- medial frontal
- anterior frontal
- anterior parietal
- posterior pareital
- medial temporal - CORRECT ANSWER posterior parietal lobe"
"How do you define a tic? - CORRECT ANSWER sudden
rapid recurrent non-rhythmic motor movement or vocalization" "Both motor AND one or more vocal tics have been present during the illness, although not concurrently Duration: 1 year, waxing and waning is fine
onset before age 18 - CORRECT ANSWER Tourette's"
"motor OR vocal tics, but not both motor and vocal - CORRECT ANSWER Persistent Motor or
Vocal tic disorder specify- with motor tics only or vocal tics only" "Single or multiple and/or vocal tics
less than 1 year - CORRECT ANSWER Provisional tic disorder"
"Adjunctive tx shown to reduce symptoms and improve biomarkers for inflammation and oxidative stress?
- kava
- glycine
- valerian
- st johns wort
- NAC - CORRECT ANSWER NAC"
"Developmental disability associated with triple repeat genetic abnormality? - CORRECT
ANSWER Fragile X"
"What is the repeat of fragile X syndrome? - CORRECT ANSWER CGG
decreased or absent levels of fragile X mental retardation protein (FMRP) Expansion of >200 repeats is known as full mutation and leads to methylation-coupled silencing of the FMR1 gene and absence of FMRP (protein) A smaller expansion of between approximately 50 to 55 and 200 repeats is known as premutation"
"Which disorder has CAG repeat? - CORRECT ANSWER Huntington's disease"
"4 yo child was hypotonic as an infant and is now exhibiting develop delays, foraging for food and
having many temper tantrums - CORRECT ANSWER Prader Willi syndrome
pathogenic copy number variants affecting DNA basepairs"
"Most common cause for syndromic obesity? - CORRECT ANSWER Prader Willi"
"Where is the genetic defect for Prader Willi? - CORRECT ANSWER Long arm of chromosome
15- paternal deletion (maternal imprinting)
"What would EMG show in Duchenne's muscular dystrophy? - CORRECT ANSWER small,
short-lasting motor unit potentials with increased recruitment dystrophin gene in mutated"
"ODD vs. Conduct Disorder - CORRECT ANSWER In ODD, children do not seriously violate the
rights of others or ignore their feelings. They rarely engage in activities that cause physical harm to others, and as a rule, they do not engage in criminal activity. ODD may precede a diagnosis of Conduct Disorder." "Which of the following is the most abudant circulating steroid in women? -cortisol -estrogen -progesterone -DHEA
- ACTH - CORRECT ANSWER DHEA"
"What does depakote do to Lamictal - CORRECT ANSWER Depakote inhibit (note that it is
not related to CYP) Lamictal metabolism and cause INCREASING Lamictal level Lamictal is well known for Risk of Rash and Steven-Johnson Syndrome" "Which of the following is most useful in dx of conversion disorder with sensory loss of left leg? -Standard EEG
- Quantative EEG -Evoked potentials -magneto-EEG
-MRI - CORRECT ANSWER Evoked potentials
On clinical grounds, somatosensory evoked potentials (SEP) and motor evoked potentials (MEP) are currently used to discriminate between hysterical and neurological conditions." "Histone phosphorylation is linked to a. transcription b. DNA Repair c. chromosome condensation d. cell cycle condensation
e. all of the above - CORRECT ANSWER Chromosome condensation
Causes early response gene induction" "Which of the following types of neurons ceases firing entirely during REM sleep? -histamine -muscarnic
-cholinergic -serotonergic
-noradrenergic - CORRECT ANSWER serotonergic"
"4 ethical principles of medicine - CORRECT ANSWER "the principles approach"
- autonomy
- beneficence
- nonmaleficence
- justice" "Which of the following methods of indentifying genetic disorder is best suited to localize genes that have a single or major effect within a genetically related family? -Linkage analysis -association mapping -candidate gene studies -next-gen sequencing
-comparative genomic hybridization - CORRECT ANSWER linkage analysis"
"linkage analysis - CORRECT ANSWER Genetic research strategy in which occurrence of a
disorder in an extended family is compared with that of a genetic marker for a physical characteristic or biological process that is known to be located on a particular chromosome." "Which of the following describes post-transcriptional genetic reg. mech. that likely contributes to genetic abnormalities?
- alternative splicing within the same gene -binding of a competing, inh. factor on the binding site -binding of hormones to response elements in inducible genes -using different transcription start sites, stop sites, and promoters in a gene
-binding of tissue specific transcrip factors to activation sites in single genes - CORRECT
ANSWER alternative splicing within the same gene"
"Courts have rule that physicians can ask and counsel patients about guns, based on which of the following physician's rights? -freedom of speech -protection from malpractice -to set clinical stadards of care -to protect oneself from patient violence
-to practice within the scope of their license - CORRECT ANSWER freedom of speech"
"Patient takes diazepam before EEG, what will it show? -beta waves -alpha waves
