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: Ethical Conduct for Research Involving Humans, specifically the CORE (Course on Research Ethics). The TCPS 2 provides ethical guidelines for research involving humans, including their data and biological materials
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You have already answered this question Minimal-risk research projects do not need to be reviewed by a full REB. A delegated review may be conducted by one or more REB members. False (your answer) True - ✔✔True A new virus is spreading among human populations, and the mechanisms that explain how it spreads are not well defined. One theory is that the virus is spread from person to person in workplaces due to mosquitoes. If this theory is true, installing mosquito nets in workplaces would sufficiently protect employees from this new virus. However, the scientific data do not allow for the moment to determine if this hypothesis is correct. While an epidemic is raging in a foreign country, a Canadian researcher affiliated with an institution eligible for agency funding proposes a research protocol whose objective is to verify this hypothesis. The study methodology basically consists of recruiting employees working for different employers and randomly assigning them to group A (use of mosquito nets) or group B (control group not using mosquito nets). Subsequently, the relative effectiveness of the nets will be evaluated accordi - ✔✔NOPE The researcher should end the study, as it now has no potential benefit. You have already answered this question A researcher from a Canadian institution eligible for agency funding wants to determine the frequency of cannabis use among high school students in Canada. The researcher plans to create a website that will contain a secure link to a survey that students who wish to participate in the research can complete. For scientific reasons, only students who have ever used cannabis will be invited to participate in the survey and answer it anonymously (answer all questions with YES or NO). The researcher believes that it is likely that some high school students who will respond to the survey come from an Aboriginal community. However, the researcher does not intend to include Aboriginal identity in his analysis of the results. In addition, it will not be possible for the researcher to know which participants come from Aboriginal communities, since the research does not include socio-demo - ✔✔NO Which of the following statements is true? (choose all that apply) According to the TCPS2, consent should be voluntary, informed and ongoing. (your answer) In research with underage participants, parents always have the final say on their participation.
In certain circumstances, deviations from the general principles of consent are acceptable. In certain circumstances, waivers of the requirement to document the consent process are acceptable. In the vast majority of cases, consent must be obtained prior to a participant's participation in research. (your answer) Wrong - ✔✔ A researcher from a Canadian institution eligible for agency funding wants to determine the frequency of cannabis use among high school students in Canada. The researcher plans to create a website that will contain a secure link to a survey that students who wish to participate in the research can complete. For scientific reasons, only students who have ever used cannabis will be invited to participate in the survey and answer it anonymously (answer all questions with YES or NO). The REB administrator considers the proposed research project to be minimal risk research. It therefore determines that a delegated evaluation can be done rather than an evaluation in the full committee. Is the REB administrator correct in believing that this is minimal risk research and in providing for delegated review rather than full committee review? NOPE YES (your answer) - ✔✔NOPE A full committee evaluation would be preferable in this case since the study will be done with minors and the questions asked of the participants could lead them to reveal personal information, sensitive information and to admit to having taken part in activities illegal. Also, it is illegal in some places to involve minors in research. You have already answered this question A researcher from a Canadian institution eligible for agency funding wants to determine the frequency of cannabis use among high school students in Canada. The researcher plans to create a website that will contain a secure link to a survey that students who wish to participate in the research can complete. For scientific reasons, only students who have ever used cannabis will be invited to participate in the survey and answer it anonymously (answer all questions with YES or NO). Some REB members disagreed with the researcher's methodological decision to exclude from the study students who had never used cannabis. According to them, such an exclusion will decrease the probability that the researcher manages to publish the results in a prestigious journal. Should the REB compel the researcher to modify the research protocol for this reason? NOPE YES (your answer) - ✔✔NOPE The REB does not have the mandate to assess a study based on the likelihood that it will be published. However, the REB may require modifications to the protocol if it deems that the proposed method is likely to fail to answer the question under study and, therefore, the protocol does not strike a good balance between risks and the potential benefits.
TCPS 2 does not take precedence over provincial and territorial laws. A large team of researchers made up of biologists, social scientists, epidemiologists and statisticians from Canada and around the world want to conduct a study that aims to determine the social and biological predispositions to chronic diseases of Aboriginal peoples in Canada. As part of this research, in-depth interviews will be conducted with people residing in First Nations, Inuit and Métis territories. In addition, saliva and blood samples will be collected for genomic analysis. Choose the correct answer: In the context of research with Aboriginal communities, the three fundamental principles of TCPS 2 do not apply. In the context of research with indigenous communities, community agreement is more important than individual participant consent. In the context of research with Aboriginal communities, having a research agreement signed is more important than obtaining the individual consent of the participants. A - ✔✔None of these answers. The ethical requirements for research with Indigenous communities described in Chapter 9 of TCPS 2 should not invalidate or diminish the importance of the ethical requirements found in other chapters of TCPS 2. Which of the following statements is true? (choose all that apply) REB review is not always required for research requiring the secondary use of anonymized information. (your answer) For research requiring the secondary use of non-identifying information, researchers are not required to seek REB review. Researchers who have not obtained consent from participants for secondary use of identifiable human biological materials should always attempt to contact participants again to obtain their consent. For a research project requiring the secondary use of non-identifying information, researchers must obtain the consent of the participants, but they are not required to request a REB review. (your answer) For a research project requiring the secondary use of non-identifying information, researchers must seek REB review, but they are not required to seek consent from participants. - ✔✔REB review is not always required for research requiring the secondary use of anonymized information. For research involving the secondary use of non-identifiable information, researchers shall seek REB review, but are not required to seek participant consent A new virus is spreading among human populations, and the mechanisms that explain how it spreads are not well defined. One theory is that the virus is spread from person to person in workplaces due to mosquitoes. If this theory is true, installing mosquito nets in workplaces would sufficiently protect
employees from this new virus. However, the scientific data do not allow for the moment to determine if this hypothesis is correct. While an epidemic is raging in a foreign country, a Canadian researcher affiliated with an institution eligible for agency funding proposes a research protocol whose objective is to verify this hypothesis. The study methodology basically consists of recruiting employees working for different employers and randomly assigning them to group A (use of mosquito nets) or group B (control group not using mosquito nets). Subsequently, the relative effectiveness of the nets will be evaluated accordi - ✔✔Yes Any research conducted by a researcher at a Canadian institution is the responsibility of that institution. A new virus is spreading among human populations, and the mechanisms that explain how it spreads are not well defined. One theory is that the virus is spread from person to person in workplaces due to mosquitoes. If this theory is true, installing mosquito nets in workplaces would sufficiently protect employees from this new virus. However, the scientific data do not allow for the moment to determine if this hypothesis is correct. While an epidemic is raging in a foreign country, a Canadian researcher affiliated with an institution eligible for agency funding proposes a research protocol whose objective is to verify this hypothesis. The study methodology basically consists of recruiting employees working for different employers and randomly assigning them to group A (use of mosquito nets) or group B (control group not using mosquito nets). Subsequently, the relative effectiveness of the nets will be evaluated accordi - ✔✔yes Otherwise, the validity of the study results could be undermined by an actual conflict of interest, or challenged due to an apparent conflict of interest. A researcher from a Canadian institution eligible for agency funding wants to determine the frequency of cannabis use among high school students in Canada. The researcher plans to create a website that will contain a secure link to a survey that students who wish to participate in the research can complete. For scientific reasons, only students who have ever used cannabis will be invited to participate in the survey and answer it anonymously (answer all questions with YES or NO). If the REB determines that the target population and prospective participants have the capacity to decide for themselves to participate in the study, should the REB require the researcher to obtain permission from a parent or authorized third party before underage participants take part in the research project in this context? YES (your answer) NOPE - ✔✔Nope In this case, it has been determined that minors have the capacity to make a decision on their own. Requiring permission from a parent or authorized third party could negatively impact the privacy of students who wish to participate in the study. Participant consent may be obtained other than in writing. True (your answer)
A debriefing session to inform participants should follow all research projects that use deception. (your answer) It may be ethically acceptable, in certain circumstances and under specific conditions, to conduct research that poses more than minimal risk and involves the deception of participants. In general, researchers should favor research projects conducted with participants capable of making decisions and protecting their interests. When a third party has authorized a participant's participation and the participant regains decision- making capacity, the researcher must obtain the participant's consent. - ✔✔ Which of the following statements is/are true? (choose all that apply) Some people are inherently vulnerable and should therefore be excluded from most research projects. In general, conduct research with participants living in low- and middle-income countries should be avoided, as the power relationship between researchers and participants may compromise the voluntary consent of the latter. Some communities are inherently vulnerable and should therefore be excluded from most research projects. In general, research with pregnant participants should be avoided because of the risks such research may present. It is sometimes necessary to exclude people of advanced age from research when the burden resulting from their participation in research is greater than the potential benefits that they could derive from it. (your answer) - ✔✔It is sometimes necessary to exclude people of advanced age from research when the burden resulting from their participation in research is greater than the potential benefits that they could derive from it. A large team of researchers made up of biologists, social scientists, epidemiologists and statisticians from Canada and around the world want to conduct a study that aims to determine the social and biological predispositions to chronic diseases of Aboriginal peoples in Canada. As part of this research, in-depth interviews will be conducted with people residing in First Nations, Inuit and Métis territories. In addition, saliva and blood samples will be collected for genomic analysis. Choose the correct answer: REB review and community consultation should be undertaken at the same time. (your answer) Researchers should seek REB review before consulting the community. Researchers should consult with the community before requesting REB review. - ✔✔Researchers should consult with the community before requesting REB review. To be able to assess the ethical acceptability of research involving Indigenous communities, REBs must have evidence of community involvement. Therefore, researchers should initiate a community engagement process before seeking REB review.
A new virus is spreading among human populations, and the mechanisms that explain how it spreads are not well defined. One theory is that the virus is spread from person to person in workplaces due to mosquitoes. If this theory is true, installing mosquito nets in workplaces would sufficiently protect employees from this new virus. However, the scientific data do not allow for the moment to determine if this hypothesis is correct. While an epidemic is raging in a foreign country, a Canadian researcher affiliated with an institution eligible for agency funding proposes a research protocol whose objective is to verify this hypothesis. The study methodology basically consists of recruiting employees working for different employers and randomly assigning them to group A (use of mosquito nets) or group B (control group not using mosquito nets). Subsequently, the relative effectiveness of the nets will be evaluated accordi - ✔✔NOPE The power relationship between employers and employees as well as potential conflicts of interest could constitute an undesirable influence when recruiting participants, which could compromise the voluntary nature of consent. A researcher from a Canadian institution eligible for agency funding wants to determine the frequency of cannabis use among high school students in Canada. The researcher plans to create a website that will contain a secure link to a survey that students who wish to participate in the research can complete. For scientific reasons, only students who have ever used cannabis will be invited to participate in the survey and answer it anonymously (answer all questions with YES or NO). The researcher wants to ask teachers to inform their students of the existence of the study and explain to them how they can access the link that leads to the survey in case they want to answer it, whether at home or not. anywhere outside the classroom. The school board has approved the proposal, the teachers are not members of the research team, and the context is not likely to exert coercive pressure on students to participate in the study - ✔✔Yes According to the information provided, the voluntariness of the consent is protected and therefore the proposal is acceptable. A large team of researchers made up of biologists, social scientists, epidemiologists and statisticians from Canada and around the world want to conduct a study that aims to determine the social and biological predispositions to chronic diseases of Aboriginal peoples in Canada. As part of this research, in-depth interviews will be conducted with people residing in First Nations, Inuit and Métis territories. In addition, saliva and blood samples will be collected for genomic analysis. The researchers plan to conduct in-depth interviews in which they will ask members of Indigenous communities to provide information about their diet and lifestyle. Choose the correct answer: Some research projects involving Indigenous communities may meet minimal risk research criteria and be assessed under delegated review. In the context of research with Indigenous communities, it is the REB's responsibility to determine whether a giv - ✔✔All of these answers.