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Renal Physiology & renal disease overview
Typology: Study notes
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<
Excretory
:
mesenchyset
part
: weteric bed
connecting
tubule +
collecting
duct
weter +
calyces
pelvis
Kidney
S
7
T
glomerulus
7
Vascular
function
:
,
ā Mitochondria
,
&
water
(passive process
SALT-2-secondary
active
ā
of
acute tubular
<*
& demand
a
supply
ā
sepsis/drugs
Ā·
permeable
to 10
Ā· Thick
Ascending
(OH
Nak'Cr
and
site
for
ATI
.
Types
of
nephron
:
05 %
/p
of
Lo a
junction of
OM
and in
Juxtamedullary
: 15 %
(tip
of
LOH inside
--
modified
Tall
Columnar
cells
of
DCT
buloglomerular feedback
Macla
Messa
sense
tubula
na
ā¦
Renin
of afferent
acterials
ā
ā
serum creatinine
(findings)
Ā·
if
load
decrease
afferent
dilation
I
efferent
constriction GFR
.
stimulus
hypo
perfusion a
PaEz/Pais
, receptor
A In SKD
no
of
nephson
to maintain GFR
glomeruli undergoes hyberfiltration
.
intraglomeras
GIN
Capillary pare
size I
if
Etinuria
ā
#PROTEINURIA
interstitia inflammatio a
--p-
fibrosis
150
mg/day
protein
-> Tamm
Horsfall
mucoprotein
produced
by
thick
ascending
LOM
30-300mg/day
L
diabetic
glomerular
disease
v Tubular
p
.
to tubula interstitium dis
Fo
eflow p
.
multiple
myeloma
,
Rhabdomyolysis
Ā·
glomerular
physi
fee
exe an
ATURiA
.
<
3 RBC/ per field)
Blood
during
intually voiding
Metha cause
Blood
during voidingI
full
time
Blood
during
end
of voiding
/
Bladder Base
do
coloured
wine
Renal
pelvis/lower
UT -
Pink/red
pain
:
,
pyelonephritis
,
renal calculus
tenderness
ApoSyndromes)
family history
Ā·
of
RBC cast
Bleeding from
Kidney (often-glomerulonephritis)
Ā·
acanthocytes
ds
of
glomerular
origin
Ā·
uniform
UT
Ā·
clumps of
RBL
.
Minary
Tract
<Upper
/
Kidney
,
uta
Prostate)
ā
Capillary
Endothelium :
endothelium covered
by
glycocalyx
(negative
invey
(A)
no
proteinuria
B
microhematuriaSEN
ā”
:
mason's trichome
stain
at birth
: <
,
4
,
42
after
birth
<*
, Cochlea Br
,
Ocula BM
Skin BM , Tubulal
BM
.
Alport
syndrome
/80 (linked
Skinimmunofluoroscence
a
